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Murcko scaffold

Ring system with 2 rings and 12 atoms

40 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
40
With full pages
3
Scaffold SMILES

c1cc(CN2CCCCC2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(CN2CCCCC2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

1-(Thiophen-3-ylmethyl)piperidine-3-carbohydrazide chemical structure, C11H17N3OS, CAS 415937-73-4
1-(Thiophen-3-ylmethyl)piperidine-3-carbohydrazide
CAS 415937-73-4C11H17N3OS
1-(Thiophen-3-ylmethyl)piperidin-3-ol chemical structure, C10H15NOS, CAS 331976-44-4
1-(Thiophen-3-ylmethyl)piperidin-3-ol
CAS 331976-44-4C10H15NOS
1-(Thiophen-3-ylmethyl)piperidine-3-carboxylic acid chemical structure, C11H15NO2S, CAS 746581-91-9
1-(Thiophen-3-ylmethyl)piperidine-3-carboxylic acid
CAS 746581-91-9C11H15NO2S
1-(Thiophen-3-ylmethyl)piperidine-4-carboxylic acid chemical structure, C11H15NO2S, CAS 901923-87-3
1-(Thiophen-3-ylmethyl)piperidine-4-carboxylic acid
CAS 901923-87-3C11H15NO2S
Ethyl 5-amino-4-cyano-3-(1-piperidinylmethyl)-2-thiophenecarboxylate chemical structure, C14H19N3O2S, CAS 132651-59-3
Ethyl 5-amino-4-cyano-3-(1-piperidinylmethyl)-2-thiophenecarboxylate
CAS 132651-59-3C14H19N3O2S
N-Methyl-1-[3-(piperidin-1-ylmethyl)-2-thienyl]methanamine chemical structure, C12H20N2S, CAS 937651-18-8
N-Methyl-1-[3-(piperidin-1-ylmethyl)-2-thienyl]methanamine
CAS 937651-18-8C12H20N2S
4-[(Piperidin-1-yl)methyl]thiophene-2-carbaldehyde chemical structure, C11H15NOS, CAS 893745-85-2
4-[(Piperidin-1-yl)methyl]thiophene-2-carbaldehyde
CAS 893745-85-2C11H15NOS
[1-(Thiophen-3-ylmethyl)piperidin-2-yl]methanol chemical structure, C11H17NOS, CAS 162469-57-0
[1-(Thiophen-3-ylmethyl)piperidin-2-yl]methanol
CAS 162469-57-0C11H17NOS
{1-[(Thiophen-3-yl)methyl]piperidin-3-yl}methanol chemical structure, C11H17NOS, CAS 864410-74-2
{1-[(Thiophen-3-yl)methyl]piperidin-3-yl}methanol
CAS 864410-74-2C11H17NOS
1-(Thiophen-3-ylmethyl)piperidin-4-amine chemical structure, C10H16N2S, CAS 933737-29-2
1-(Thiophen-3-ylmethyl)piperidin-4-amine
CAS 933737-29-2C10H16N2S
1-(Thiophen-3-ylmethyl)piperidin-4-ol chemical structure, C10H15NOS, CAS 864388-84-1
1-(Thiophen-3-ylmethyl)piperidin-4-ol
CAS 864388-84-1C10H15NOS
{1-[(Thiophen-3-yl)methyl]piperidin-3-yl}methanamine chemical structure, C11H18N2S, CAS 1154619-75-6
{1-[(Thiophen-3-yl)methyl]piperidin-3-yl}methanamine
CAS 1154619-75-6C11H18N2S
1-{1-[(Thiophen-3-yl)methyl]piperidin-4-yl}methanamine chemical structure, C11H18N2S, CAS 1154619-82-5
1-{1-[(Thiophen-3-yl)methyl]piperidin-4-yl}methanamine
CAS 1154619-82-5C11H18N2S
N-((1-(Thiophen-3-ylmethyl)piperidin-4-yl)methyl)methanesulfonamide chemical structure, C12H20N2O2S2, CAS 1235269-56-3
N-((1-(Thiophen-3-ylmethyl)piperidin-4-yl)methyl)methanesulfonamide
CAS 1235269-56-3C12H20N2O2S2
2-Ethoxy-N-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)acetamide chemical structure, C15H24N2O2S, CAS 1235061-95-6
2-Ethoxy-N-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)acetamide
CAS 1235061-95-6C15H24N2O2S
N1-methyl-N2-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)oxalamide chemical structure, C14H21N3O2S, CAS 1234807-94-3
N1-methyl-N2-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)oxalamide
CAS 1234807-94-3C14H21N3O2S
1-[(Thiophen-3-yl)methyl]piperidin-3-amine chemical structure, C10H16N2S, CAS 1248157-51-8
1-[(Thiophen-3-yl)methyl]piperidin-3-amine
CAS 1248157-51-8C10H16N2S
I+/--Ethyl-I(2)-3-thienyl-1-piperidineethanamine chemical structure, C13H22N2S, CAS 1248103-33-4
I+/--Ethyl-I(2)-3-thienyl-1-piperidineethanamine
CAS 1248103-33-4C13H22N2S
{1-[(Thiophen-3-yl)methyl]piperidin-4-yl}methanol chemical structure, C11H17NOS, CAS 1249314-74-6
{1-[(Thiophen-3-yl)methyl]piperidin-4-yl}methanol
CAS 1249314-74-6C11H17NOS
1-(1-(Thiophen-3-ylmethyl)piperidin-3-yl)ethan-1-amine chemical structure, C12H20N2S, CAS 1341287-89-5
1-(1-(Thiophen-3-ylmethyl)piperidin-3-yl)ethan-1-amine
CAS 1341287-89-5C12H20N2S
N-({1-[(Thiophen-3-yl)methyl]piperidin-4-yl}methyl)ethane-1-sulfonamide chemical structure, C13H22N2O2S2, CAS 1235382-48-5
N-({1-[(Thiophen-3-yl)methyl]piperidin-4-yl}methyl)ethane-1-sulfonamide
CAS 1235382-48-5C13H22N2O2S2
N-((1-(Thiophen-3-ylmethyl)piperidin-4-yl)methyl)propane-1-sulfonamide chemical structure, C14H24N2O2S2, CAS 1235234-91-9
N-((1-(Thiophen-3-ylmethyl)piperidin-4-yl)methyl)propane-1-sulfonamide
CAS 1235234-91-9C14H24N2O2S2
2-Methyl-N-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)propane-1-sulfonamide chemical structure, C15H26N2O2S2, CAS 1235031-25-0
2-Methyl-N-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)propane-1-sulfonamide
CAS 1235031-25-0C15H26N2O2S2
2-Methoxy-N-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)acetamide chemical structure, C14H22N2O2S, CAS 1234907-56-2
2-Methoxy-N-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)acetamide
CAS 1234907-56-2C14H22N2O2S