Murcko scaffold
N-[2-(1H-Benzoimidazol-2-yl)-ethyl]-benzamide scaffold
50 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 20
- Chemicals
- 50
- With full pages
- 24
Scaffold SMILES
O=C(NCCc1nc2ccccc2[nH]1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=C(NCCc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/YRGGTYXDASSWSH-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 50 chemicals
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-2-methoxybenzamide chemical structure, C17H17N3O2, CAS 672331-17-8](/s/COQCZJXXLKSKJA-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-2-methoxybenzamide
CAS 672331-17-8C17H17N3O2
![N-[2-(1H-Benzoimidazol-2-yl)-ethyl]-benzamide chemical structure, C16H15N3O, CAS 107313-47-3](/s/YRGGTYXDASSWSH-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzoimidazol-2-yl)-ethyl]-benzamide
CAS 107313-47-3C16H15N3O
![N-(2-(1H-Benzo[d]imidazol-2-yl)ethyl)-3-methoxybenzamide chemical structure, C17H17N3O2, CAS 302950-26-1](/s/HAFBPQILQUFGIY-UHFFFAOYSA-N.svg)
N-(2-(1H-Benzo[d]imidazol-2-yl)ethyl)-3-methoxybenzamide
CAS 302950-26-1C17H17N3O2
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-methylbenzamide chemical structure, C17H17N3O, CAS 302558-80-1](/s/SDBHIUOHGKZTHG-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-methylbenzamide
CAS 302558-80-1C17H17N3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-3,4-dimethoxybenzamide chemical structure, C18H19N3O3, CAS 303991-75-5](/s/UNKSHFBNOQYCEQ-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-3,4-dimethoxybenzamide
CAS 303991-75-5C18H19N3O3
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-2-chlorobenzamide chemical structure, C16H14ClN3O, CAS 300821-01-6](/s/CHRWNGZHKRIDQQ-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-2-chlorobenzamide
CAS 300821-01-6C16H14ClN3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-nitrobenzamide chemical structure, C16H14N4O3, CAS 300821-02-7](/s/YRKQEVHZBYTOMJ-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-nitrobenzamide
CAS 300821-02-7C16H14N4O3
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-chloro-3-nitrobenzamide chemical structure, C16H13ClN4O3, CAS 301682-03-1](/s/GYWDNVCGQOXZBI-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-chloro-3-nitrobenzamide
CAS 301682-03-1C16H13ClN4O3
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-methyl-3-nitrobenzamide chemical structure, C17H16N4O3, CAS 302949-47-9](/s/JPRUSVVGPCANJQ-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-methyl-3-nitrobenzamide
CAS 302949-47-9C17H16N4O3
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-3-bromobenzamide chemical structure, C16H14BrN3O, CAS 302950-22-7](/s/HKYPRNSPCNMSQK-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-3-bromobenzamide
CAS 302950-22-7C16H14BrN3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-2-bromobenzamide chemical structure, C16H14BrN3O, CAS 329224-03-5](/s/VLDXWUUAMYVLKX-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-2-bromobenzamide
