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Murcko scaffold

5-(Benzylthio)-1,3,4-thiadiazole-2-thiol scaffold

15 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
15
With full pages
5
Scaffold SMILES

S=c1[nH]nc(SCc2ccccc2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Benzylthio)-1,3,4-thiadiazole-2-thiol page
Murcko scaffold S=c1[nH]nc(SCc2ccccc2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

5-((2-Chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl hydrosulfide chemical structure, C9H7ClN2S3, CAS 345991-75-5
5-((2-Chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl hydrosulfide
CAS 345991-75-5C9H7ClN2S3
5-(Benzylthio)-1,3,4-thiadiazole-2-thiol chemical structure, C9H8N2S3, CAS 4858-36-0
5-(Benzylthio)-1,3,4-thiadiazole-2-thiol
CAS 4858-36-0C9H8N2S3
5-{[(4-Chlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazole-2-thiol chemical structure, C9H7ClN2S3, CAS 4858-38-2
5-{[(4-Chlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazole-2-thiol
CAS 4858-38-2C9H7ClN2S3
5-{[(4-Fluorophenyl)methyl]sulfanyl}-1,3,4-thiadiazole-2-thiol chemical structure, C9H7FN2S3, CAS 757220-77-2
5-{[(4-Fluorophenyl)methyl]sulfanyl}-1,3,4-thiadiazole-2-thiol
CAS 757220-77-2C9H7FN2S3
5-({[4-(Propan-2-yl)phenyl]methyl}sulfanyl)-1,3,4-thiadiazole-2-thiol chemical structure, C12H14N2S3, CAS 790681-66-2
5-({[4-(Propan-2-yl)phenyl]methyl}sulfanyl)-1,3,4-thiadiazole-2-thiol
CAS 790681-66-2C12H14N2S3
5-[(2,6-Dichlorobenzyl)thio]-1,3,4-thiadiazole-2-thiol chemical structure, C9H6Cl2N2S3, CAS 210285-94-2
5-[(2,6-Dichlorobenzyl)thio]-1,3,4-thiadiazole-2-thiol
CAS 210285-94-2C9H6Cl2N2S3
5-{[(4-Methoxyphenyl)methyl]sulfanyl}-1,3,4-thiadiazole-2-thiol chemical structure, C10H10N2OS3, CAS 136384-20-8
5-{[(4-Methoxyphenyl)methyl]sulfanyl}-1,3,4-thiadiazole-2-thiol
CAS 136384-20-8C10H10N2OS3
5-(3-Chlorobenzylthio)-2-mercapto-1,3,4-thiadiazole chemical structure, C9H7ClN2S3, CAS 444791-16-6
5-(3-Chlorobenzylthio)-2-mercapto-1,3,4-thiadiazole
CAS 444791-16-6C9H7ClN2S3
5-(2,4-Dichlorobenzylthio)-2-mercapto-1,3,4-thiadiazole chemical structure, C9H6Cl2N2S3, CAS 136384-19-5
5-(2,4-Dichlorobenzylthio)-2-mercapto-1,3,4-thiadiazole
CAS 136384-19-5C9H6Cl2N2S3
5-[[[3-(Trifluoromethyl)phenyl]methyl]thio]-1,3,4-thiadiazole-2(3H)-thione chemical structure, C10H7F3N2S3, CAS 175277-94-8
5-[[[3-(Trifluoromethyl)phenyl]methyl]thio]-1,3,4-thiadiazole-2(3H)-thione
CAS 175277-94-8C10H7F3N2S3
4-[(5-Sulfanyl-1,3,4-thiadiazol-2-ylthio)methyl]benzoic acid chemical structure, C10H8N2O2S3, CAS 107859-96-1
4-[(5-Sulfanyl-1,3,4-thiadiazol-2-ylthio)methyl]benzoic acid
CAS 107859-96-1C10H8N2O2S3
5-[[(3-Nitrophenyl)methyl]thio]-1,3,4-thiadiazole-2(3H)-thione chemical structure, C9H7N3O2S3, CAS 136384-21-9
5-[[(3-Nitrophenyl)methyl]thio]-1,3,4-thiadiazole-2(3H)-thione
CAS 136384-21-9C9H7N3O2S3
5-((4-Methylbenzyl)thio)-1,3,4-thiadiazol-2-yl hydrosulfide chemical structure, C10H10N2S3, CAS 210285-93-1
5-((4-Methylbenzyl)thio)-1,3,4-thiadiazol-2-yl hydrosulfide
CAS 210285-93-1C10H10N2S3
5-((4-Vinylbenzyl)thio)-1,3,4-thiadiazole-2(3H)-thione chemical structure, C11H10N2S3, CAS 174728-86-0
5-((4-Vinylbenzyl)thio)-1,3,4-thiadiazole-2(3H)-thione
CAS 174728-86-0C11H10N2S3
5-{[(2-Ethenylphenyl)methyl]sulfanyl}-1,3,4-thiadiazole-2(3H)-thione chemical structure, C11H10N2S3, CAS 180053-43-4
5-{[(2-Ethenylphenyl)methyl]sulfanyl}-1,3,4-thiadiazole-2(3H)-thione
CAS 180053-43-4C11H10N2S3