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Murcko scaffold

Ring system with 3 rings and 20 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
16
With full pages
13
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1cc2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1cc2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

3,5-Dimethyl-N-[(E)-(4-nitrophenyl)methylideneamino]-1H-indole-2-carboxamide chemical structure, C18H16N4O3, CAS 289721-64-8
3,5-Dimethyl-N-[(E)-(4-nitrophenyl)methylideneamino]-1H-indole-2-carboxamide
CAS 289721-64-8C18H16N4O3
5-Ethoxy-N-[(E)-(2-methoxyphenyl)methylideneamino]-1H-indole-2-carboxamide chemical structure, C19H19N3O3, CAS 896594-61-9
5-Ethoxy-N-[(E)-(2-methoxyphenyl)methylideneamino]-1H-indole-2-carboxamide
CAS 896594-61-9C19H19N3O3
5-Methoxy-N-[(E)-(2-methoxyphenyl)methylideneamino]-1H-indole-2-carboxamide chemical structure, C18H17N3O3, CAS 896810-72-3
5-Methoxy-N-[(E)-(2-methoxyphenyl)methylideneamino]-1H-indole-2-carboxamide
CAS 896810-72-3C18H17N3O3
4,5-Dimethoxy-N-[(E)-(2-methoxyphenyl)methylideneamino]-1H-indole-2-carboxamide chemical structure, C19H19N3O4, CAS 896818-61-4
4,5-Dimethoxy-N-[(E)-(2-methoxyphenyl)methylideneamino]-1H-indole-2-carboxamide
CAS 896818-61-4C19H19N3O4
6-Methoxy-N-[(E)-(3,4,5-trimethoxyphenyl)methylideneamino]-1H-indole-2-carboxamide chemical structure, C20H21N3O5, CAS 896836-33-2
6-Methoxy-N-[(E)-(3,4,5-trimethoxyphenyl)methylideneamino]-1H-indole-2-carboxamide
CAS 896836-33-2C20H21N3O5
5,6-Dimethoxy-N-[(E)-(4-methoxyphenyl)methylideneamino]-1H-indole-2-carboxamide chemical structure, C19H19N3O4, CAS 846596-61-0
5,6-Dimethoxy-N-[(E)-(4-methoxyphenyl)methylideneamino]-1H-indole-2-carboxamide
CAS 846596-61-0C19H19N3O4
N-[(E)-(2-Chlorophenyl)methylideneamino]-5,6-dimethoxy-1H-indole-2-carboxamide chemical structure, C18H16ClN3O3, CAS 848063-29-6
N-[(E)-(2-Chlorophenyl)methylideneamino]-5,6-dimethoxy-1H-indole-2-carboxamide
CAS 848063-29-6C18H16ClN3O3
N-[(E)-(3-Hydroxy-4-methoxyphenyl)methylideneamino]-5-methoxy-1H-indole-2-carboxamide chemical structure, C18H17N3O4, CAS 896067-38-2
N-[(E)-(3-Hydroxy-4-methoxyphenyl)methylideneamino]-5-methoxy-1H-indole-2-carboxamide
CAS 896067-38-2C18H17N3O4
5-Chloro-N'-(1-(2,5-dimethoxyphenyl)ethylidene)-1-methyl-1H-indole-2-carbohydrazide chemical structure, C20H20ClN3O3, CAS 764713-23-7
5-Chloro-N'-(1-(2,5-dimethoxyphenyl)ethylidene)-1-methyl-1H-indole-2-carbohydrazide
CAS 764713-23-7C20H20ClN3O3
N'-[(E)-(4-Fluorophenyl)methylidene]-5,6-dimethoxy-1H-indole-2-carbohydrazide chemical structure, C18H16FN3O3, CAS 846597-78-2
N'-[(E)-(4-Fluorophenyl)methylidene]-5,6-dimethoxy-1H-indole-2-carbohydrazide
CAS 846597-78-2C18H16FN3O3
2-Benzyliden-1-(3-aminoindol)-2-carbohydrazide chemical structure, C16H14N4O, CAS 135086-99-6
2-Benzyliden-1-(3-aminoindol)-2-carbohydrazide
CAS 135086-99-6C16H14N4O
N'-[(E)-(4-Hydroxy-3-methoxyphenyl)methylidene]-1H-indole-2-carbohydrazide chemical structure, C17H15N3O3, CAS 15315-60-3
N'-[(E)-(4-Hydroxy-3-methoxyphenyl)methylidene]-1H-indole-2-carbohydrazide
CAS 15315-60-3C17H15N3O3
N'-[(E)-(2-Hydroxyphenyl)methylidene]-4,7-dimethoxy-1H-indole-2-carbohydrazide chemical structure, C18H17N3O4, CAS 896821-39-9
N'-[(E)-(2-Hydroxyphenyl)methylidene]-4,7-dimethoxy-1H-indole-2-carbohydrazide
CAS 896821-39-9C18H17N3O4
N'-[(E)-(2,4-Dihydroxyphenyl)methylidene]-5-methoxy-1H-indole-2-carbohydrazide chemical structure, C17H15N3O4, CAS 896854-29-8
N'-[(E)-(2,4-Dihydroxyphenyl)methylidene]-5-methoxy-1H-indole-2-carbohydrazide
CAS 896854-29-8C17H15N3O4
N'-[(E)-(2-Hydroxyphenyl)methylidene]-4,6-dimethoxy-1H-indole-2-carbohydrazide chemical structure, C18H17N3O4, CAS 896594-62-0
N'-[(E)-(2-Hydroxyphenyl)methylidene]-4,6-dimethoxy-1H-indole-2-carbohydrazide
CAS 896594-62-0C18H17N3O4
5-Methoxy-N'-[(4-methylphenyl)methylidene]-1H-indole-2-carbohydrazide chemical structure, C18H17N3O2, CAS 56635-24-6
5-Methoxy-N'-[(4-methylphenyl)methylidene]-1H-indole-2-carbohydrazide
CAS 56635-24-6C18H17N3O2