CAS 329224-03-5C16H14BrN3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-2,4-dichlorobenzamide chemical structure, C16H13Cl2N3O, CAS 303991-74-4](/s/WVQVBXSDNMFRRB-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-2,4-dichlorobenzamide
CAS 303991-74-4C16H13Cl2N3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-3,4-dichlorobenzamide chemical structure, C16H13Cl2N3O, CAS 303991-76-6](/s/HFOGJQIGORZVGU-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-3,4-dichlorobenzamide
CAS 303991-76-6C16H13Cl2N3O
![N-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]-3-methylbenzamide chemical structure, C17H17N3O, CAS 303991-77-7](/s/WEKDMJNWYYYARY-UHFFFAOYSA-N.svg)
N-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]-3-methylbenzamide
CAS 303991-77-7C17H17N3O
![N-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]-2-methylbenzamide chemical structure, C17H17N3O, CAS 303991-78-8](/s/KBRBCAIFUKKRCU-UHFFFAOYSA-N.svg)
N-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]-2-methylbenzamide
CAS 303991-78-8C17H17N3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-3-chlorobenzamide chemical structure, C16H14ClN3O, CAS 303991-79-9](/s/VILVWNPZUYLTPC-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-3-chlorobenzamide
CAS 303991-79-9C16H14ClN3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-fluorobenzamide chemical structure, C16H14FN3O, CAS 301228-23-9](/s/XKCPJXSGCGSDHR-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-fluorobenzamide
CAS 301228-23-9C16H14FN3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-bromobenzamide chemical structure, C16H14BrN3O, CAS 301228-29-5](/s/WHYGAXUMRLXJGG-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-bromobenzamide
CAS 301228-29-5C16H14BrN3O
![N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-chlorobenzamide chemical structure, C16H14ClN3O, CAS 301228-32-0](/s/ABPNEUMCHOAVQP-UHFFFAOYSA-N.svg)
N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-chlorobenzamide
CAS 301228-32-0C16H14ClN3O
![N-[2-(1-Methylbenzimidazol-2-yl)ethyl]benzamide chemical structure, C17H17N3O, CAS 686736-09-4](/s/PNKKVXYFCLJZKO-UHFFFAOYSA-N.svg)
N-[2-(1-Methylbenzimidazol-2-yl)ethyl]benzamide
CAS 686736-09-4C17H17N3O
![3-Methyl-N-[2-(1-methylbenzimidazol-2-yl)ethyl]benzamide chemical structure, C18H19N3O, CAS 850922-06-4](/s/ZCBFAFDAHKTURJ-UHFFFAOYSA-N.svg)
3-Methyl-N-[2-(1-methylbenzimidazol-2-yl)ethyl]benzamide
CAS 850922-06-4C18H19N3O
![4-Chloro-N-[2-(1-methylbenzimidazol-2-yl)ethyl]benzamide chemical structure, C17H16ClN3O, CAS 850922-07-5](/s/WHMJUSOQWYBVEB-UHFFFAOYSA-N.svg)
4-Chloro-N-[2-(1-methylbenzimidazol-2-yl)ethyl]benzamide
CAS 850922-07-5C17H16ClN3O
![N-[2-(1-Ethylbenzimidazol-2-yl)ethyl]-3-methylbenzamide chemical structure, C19H21N3O, CAS 831247-00-8](/s/OJDKQSLRBPAXLK-UHFFFAOYSA-N.svg)
N-[2-(1-Ethylbenzimidazol-2-yl)ethyl]-3-methylbenzamide
CAS 831247-00-8C19H21N3O
![N-[2-(1-Ethylbenzimidazol-2-yl)ethyl]-4-fluorobenzamide chemical structure, C18H18FN3O, CAS 850922-15-5](/s/FMRJTUNPMWAPIF-UHFFFAOYSA-N.svg)
