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Murcko scaffold

5-Phenyluracil scaffold

158 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
158
With full pages
3
Scaffold SMILES

O=c1[nH]cc(-c2ccccc2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Phenyluracil page
Murcko scaffold O=c1[nH]cc(-c2ccccc2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 158 chemicals

5-Phenyluracil chemical structure, C10H8N2O2, CAS 15761-83-8
5-Phenyluracil
CAS 15761-83-8C10H8N2O2
Uracil, 3-(2-mercaptoethyl)-5-phenyl- chemical structure, C12H12N2O2S, CAS 29558-47-2
Uracil, 3-(2-mercaptoethyl)-5-phenyl-
CAS 29558-47-2C12H12N2O2S
5-(3-Bromophenyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C10H7BrN2O2, CAS 171003-67-1
5-(3-Bromophenyl)pyrimidine-2,4(1H,3H)-dione
CAS 171003-67-1C10H7BrN2O2
5-(3-Bromo-5-methylphenyl)-1H-pyrimidine-2,4-dione chemical structure, C11H9BrN2O2, CAS 176250-15-0
5-(3-Bromo-5-methylphenyl)-1H-pyrimidine-2,4-dione
CAS 176250-15-0C11H9BrN2O2
5-(3-Bromo-5-fluorophenyl)-1H-pyrimidine-2,4-dione chemical structure, C10H6BrFN2O2, CAS 176250-14-9
5-(3-Bromo-5-fluorophenyl)-1H-pyrimidine-2,4-dione
CAS 176250-14-9C10H6BrFN2O2
5-(3-Bromo-5-chlorophenyl)-1H-pyrimidine-2,4-dione chemical structure, C10H6BrClN2O2, CAS 176250-13-8
5-(3-Bromo-5-chlorophenyl)-1H-pyrimidine-2,4-dione
CAS 176250-13-8C10H6BrClN2O2
5-(3-Aminophenyl)-1H-pyrimidine-2,4-dione chemical structure, C10H9N3O2, CAS 188482-44-2
5-(3-Aminophenyl)-1H-pyrimidine-2,4-dione
CAS 188482-44-2C10H9N3O2
5-(3,4-Dimethoxyphenyl)-1H-pyrimidine-2,4-dione chemical structure, C12H12N2O4, CAS 94937-45-8
5-(3,4-Dimethoxyphenyl)-1H-pyrimidine-2,4-dione
CAS 94937-45-8C12H12N2O4
5-(4-Methoxyphenyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C11H10N2O3, CAS 127236-04-8
5-(4-Methoxyphenyl)pyrimidine-2,4(1H,3H)-dione
CAS 127236-04-8C11H10N2O3
5-(3-Methylsulfanylphenyl)-1H-pyrimidine-2,4-dione chemical structure, C11H10N2O2S, CAS 178411-21-7
5-(3-Methylsulfanylphenyl)-1H-pyrimidine-2,4-dione
CAS 178411-21-7C11H10N2O2S
5-(3-Methoxyphenyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C11H10N2O3, CAS 127236-03-7
5-(3-Methoxyphenyl)-2,4(1H,3H)-pyrimidinedione
CAS 127236-03-7C11H10N2O3
RefChem:313998 chemical structure, C12H11ClN2O2, CAS 51759-18-3
RefChem:313998
CAS 51759-18-3C12H11ClN2O2
5-(3-Chlorophenyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C10H7ClN2O2, CAS 178411-15-9
5-(3-Chlorophenyl)-2,4(1H,3H)-pyrimidinedione
CAS 178411-15-9C10H7ClN2O2
5-[2-(Trifluoromethyl)phenyl]-1H-pyrimidine-2,4-dione chemical structure, C11H7F3N2O2, CAS 151289-99-5
5-[2-(Trifluoromethyl)phenyl]-1H-pyrimidine-2,4-dione
CAS 151289-99-5C11H7F3N2O2
6-Azido-1,3-dimethyl-5-phenylpyrimidine-2,4(1H,3H)-dione chemical structure, C12H11N5O2, CAS 89549-99-5
6-Azido-1,3-dimethyl-5-phenylpyrimidine-2,4(1H,3H)-dione
CAS 89549-99-5C12H11N5O2
5-(2,5-Dimethylphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione chemical structure, C14H16N2O2, CAS 110225-42-8
5-(2,5-Dimethylphenyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
CAS 110225-42-8C14H16N2O2
6-Chloro-3-methyl-5-phenyl-1H-pyrimidine-2,4-dione chemical structure, C11H9ClN2O2, CAS 133801-12-4
6-Chloro-3-methyl-5-phenyl-1H-pyrimidine-2,4-dione
CAS 133801-12-4C11H9ClN2O2
5-(4-Chlorophenyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C10H7ClN2O2, CAS 116659-59-7
5-(4-Chlorophenyl)-2,4(1H,3H)-pyrimidinedione
CAS 116659-59-7C10H7ClN2O2
5-(4-Fluorophenyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C10H7FN2O2, CAS 893737-16-1
5-(4-Fluorophenyl)-2,4(1H,3H)-pyrimidinedione
CAS 893737-16-1C10H7FN2O2
5-(3-Fluorophenyl)-2,4(1H,3H)-pyrimidinedione chemical structure, C10H7FN2O2, CAS 893737-19-4
5-(3-Fluorophenyl)-2,4(1H,3H)-pyrimidinedione
CAS 893737-19-4C10H7FN2O2
(2,4)-Dihydroxy-5-(4-trifluoromethylphenyl)pyrimidine chemical structure, C11H7F3N2O2, CAS 893737-22-9
(2,4)-Dihydroxy-5-(4-trifluoromethylphenyl)pyrimidine
CAS 893737-22-9C11H7F3N2O2
5-[3-(Trifluoromethyl)phenyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C11H7F3N2O2, CAS 893737-25-2
5-[3-(Trifluoromethyl)phenyl]-2,4(1H,3H)-pyrimidinedione
CAS 893737-25-2C11H7F3N2O2
5-[4-(Methylsulfanyl)phenyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C11H10N2O2S, CAS 893737-27-4
5-[4-(Methylsulfanyl)phenyl]-2,4(1H,3H)-pyrimidinedione
CAS 893737-27-4C11H10N2O2S
Methyl 4-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)benzoate chemical structure, C12H10N2O4, CAS 893737-30-9
Methyl 4-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)benzoate
CAS 893737-30-9C12H10N2O4