CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
20
With full pages
3
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccc(N2CCCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1ccc(N2CCCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

2-(2-Ethylphenoxy)-N-[4-(piperidin-1-yl)phenyl]acetamide chemical structure, C21H26N2O2, CAS 449749-62-6
2-(2-Ethylphenoxy)-N-[4-(piperidin-1-yl)phenyl]acetamide
CAS 449749-62-6C21H26N2O2
2-(2-Methylphenoxy)-N-(4-piperidin-1-ylphenyl)acetamide chemical structure, C20H24N2O2, CAS 425653-75-4
2-(2-Methylphenoxy)-N-(4-piperidin-1-ylphenyl)acetamide
CAS 425653-75-4C20H24N2O2
2-(3-Methylphenoxy)-N-(4-piperidin-1-ylphenyl)acetamide chemical structure, C20H24N2O2, CAS 625398-74-5
2-(3-Methylphenoxy)-N-(4-piperidin-1-ylphenyl)acetamide
CAS 625398-74-5C20H24N2O2
2-(4-Chloro-2-methylphenoxy)-N-(4-piperidylphenyl)acetamide chemical structure, C20H23ClN2O2, CAS 303118-91-4
2-(4-Chloro-2-methylphenoxy)-N-(4-piperidylphenyl)acetamide
CAS 303118-91-4C20H23ClN2O2
2-(4-Bromophenoxy)-N-(3-chloro-4-piperidin-1-ylphenyl)acetamide chemical structure, C19H20BrClN2O2, CAS 347336-22-5
2-(4-Bromophenoxy)-N-(3-chloro-4-piperidin-1-ylphenyl)acetamide
CAS 347336-22-5C19H20BrClN2O2
2-(4-Chlorophenoxy)-N-(3-chloro-4-piperidin-1-ylphenyl)acetamide chemical structure, C19H20Cl2N2O2, CAS 347336-30-5
2-(4-Chlorophenoxy)-N-(3-chloro-4-piperidin-1-ylphenyl)acetamide
CAS 347336-30-5C19H20Cl2N2O2
2-(3-Bromophenoxy)-N-(4-piperidin-1-ylphenyl)acetamide chemical structure, C19H21BrN2O2, CAS 302805-61-4
2-(3-Bromophenoxy)-N-(4-piperidin-1-ylphenyl)acetamide
CAS 302805-61-4C19H21BrN2O2
2-[3-Methyl-4-(propan-2-yl)phenoxy]-N-[4-(piperidin-1-yl)phenyl]acetamide chemical structure, C23H30N2O2, CAS 430471-26-4
2-[3-Methyl-4-(propan-2-yl)phenoxy]-N-[4-(piperidin-1-yl)phenyl]acetamide
CAS 430471-26-4C23H30N2O2
2-(2-Ethoxyphenoxy)-N-[4-(1-piperidinyl)phenyl]acetamide chemical structure, C21H26N2O3, CAS 634162-14-4
2-(2-Ethoxyphenoxy)-N-[4-(1-piperidinyl)phenyl]acetamide
CAS 634162-14-4C21H26N2O3
N-(4-Piperidin-1-ylphenyl)-2-(2,4,5-trichlorophenoxy)acetamide chemical structure, C19H19Cl3N2O2, CAS 432005-42-0
N-(4-Piperidin-1-ylphenyl)-2-(2,4,5-trichlorophenoxy)acetamide
CAS 432005-42-0C19H19Cl3N2O2
2-(4-Chloro-3,5-dimethylphenoxy)-N-(4-piperidin-1-ylphenyl)acetamide chemical structure, C21H25ClN2O2, CAS 431930-25-5
2-(4-Chloro-3,5-dimethylphenoxy)-N-(4-piperidin-1-ylphenyl)acetamide
CAS 431930-25-5C21H25ClN2O2
N-(3-Chloro-4-piperidin-1-ylphenyl)-2-(2-methylphenoxy)acetamide chemical structure, C20H23ClN2O2, CAS 431934-35-9
N-(3-Chloro-4-piperidin-1-ylphenyl)-2-(2-methylphenoxy)acetamide
CAS 431934-35-9C20H23ClN2O2
2-(4-Methoxyphenoxy)-N-(4-piperidin-1-ylphenyl)acetamide chemical structure, C20H24N2O3, CAS 403643-73-2
2-(4-Methoxyphenoxy)-N-(4-piperidin-1-ylphenyl)acetamide
CAS 403643-73-2C20H24N2O3
N-[4-(4-Methylpiperidin-1-yl)phenyl]-2-(4-propan-2-ylphenoxy)acetamide chemical structure, C23H30N2O2, CAS 700857-21-2
N-[4-(4-Methylpiperidin-1-yl)phenyl]-2-(4-propan-2-ylphenoxy)acetamide
CAS 700857-21-2C23H30N2O2
N-[4-(4-Methylpiperidin-1-yl)phenyl]-2-(4-nitrophenoxy)acetamide chemical structure, C20H23N3O4, CAS 700861-40-1
N-[4-(4-Methylpiperidin-1-yl)phenyl]-2-(4-nitrophenoxy)acetamide
CAS 700861-40-1C20H23N3O4
N-[3-Chloro-4-(piperidin-1-yl)phenyl]-2-(2,4-dichlorophenoxy)acetamide chemical structure, C19H19Cl3N2O2, CAS 625409-27-0
N-[3-Chloro-4-(piperidin-1-yl)phenyl]-2-(2,4-dichlorophenoxy)acetamide
CAS 625409-27-0C19H19Cl3N2O2
N-[4-(4-Methylpiperidin-1-yl)phenyl]-2-phenoxyacetamide chemical structure, C20H24N2O2, CAS 801243-89-0
N-[4-(4-Methylpiperidin-1-yl)phenyl]-2-phenoxyacetamide
CAS 801243-89-0C20H24N2O2
N-[3-Fluoro-4-(1-piperidinyl)phenyl]-2-phenoxyacetamide chemical structure, C19H21FN2O2, CAS 899122-16-8
N-[3-Fluoro-4-(1-piperidinyl)phenyl]-2-phenoxyacetamide
CAS 899122-16-8C19H21FN2O2
2-(2,4-Dichlorophenoxy)-N-[4-(4-methoxypiperidin-1-yl)phenyl]acetamide chemical structure, C20H22Cl2N2O3, CAS 1798037-48-5
2-(2,4-Dichlorophenoxy)-N-[4-(4-methoxypiperidin-1-yl)phenyl]acetamide
CAS 1798037-48-5C20H22Cl2N2O3
2-(4-Chlorophenoxy)-N-[4-(3-methoxypiperidin-1-yl)phenyl]acetamide chemical structure, C20H23ClN2O3, CAS 1797872-90-2
2-(4-Chlorophenoxy)-N-[4-(3-methoxypiperidin-1-yl)phenyl]acetamide
CAS 1797872-90-2C20H23ClN2O3