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Murcko scaffold

Ring system with 2 rings and 14 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
11
With full pages
5
Scaffold SMILES

O=C1NC(=O)C(=Cc2cccnc2)S1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=O)C(=Cc2cccnc2)S1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

(5E)-5-[(6-Chloropyridin-3-yl)methylidene]-1,3-thiazolidine-2,4-dione chemical structure, C9H5ClN2O2S, CAS 329695-22-9
(5E)-5-[(6-Chloropyridin-3-yl)methylidene]-1,3-thiazolidine-2,4-dione
CAS 329695-22-9C9H5ClN2O2S
3-(2-Aminoethyl)-5-(pyridin-3-ylmethylidene)-1,3-thiazolidine-2,4-dione chemical structure, C11H11N3O2S, CAS 377769-59-0
3-(2-Aminoethyl)-5-(pyridin-3-ylmethylidene)-1,3-thiazolidine-2,4-dione
CAS 377769-59-0C11H11N3O2S
3-(2-Aminoethyl)-5-(3-pyridylmethylene)-1,3-thiazolidine-2,4-dione chemical structure, C11H11N3O2S
3-(2-Aminoethyl)-5-(3-pyridylmethylene)-1,3-thiazolidine-2,4-dione
C11H11N3O2S
4-[(5Z)-2,4-Dioxo-5-(pyridin-3-ylmethylidene)-1,3-thiazolidin-3-yl]butanoic acid chemical structure, C13H12N2O4S, CAS 847379-49-1
4-[(5Z)-2,4-Dioxo-5-(pyridin-3-ylmethylidene)-1,3-thiazolidin-3-yl]butanoic acid
CAS 847379-49-1C13H12N2O4S
3-[(5Z)-2,4-Dioxo-5-(pyridin-3-ylmethylidene)-1,3-thiazolidin-3-yl]propanoic acid chemical structure, C12H10N2O4S, CAS 847176-66-3
3-[(5Z)-2,4-Dioxo-5-(pyridin-3-ylmethylidene)-1,3-thiazolidin-3-yl]propanoic acid
CAS 847176-66-3C12H10N2O4S
2-[(5Z)-2,4-Dioxo-5-(pyridin-1-ium-3-ylmethylidene)-1,3-thiazolidin-3-yl]acetate chemical structure, C11H8N2O4S, CAS 178881-11-3
2-[(5Z)-2,4-Dioxo-5-(pyridin-1-ium-3-ylmethylidene)-1,3-thiazolidin-3-yl]acetate
CAS 178881-11-3C11H8N2O4S
2-Chloro-N-{2-[2,4-dioxo-5-(pyridin-3-ylmethylidene)-1,3-thiazolidin-3-yl]ethyl}acetamide chemical structure, C13H12ClN3O3S, CAS 554439-42-8
2-Chloro-N-{2-[2,4-dioxo-5-(pyridin-3-ylmethylidene)-1,3-thiazolidin-3-yl]ethyl}acetamide
CAS 554439-42-8C13H12ClN3O3S
3-(2-Aminoethyl)-5-(pyridin-3-ylmethylidene)-1,3-thiazolidine-2,4-dione chemical structure, C11H11N3O2S
3-(2-Aminoethyl)-5-(pyridin-3-ylmethylidene)-1,3-thiazolidine-2,4-dione
C11H11N3O2S
3-Methyl-5-[(E)-3-pyridinylmethylidene]-1,3-thiazolane-2,4-dione chemical structure, C10H8N2O2S, CAS 1164525-51-2
3-Methyl-5-[(E)-3-pyridinylmethylidene]-1,3-thiazolane-2,4-dione
CAS 1164525-51-2C10H8N2O2S
(5E)-3-(2-Aminoethyl)-5-(pyridin-3-ylmethylidene)-1,3-thiazolidine-2,4-dione hydrochloride chemical structure, C11H12ClN3O2S, CAS 478792-15-3
(5E)-3-(2-Aminoethyl)-5-(pyridin-3-ylmethylidene)-1,3-thiazolidine-2,4-dione hydrochloride
CAS 478792-15-3C11H12ClN3O2S
2-Chloro-N-(2-{2,4-dioxo-5-[(pyridin-3-yl)methylidene]-1,3-thiazolidin-3-yl}ethyl)acetamide hydrochloride chemical structure, C13H13Cl2N3O3S, CAS 2197131-61-4
2-Chloro-N-(2-{2,4-dioxo-5-[(pyridin-3-yl)methylidene]-1,3-thiazolidin-3-yl}ethyl)acetamide hydrochloride
CAS 2197131-61-4C13H13Cl2N3O3S