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Murcko scaffold

Ring system with 2 rings and 14 atoms

116 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
116
With full pages
12
Scaffold SMILES

O=C1NC(=O)C(=Cc2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=O)C(=Cc2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 116 chemicals

1-Acetyl-5-[(3-methoxy-4-propoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C16H18N2O5, CAS 308292-50-4
1-Acetyl-5-[(3-methoxy-4-propoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 308292-50-4C16H18N2O5
2,4-Imidazolidinedione, 5-[(4-ethylphenyl)methylene]- chemical structure, C12H12N2O2
2,4-Imidazolidinedione, 5-[(4-ethylphenyl)methylene]-
C12H12N2O2
5-[(2-Chlorophenyl)methylidene]imidazolidine-2,4-dione chemical structure, C10H7ClN2O2, CAS 7449-58-3
5-[(2-Chlorophenyl)methylidene]imidazolidine-2,4-dione
CAS 7449-58-3C10H7ClN2O2
5-[(4-Chlorophenyl)methylidene]imidazolidine-2,4-dione chemical structure, C10H7ClN2O2
5-[(4-Chlorophenyl)methylidene]imidazolidine-2,4-dione
C10H7ClN2O2
2,4-Imidazolidinedione, 3-methyl-5-(phenylmethylene)- chemical structure, C11H10N2O2, CAS 31113-71-0
2,4-Imidazolidinedione, 3-methyl-5-(phenylmethylene)-
CAS 31113-71-0C11H10N2O2
5-[(4-Bromophenyl)methylidene]imidazolidine-2,4-dione chemical structure, C10H7BrN2O2, CAS 28744-89-0
5-[(4-Bromophenyl)methylidene]imidazolidine-2,4-dione
CAS 28744-89-0C10H7BrN2O2
5-[(4-Hydroxy-3-methoxy-5-nitrophenyl)methylidene]imidazolidine-2,4-dione chemical structure, C11H9N3O6, CAS 5818-20-2
5-[(4-Hydroxy-3-methoxy-5-nitrophenyl)methylidene]imidazolidine-2,4-dione
CAS 5818-20-2C11H9N3O6
5-[(2-Hydroxy-3-methoxy-5-nitrophenyl)methylidene]imidazolidine-2,4-dione chemical structure, C11H9N3O6, CAS 5842-02-4
5-[(2-Hydroxy-3-methoxy-5-nitrophenyl)methylidene]imidazolidine-2,4-dione
CAS 5842-02-4C11H9N3O6
(5E)-5-[(3-Bromo-5-ethoxy-4-prop-2-ynoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C15H13BrN2O4, CAS 431979-00-9
(5E)-5-[(3-Bromo-5-ethoxy-4-prop-2-ynoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 431979-00-9C15H13BrN2O4
(5Z)-5-[(5-Chloro-2-hydroxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C10H7ClN2O3, CAS 354154-31-7
(5Z)-5-[(5-Chloro-2-hydroxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 354154-31-7C10H7ClN2O3
(5Z)-5-(4-Methoxybenzylidene)imidazolidine-2,4-dione chemical structure, C11H10N2O3, CAS 108402-52-4
(5Z)-5-(4-Methoxybenzylidene)imidazolidine-2,4-dione
CAS 108402-52-4C11H10N2O3
(5Z)-5-[(3-Ethoxy-4-methoxyphenyl)methylidene]-3-ethylimidazolidine-2,4-dione chemical structure, C15H18N2O4
(5Z)-5-[(3-Ethoxy-4-methoxyphenyl)methylidene]-3-ethylimidazolidine-2,4-dione
C15H18N2O4
(5Z)-5-(Phenylmethylene)-2,4-imidazolidinedione chemical structure, C10H8N2O2, CAS 3775-01-7
(5Z)-5-(Phenylmethylene)-2,4-imidazolidinedione
CAS 3775-01-7C10H8N2O2
(5Z)-5-(3-Bromo-4,5-dimethoxybenzylidene)imidazolidine-2,4-dione chemical structure, C12H11BrN2O4, CAS 2599844-50-3
(5Z)-5-(3-Bromo-4,5-dimethoxybenzylidene)imidazolidine-2,4-dione
CAS 2599844-50-3C12H11BrN2O4
(5E)-5-[(4-Prop-2-enoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C13H12N2O3, CAS 432014-76-1
(5E)-5-[(4-Prop-2-enoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 432014-76-1C13H12N2O3
(5E)-5-[3-Bromo-4-(butan-2-yloxy)benzylidene]imidazolidine-2,4-dione chemical structure, C14H15BrN2O3, CAS 432019-34-6
(5E)-5-[3-Bromo-4-(butan-2-yloxy)benzylidene]imidazolidine-2,4-dione
CAS 432019-34-6C14H15BrN2O3
(5E)-5-[4-(Butan-2-yloxy)-3-methoxybenzylidene]imidazolidine-2,4-dione chemical structure, C15H18N2O4, CAS 431906-30-8
(5E)-5-[4-(Butan-2-yloxy)-3-methoxybenzylidene]imidazolidine-2,4-dione
CAS 431906-30-8C15H18N2O4
(5E)-5-[(4-Butan-2-yloxy-3-chlorophenyl)methylidene]imidazolidine-2,4-dione chemical structure, C14H15ClN2O3, CAS 431909-06-7
(5E)-5-[(4-Butan-2-yloxy-3-chlorophenyl)methylidene]imidazolidine-2,4-dione
CAS 431909-06-7C14H15ClN2O3
(5E)-5-[(3-Chloro-5-methoxy-4-prop-2-ynoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C14H11ClN2O4, CAS 431937-74-5
(5E)-5-[(3-Chloro-5-methoxy-4-prop-2-ynoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 431937-74-5C14H11ClN2O4
(5E)-5-[(3-Methoxy-4-prop-2-ynoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C14H12N2O4, CAS 431941-38-7
(5E)-5-[(3-Methoxy-4-prop-2-ynoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 431941-38-7C14H12N2O4
(5E)-5-[(3-Iodo-5-methoxy-4-prop-2-ynoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C14H11IN2O4, CAS 431980-13-1
(5E)-5-[(3-Iodo-5-methoxy-4-prop-2-ynoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 431980-13-1C14H11IN2O4
(5E)-5-[3-Bromo-4-(butan-2-yloxy)-5-methoxybenzylidene]imidazolidine-2,4-dione chemical structure, C15H17BrN2O4, CAS 432497-05-7
(5E)-5-[3-Bromo-4-(butan-2-yloxy)-5-methoxybenzylidene]imidazolidine-2,4-dione
CAS 432497-05-7C15H17BrN2O4
(5E)-5-[(3-Bromo-5-ethoxy-4-prop-2-enoxyphenyl)methylidene]imidazolidine-2,4-dione chemical structure, C15H15BrN2O4, CAS 432538-16-4
(5E)-5-[(3-Bromo-5-ethoxy-4-prop-2-enoxyphenyl)methylidene]imidazolidine-2,4-dione
CAS 432538-16-4C15H15BrN2O4
5-(3'-Hydroxybenzylidene)hydantoin chemical structure, C10H8N2O3, CAS 91426-39-0
5-(3'-Hydroxybenzylidene)hydantoin
CAS 91426-39-0C10H8N2O3