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Murcko scaffold

Ring system with 2 rings and 13 atoms

5 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
5
With full pages
1
Scaffold SMILES

O=C1C=COC1=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=COC1=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

RefChem:357310 chemical structure, C15H14O4, CAS 53252-49-6
RefChem:357310
CAS 53252-49-6C15H14O4
(E)-Ethyl 5-(4-methoxybenzylidene)-2-methyl-4-oxo-4,5-dihydrofuran-3-carboxylate chemical structure, C16H16O5, CAS 60404-04-8
(E)-Ethyl 5-(4-methoxybenzylidene)-2-methyl-4-oxo-4,5-dihydrofuran-3-carboxylate
CAS 60404-04-8C16H16O5
Ethyl (5E)-5-[(3-chlorophenyl)methylidene]-2-methyl-4-oxofuran-3-carboxylate chemical structure, C15H13ClO4, CAS 63194-88-7
Ethyl (5E)-5-[(3-chlorophenyl)methylidene]-2-methyl-4-oxofuran-3-carboxylate
CAS 63194-88-7C15H13ClO4
3(2H)-Furanone, 4-acetyl-2-[(4-chlorophenyl)methylene]-5-methyl- chemical structure, C14H11ClO3, CAS 62723-17-5
3(2H)-Furanone, 4-acetyl-2-[(4-chlorophenyl)methylene]-5-methyl-
CAS 62723-17-5C14H11ClO3
Inotilone chemical structure, C12H10O4, CAS 906366-79-8
Inotilone
CAS 906366-79-8C12H10O4