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Murcko scaffold

Ring system with 3 rings and 21 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
15
With full pages
4
Scaffold SMILES

O=C(NCCSc1c[nH]c2ccccc12)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCSc1c[nH]c2ccccc12)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

3-Bromo-N-[2-(1H-indol-3-ylsulfanyl)ethyl]benzamide chemical structure, C17H15BrN2OS, CAS 687575-06-0
3-Bromo-N-[2-(1H-indol-3-ylsulfanyl)ethyl]benzamide
CAS 687575-06-0C17H15BrN2OS
N-[2-(1H-Indol-3-ylsulfanyl)ethyl]-2-(trifluoromethyl)benzamide chemical structure, C18H15F3N2OS, CAS 687571-80-8
N-[2-(1H-Indol-3-ylsulfanyl)ethyl]-2-(trifluoromethyl)benzamide
CAS 687571-80-8C18H15F3N2OS
N-[2-(1H-Indol-3-ylsulfanyl)ethyl]-3,5-dimethoxybenzamide chemical structure, C19H20N2O3S, CAS 687569-44-4
N-[2-(1H-Indol-3-ylsulfanyl)ethyl]-3,5-dimethoxybenzamide
CAS 687569-44-4C19H20N2O3S
N-[2-(1H-Indol-3-ylsulfanyl)ethyl]-2-methylbenzamide chemical structure, C18H18N2OS, CAS 687571-21-7
N-[2-(1H-Indol-3-ylsulfanyl)ethyl]-2-methylbenzamide
CAS 687571-21-7C18H18N2OS
2-Ethoxy-N-[2-(1H-indol-3-ylsulfanyl)ethyl]benzamide chemical structure, C19H20N2O2S, CAS 687569-81-9
2-Ethoxy-N-[2-(1H-indol-3-ylsulfanyl)ethyl]benzamide
CAS 687569-81-9C19H20N2O2S
4-Fluoro-N-[2-(1H-indol-3-ylsulfanyl)ethyl]benzamide chemical structure, C17H15FN2OS, CAS 687570-38-3
4-Fluoro-N-[2-(1H-indol-3-ylsulfanyl)ethyl]benzamide
CAS 687570-38-3C17H15FN2OS
3,4-Diethoxy-N-[2-(1H-indol-3-ylsulfanyl)ethyl]benzamide chemical structure, C21H24N2O3S, CAS 687574-94-3
3,4-Diethoxy-N-[2-(1H-indol-3-ylsulfanyl)ethyl]benzamide
CAS 687574-94-3C21H24N2O3S
4-Chloro-N-[2-(1H-indol-3-ylsulfanyl)ethyl]-3-nitrobenzamide chemical structure, C17H14ClN3O3S, CAS 687571-36-4
4-Chloro-N-[2-(1H-indol-3-ylsulfanyl)ethyl]-3-nitrobenzamide
CAS 687571-36-4C17H14ClN3O3S
2,3-Dimethoxy-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)benzamide chemical structure, C20H22N2O3S, CAS 687575-16-2
2,3-Dimethoxy-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)benzamide
CAS 687575-16-2C20H22N2O3S
4-Ethoxy-N-{2-[(2-methyl-1H-indol-3-yl)sulfanyl]ethyl}benzamide chemical structure, C20H22N2O2S, CAS 687569-68-2
4-Ethoxy-N-{2-[(2-methyl-1H-indol-3-yl)sulfanyl]ethyl}benzamide
CAS 687569-68-2C20H22N2O2S
4-Methyl-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)-3-nitrobenzamide chemical structure, C19H19N3O3S, CAS 850916-36-8
4-Methyl-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)-3-nitrobenzamide
CAS 850916-36-8C19H19N3O3S
4-Chloro-N-{2-[(2-methyl-1H-indol-3-yl)sulfanyl]ethyl}-3-nitrobenzamide chemical structure, C18H16ClN3O3S, CAS 687574-82-9
4-Chloro-N-{2-[(2-methyl-1H-indol-3-yl)sulfanyl]ethyl}-3-nitrobenzamide
CAS 687574-82-9C18H16ClN3O3S
3-Methyl-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)benzamide chemical structure, C19H20N2OS, CAS 687571-46-6
3-Methyl-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)benzamide
CAS 687571-46-6C19H20N2OS
4-Butoxy-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)benzamide chemical structure, C22H26N2O2S, CAS 687574-98-7
4-Butoxy-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)benzamide
CAS 687574-98-7C22H26N2O2S
4-Fluoro-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)benzamide chemical structure, C18H17FN2OS, CAS 687570-13-4
4-Fluoro-N-(2-((2-methyl-1H-indol-3-yl)thio)ethyl)benzamide
CAS 687570-13-4C18H17FN2OS