CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
11
With full pages
10
Scaffold SMILES

O=c1ccnc(N2CCN(c3ccccc3)CC2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccnc(N2CCN(c3ccccc3)CC2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

6-Amino-2-(4-phenyl-1-piperazinyl)-4-pyrimidinol chemical structure, C14H17N5O, CAS 33080-88-5
6-Amino-2-(4-phenyl-1-piperazinyl)-4-pyrimidinol
CAS 33080-88-5C14H17N5O
2-[4-(2-Fluorophenyl)piperazin-1-yl]-5,6-dimethylpyrimidin-4(3H)-one chemical structure, C16H19FN4O, CAS 876667-32-2
2-[4-(2-Fluorophenyl)piperazin-1-yl]-5,6-dimethylpyrimidin-4(3H)-one
CAS 876667-32-2C16H19FN4O
2-[4-(3-Methoxyphenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one chemical structure, C16H20N4O2, CAS 880076-34-6
2-[4-(3-Methoxyphenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one
CAS 880076-34-6C16H20N4O2
5,6-Dimethyl-2-(4-phenylpiperazin-1-yl)pyrimidin-4(3H)-one chemical structure, C16H20N4O, CAS 878973-99-0
5,6-Dimethyl-2-(4-phenylpiperazin-1-yl)pyrimidin-4(3H)-one
CAS 878973-99-0C16H20N4O
2-[4-(3-Chlorophenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one chemical structure, C15H17ClN4O, CAS 907986-71-4
2-[4-(3-Chlorophenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one
CAS 907986-71-4C15H17ClN4O
2-[4-(2-Methoxyphenyl)piperazin-1-yl]-6-methyl-5-propylpyrimidin-4(3H)-one chemical structure, C19H26N4O2, CAS 886153-23-7
2-[4-(2-Methoxyphenyl)piperazin-1-yl]-6-methyl-5-propylpyrimidin-4(3H)-one
CAS 886153-23-7C19H26N4O2
2-[4-(4-Chlorophenyl)piperazin-1-yl]-5-ethyl-6-methylpyrimidin-4(3H)-one chemical structure, C17H21ClN4O, CAS 886152-86-9
2-[4-(4-Chlorophenyl)piperazin-1-yl]-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS 886152-86-9C17H21ClN4O
2-[4-(3-Methoxyphenyl)piperazin-1-yl]-6-methyl-5-propylpyrimidin-4(3H)-one chemical structure, C19H26N4O2, CAS 886153-87-3
2-[4-(3-Methoxyphenyl)piperazin-1-yl]-6-methyl-5-propylpyrimidin-4(3H)-one
CAS 886153-87-3C19H26N4O2
5-Ethyl-2-[4-(3-methoxyphenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one chemical structure, C18H24N4O2, CAS 886153-79-3
5-Ethyl-2-[4-(3-methoxyphenyl)piperazin-1-yl]-6-methylpyrimidin-4(3H)-one
CAS 886153-79-3C18H24N4O2
2-(4-(4-Chlorophenyl)-1-piperazinyl)-5,6-dimethyl-4(3H)-pyrimidinone chemical structure, C16H19ClN4O, CAS 886152-79-0
2-(4-(4-Chlorophenyl)-1-piperazinyl)-5,6-dimethyl-4(3H)-pyrimidinone
CAS 886152-79-0C16H19ClN4O
5-Ethyl-6-methyl-2-(4-phenylpiperazin-1-yl)pyrimidin-4(3H)-one chemical structure, C17H22N4O, CAS 886151-79-7
5-Ethyl-6-methyl-2-(4-phenylpiperazin-1-yl)pyrimidin-4(3H)-one
CAS 886151-79-7C17H22N4O