N-[2-(1-Ethylbenzimidazol-2-yl)ethyl]-4-fluorobenzamide
CAS 850922-15-5C18H18FN3O
- 2-Methoxy-N-[2-(1-propylbenzimidazol-2-yl)ethyl]benzamide850922-24-6C20H23N3O2
- N-{2-[1-(2-Methylprop-2-enyl)benzimidazol-2-yl]ethyl}benzamide686736-23-2C20H21N3O
- N-[2-(1H-Benzimidazol-2-yl)ethyl]-2,6-difluorobenzamide727661-70-3C16H13F2N3O
- N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-(2-methylpropoxy)benzamide673445-08-4C20H23N3O2
- 3-Acetamido-N-[2-(1H-benzimidazol-2-yl)ethyl]benzamide672944-38-6C18H18N4O2
- N-[2-(1H-Benzimidazol-2-yl)ethyl]-3,6-dichloro-2-methoxybenzamide301680-38-6C17H15Cl2N3O2
- N-[2-(1H-Benzimidazol-2-yl)ethyl]-3,4,5-trimethoxybenzamide303122-38-5C19H21N3O4
- N-[2-(1H-Benzimidazol-2-yl)ethyl]-2-ethoxybenzamide302559-77-9C18H19N3O2
- N-[2-(1H-Benzimidazol-2-yl)ethyl]-3,4-dimethylbenzamide442570-94-7C18H19N3O
- N-[2-(1H-Benzimidazol-2-yl)ethyl]-4-methoxybenzamide305377-02-0C17H17N3O2
- N-[2-(1-Methyl-5-nitrobenzimidazol-2-yl)ethyl]benzamide830352-08-4C17H16N4O3
- N-[2-(1-Butyl-1H-benzimidazol-2-yl)ethyl]-4-fluorobenzamide831241-06-6C20H22FN3O
- 3-Methyl-N-[2-(1-prop-2-ynylbenzimidazol-2-yl)ethyl]benzamide872347-22-3C20H19N3O
- N-[2-(1-Ethyl-1H-benzimidazol-2-yl)ethyl]-3,4-dimethoxybenzamide850922-17-7C20H23N3O3
- 3-Methyl-N-(2-(1-(2-methylallyl)-1H-benzo[d]imidazol-2-yl)ethyl)benzamide850923-30-7C21H23N3O
- N-[2-(1-Ethylbenzimidazol-2-yl)ethyl]benzamide686736-13-0C18H19N3O
- 4-Chloro-N-[2-(1-propylbenzimidazol-2-yl)ethyl]benzamide850922-22-4C19H20ClN3O
- N-[2-(1-Butyl-1H-benzimidazol-2-yl)ethyl]-2-methoxybenzamide850922-38-2C21H25N3O2
- 2-Methoxy-N-{2-[1-(2-methylpropyl)-1H-benzimidazol-2-yl]ethyl}benzamide850922-93-9C21H25N3O2
- 3,4-Dimethoxy-N-{2-[1-(2-methylpropyl)-1H-1,3-benzodiazol-2-yl]ethyl}benzamide850922-95-1C22H27N3O3
- N-[2-(1-Ethylbenzimidazol-2-yl)ethyl]-2-methoxybenzamide850922-16-6C19H21N3O2
- 2-Methoxy-N-{2-[1-(prop-2-en-1-yl)-1H-1,3-benzodiazol-2-yl]ethyl}benzamide850923-22-7C20H21N3O2
- 2-Methoxy-N-[2-(1-methyl-5-nitrobenzimidazol-2-yl)ethyl]benzamide895835-30-0C18H18N4O4
- 4-Methoxy-N-[2-(1-methyl-5-nitrobenzimidazol-2-yl)ethyl]benzamide895824-91-6C18H18N4O4
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CSc1nc2ccccc2[nH]1)Nc1ccccc1](/scaffold/WVWIDWYWASPVGN-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc2ccccc2[nH]1)Nc1ccccc149 chemicals![Scaffold c1ccc(OCCSc2nc3ccccc3[nH]2)cc1](/scaffold/UEYUFQWEHMSHIX-UHFFFAOYSA-N/structure.svg)
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O=C(COc1ccccc1)Nc1cc2c(s1)CCCC220 chemicals
O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc1ccccc119 chemicals
O=C(CCN1C(=O)c2ccccc2C1=O)Nc1ccccc118 chemicals
O=C(CS(=O)(=O)c1ccccc1)Nc1nc2ccccc2s117 chemicals
O=C(CSc1nc2ccccc2s1)Nc1ccccc114 chemicals![Scaffold O=C(NN=Cc1ccccc1)c1cc2ccccc2[nH]1](/scaffold/SYUQFFCOGGAGKC-UHFFFAOYSA-N/structure.svg)
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O=C(CN1C(=O)c2ccccc2S1(=O)=O)NCc1ccccc111 chemicals
O=C(CCc1ccccc1)Nc1nc2ccccc2s111 chemicals