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Murcko scaffold

Ring system with 2 rings and 14 atoms

116 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
116
With full pages
12
Scaffold SMILES

O=C1NC(=O)C(=Cc2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=O)C(=Cc2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 116 chemicals

5-((4-Ethoxyphenyl)methylene)imidazolidine-2,4-dione chemical structure, C12H12N2O3
5-((4-Ethoxyphenyl)methylene)imidazolidine-2,4-dione
C12H12N2O3
5-Vanillylidenehydantoin chemical structure, C11H10N2O4, CAS 52036-16-5
5-Vanillylidenehydantoin
CAS 52036-16-5C11H10N2O4
5-[(4-Methylphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C11H10N2O2, CAS 28744-88-9
5-[(4-Methylphenyl)methylidene]imidazolidine-2,4-dione
CAS 28744-88-9C11H10N2O2
5-[[4-(Dimethylamino)phenyl]methylidene]imidazolidine-2,4-dione chemical structure, C12H13N3O2
5-[[4-(Dimethylamino)phenyl]methylidene]imidazolidine-2,4-dione
C12H13N3O2
5-(3-Nitrobenzylidene)imidazolidine-2,4-dione chemical structure, C10H7N3O4, CAS 137943-39-6
5-(3-Nitrobenzylidene)imidazolidine-2,4-dione
CAS 137943-39-6C10H7N3O4
(5E)-5-[(2-Bromo-4-ethoxy-5-methoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C13H13BrN2O4, CAS 431976-79-3
(5E)-5-[(2-Bromo-4-ethoxy-5-methoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 431976-79-3C13H13BrN2O4
5-(p-Methoxybenzylidene)hydantoin chemical structure, C11H10N2O3, CAS 5349-42-8
5-(p-Methoxybenzylidene)hydantoin
CAS 5349-42-8C11H10N2O3
(5E)-5-[(5-Chloro-2-methoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C11H9ClN2O3, CAS 431909-15-8
(5E)-5-[(5-Chloro-2-methoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 431909-15-8C11H9ClN2O3
(5E)-5-[(5-Bromo-2-hydroxy-3-methoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C11H9BrN2O4, CAS 431996-61-1
(5E)-5-[(5-Bromo-2-hydroxy-3-methoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 431996-61-1C11H9BrN2O4
(5E)-5-[(2,4-Dimethoxy-3-methylphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C13H14N2O4, CAS 432015-47-9
(5E)-5-[(2,4-Dimethoxy-3-methylphenyl)methylidene]imidazolidine-2,4-dione
CAS 432015-47-9C13H14N2O4
5-[1-(2-Fluoro-phenyl)-meth-(Z)-ylidene]-imidazolidine-2,4-dione chemical structure, C10H7FN2O2, CAS 403500-19-6
5-[1-(2-Fluoro-phenyl)-meth-(Z)-ylidene]-imidazolidine-2,4-dione
CAS 403500-19-6C10H7FN2O2
5-(4-Methylbenzylidene)imidazolidine-2,4-dione chemical structure, C11H10N2O2, CAS 120697-21-4
5-(4-Methylbenzylidene)imidazolidine-2,4-dione
CAS 120697-21-4C11H10N2O2
(Z)-5-(4-Methylbenzylidene)imidazolidine-2,4-dione chemical structure, C11H10N2O2, CAS 109754-07-6
(Z)-5-(4-Methylbenzylidene)imidazolidine-2,4-dione
CAS 109754-07-6C11H10N2O2
(5Z)-5-(3-Methylbenzylidene)imidazolidine-2,4-dione chemical structure, C11H10N2O2, CAS 432001-00-8
(5Z)-5-(3-Methylbenzylidene)imidazolidine-2,4-dione
CAS 432001-00-8C11H10N2O2
(5E)-5-[(3,5-Dichloro-4-ethoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C12H10Cl2N2O3, CAS 432008-36-1
(5E)-5-[(3,5-Dichloro-4-ethoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 432008-36-1C12H10Cl2N2O3
(5E)-5-[(4-Fluorophenyl)methylidene]imidazolidine-2,4-dione chemical structure, C10H7FN2O2, CAS 300827-96-7
(5E)-5-[(4-Fluorophenyl)methylidene]imidazolidine-2,4-dione
CAS 300827-96-7C10H7FN2O2
5-(4-Dimethylamino-benzylidene)-imidazolidine-2,4-dione chemical structure, C12H13N3O2, CAS 10040-87-6
5-(4-Dimethylamino-benzylidene)-imidazolidine-2,4-dione
CAS 10040-87-6C12H13N3O2
(E)-5-(3,4,5-Trimethoxybenzylidene)imidazolidine-2,4-dione chemical structure, C13H14N2O5, CAS 23585-90-2
(E)-5-(3,4,5-Trimethoxybenzylidene)imidazolidine-2,4-dione
CAS 23585-90-2C13H14N2O5
(5E)-5-(2-Methoxy-5-nitrobenzylidene)imidazolidine-2,4-dione chemical structure, C11H9N3O5, CAS 432538-07-3
(5E)-5-(2-Methoxy-5-nitrobenzylidene)imidazolidine-2,4-dione
CAS 432538-07-3C11H9N3O5
(5E)-5-(2,3,4-Trimethoxybenzylidene)imidazolidine-2,4-dione chemical structure, C13H14N2O5, CAS 174272-57-2
(5E)-5-(2,3,4-Trimethoxybenzylidene)imidazolidine-2,4-dione
CAS 174272-57-2C13H14N2O5
(5E)-5-[(3-Methoxy-2-propan-2-yloxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C14H16N2O4, CAS 432010-02-1
(5E)-5-[(3-Methoxy-2-propan-2-yloxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 432010-02-1C14H16N2O4
5-(3,4-Dichlorobenzylidene)imidazolidine-2,4-dione chemical structure, C10H6Cl2N2O2, CAS 6318-39-4
5-(3,4-Dichlorobenzylidene)imidazolidine-2,4-dione
CAS 6318-39-4C10H6Cl2N2O2
5-(3-Ethoxy-4-methoxybenzylidene)-3-ethylimidazolidine-2,4-dione chemical structure, C15H18N2O4, CAS 666212-28-8
5-(3-Ethoxy-4-methoxybenzylidene)-3-ethylimidazolidine-2,4-dione
CAS 666212-28-8C15H18N2O4
(5E)-5-[(3-Chloro-4-ethoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C12H11ClN2O3, CAS 425613-57-6
(5E)-5-[(3-Chloro-4-ethoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 425613-57-6C12H11ClN2O3