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Murcko scaffold

Ring system with 2 rings and 17 atoms

25 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
25
With full pages
7
Scaffold SMILES

O=C(CN1C(=O)CNC1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN1C(=O)CNC1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Ethyl 4-{[(2,5-dioxo-1-imidazolidinyl)acetyl]amino}benzoate chemical structure, C14H15N3O5, CAS 824942-14-5
Ethyl 4-{[(2,5-dioxo-1-imidazolidinyl)acetyl]amino}benzoate
CAS 824942-14-5C14H15N3O5
2-(2,5-Dioxoimidazolidin-1-yl)-N-(p-tolyl)acetamide chemical structure, C12H13N3O3, CAS 638991-49-8
2-(2,5-Dioxoimidazolidin-1-yl)-N-(p-tolyl)acetamide
CAS 638991-49-8C12H13N3O3
N-(4-Chlorophenyl)-2-(2,5-dioxoimidazolidin-1-yl)acetamide chemical structure, C11H10ClN3O3, CAS 638991-67-0
N-(4-Chlorophenyl)-2-(2,5-dioxoimidazolidin-1-yl)acetamide
CAS 638991-67-0C11H10ClN3O3
2-(3-Methyl-2,5-dioxoimidazolidin-1-yl)-N-phenylacetamide chemical structure, C12H13N3O3, CAS 730253-01-7
2-(3-Methyl-2,5-dioxoimidazolidin-1-yl)-N-phenylacetamide
CAS 730253-01-7C12H13N3O3
2-(2,5-Dioxo-4,4-dipropylimidazolidin-1-yl)-N-(4-iodophenyl)acetamide chemical structure, C17H22IN3O3, CAS 879626-94-5
2-(2,5-Dioxo-4,4-dipropylimidazolidin-1-yl)-N-(4-iodophenyl)acetamide
CAS 879626-94-5C17H22IN3O3
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(3-methylphenyl)acetamide chemical structure, C16H21N3O3, CAS 941905-07-3
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(3-methylphenyl)acetamide
CAS 941905-07-3C16H21N3O3
2-[4-Methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]-N-(2,3,4-trifluorophenyl)acetamide chemical structure, C16H18F3N3O3, CAS 957002-83-4
2-[4-Methyl-4-(2-methylpropyl)-2,5-dioxoimidazolidin-1-yl]-N-(2,3,4-trifluorophenyl)acetamide
CAS 957002-83-4C16H18F3N3O3
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(2,4-dimethylphenyl)acetamide chemical structure, C17H23N3O3, CAS 852703-99-2
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(2,4-dimethylphenyl)acetamide
CAS 852703-99-2C17H23N3O3
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C18H25N3O3, CAS 853338-09-7
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(2,4,6-trimethylphenyl)acetamide
CAS 853338-09-7C18H25N3O3
2-(4-Butyl-4-methyl-2,5-dioxoimidazolidin-1-yl)-N-(4-chloro-2-methylphenyl)acetamide chemical structure, C17H22ClN3O3, CAS 956684-80-3
2-(4-Butyl-4-methyl-2,5-dioxoimidazolidin-1-yl)-N-(4-chloro-2-methylphenyl)acetamide
CAS 956684-80-3C17H22ClN3O3
2-(2,5-Dioxoimidazolidin-1-yl)-N-(4-sulfamoylphenyl)acetamide chemical structure, C11H12N4O5S, CAS 858207-24-6
2-(2,5-Dioxoimidazolidin-1-yl)-N-(4-sulfamoylphenyl)acetamide
CAS 858207-24-6C11H12N4O5S
2-(3-Methyl-2,5-dioxoimidazolidin-1-yl)-N-(4-methylphenyl)acetamide chemical structure, C13H15N3O3, CAS 915890-44-7
2-(3-Methyl-2,5-dioxoimidazolidin-1-yl)-N-(4-methylphenyl)acetamide
CAS 915890-44-7C13H15N3O3
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(2,4-difluorophenyl)acetamide chemical structure, C15H17F2N3O3, CAS 941913-00-4
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(2,4-difluorophenyl)acetamide
CAS 941913-00-4C15H17F2N3O3
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(3,5-dimethylphenyl)acetamide chemical structure, C17H23N3O3, CAS 942034-05-1
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(3,5-dimethylphenyl)acetamide
CAS 942034-05-1C17H23N3O3
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(2,5-dimethylphenyl)acetamide chemical structure, C17H23N3O3, CAS 941912-98-7
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(2,5-dimethylphenyl)acetamide
CAS 941912-98-7C17H23N3O3
Methyl 4-[2-(4,4-diethyl-2,5-dioxoimidazolidin-1-yl)acetamido]benzoate chemical structure, C17H21N3O5, CAS 875284-59-6
Methyl 4-[2-(4,4-diethyl-2,5-dioxoimidazolidin-1-yl)acetamido]benzoate
CAS 875284-59-6C17H21N3O5
N-[4-(Difluoromethoxy)phenyl]-2-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)acetamide chemical structure, C14H15F2N3O4, CAS 1001756-85-9
N-[4-(Difluoromethoxy)phenyl]-2-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)acetamide
CAS 1001756-85-9C14H15F2N3O4
2-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-N-(3-ethylphenyl)acetamide chemical structure, C15H19N3O3, CAS 923230-57-3
2-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-N-(3-ethylphenyl)acetamide
CAS 923230-57-3C15H19N3O3
N-(4-Bromo-2-methylphenyl)-4-(1-methylethyl)-2,5-dioxo-1-imidazolidineacetamide chemical structure, C15H18BrN3O3, CAS 1025447-41-9
N-(4-Bromo-2-methylphenyl)-4-(1-methylethyl)-2,5-dioxo-1-imidazolidineacetamide
CAS 1025447-41-9C15H18BrN3O3
N-(2-Amino-4-methoxyphenyl)-2-(2,5-dioxoimidazolidin-1-yl)acetamide chemical structure, C12H14N4O4, CAS 954253-95-3
N-(2-Amino-4-methoxyphenyl)-2-(2,5-dioxoimidazolidin-1-yl)acetamide
CAS 954253-95-3C12H14N4O4
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(o-tolyl)acetamide chemical structure, C16H21N3O3, CAS 942034-03-9
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(o-tolyl)acetamide
CAS 942034-03-9C16H21N3O3
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(4-fluorophenyl)acetamide chemical structure, C15H18FN3O3, CAS 941905-10-8
2-(4,4-Diethyl-2,5-dioxoimidazolidin-1-yl)-N-(4-fluorophenyl)acetamide
CAS 941905-10-8C15H18FN3O3
N-(3-(2-(4,4-Dimethyl-2,5-dioxo-imidazolin-1-yl)-4,4-dimethyl-3-oxo-pentanoylamino)-4-methoxy-phenyl)-octadecanamide chemical structure, C37H60N4O6, CAS 150919-56-5
N-(3-(2-(4,4-Dimethyl-2,5-dioxo-imidazolin-1-yl)-4,4-dimethyl-3-oxo-pentanoylamino)-4-methoxy-phenyl)-octadecanamide
CAS 150919-56-5C37H60N4O6
N-(2-Amino-4-methylphenyl)-3-methyl-2,5-dioxo-1-imidazolidineacetamide chemical structure, C13H16N4O3, CAS 1096864-15-1
N-(2-Amino-4-methylphenyl)-3-methyl-2,5-dioxo-1-imidazolidineacetamide
CAS 1096864-15-1C13H16N4O3