Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 18 atoms

20 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 20
With full pages: 9

Scaffold SMILES

O=c1cc(Nc2ccccc2)nc2ccccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1cc(Nc2ccccc2)nc2ccccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

7-Methyl-4-oxo-2-(phenylamino)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H13N3O2, CAS 302937-00-4

7-Methyl-4-oxo-2-(phenylamino)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 302937-00-4C₁₆H₁₃N₃O₂

2-[(4-Chlorophenyl)amino]-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H12ClN3O2, CAS 324049-94-7

2-[(4-Chlorophenyl)amino]-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 324049-94-7C₁₆H₁₂ClN₃O₂

2-(3-Chloroanilino)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H12ClN3O2, CAS 324037-15-2

2-(3-Chloroanilino)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 324037-15-2C₁₆H₁₂ClN₃O₂

2-[(4-Chlorophenyl)amino]-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H12ClN3O2, CAS 304864-86-6

2-[(4-Chlorophenyl)amino]-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 304864-86-6C₁₆H₁₂ClN₃O₂

2-(3,5-Dimethylanilino)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C18H17N3O2, CAS 306321-54-0

2-(3,5-Dimethylanilino)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 306321-54-0C₁₈H₁₇N₃O₂

2-(2-Methoxyanilino)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C17H15N3O3, CAS 303792-39-4

2-(2-Methoxyanilino)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 303792-39-4C₁₇H₁₅N₃O₃

4-Oxo-2-(4-toluidino)-4H-pyrido[1,2-a]pyrimidine-3-carboxaldehyde chemical structure, C16H13N3O2, CAS 300834-66-6

4-Oxo-2-(4-toluidino)-4H-pyrido[1,2-a]pyrimidine-3-carboxaldehyde

CAS 300834-66-6C₁₆H₁₃N₃O₂

2-Anilino-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C15H11N3O2, CAS 111680-78-5

2-Anilino-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 111680-78-5C₁₅H₁₁N₃O₂

9-Methyl-4-oxo-2-(p-tolylamino)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C17H15N3O2, CAS 300701-36-4

9-Methyl-4-oxo-2-(p-tolylamino)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 300701-36-4C₁₇H₁₅N₃O₂

4-Oxo-2-[3-(trifluoromethyl)anilino]-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H10F3N3O2, CAS 324070-10-2

4-Oxo-2-[3-(trifluoromethyl)anilino]-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 324070-10-2C₁₆H₁₀F₃N₃O₂

2-((2-Chlorophenyl)amino)-4-oxo-4H-pyrido(1,2-a)pyrimidine-3-carboxaldehyde chemical structure, C15H10ClN3O2, CAS 331948-26-6

2-((2-Chlorophenyl)amino)-4-oxo-4H-pyrido(1,2-a)pyrimidine-3-carboxaldehyde

CAS 331948-26-6C₁₅H₁₀ClN₃O₂

2-(2-Fluoroanilino)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H12FN3O2, CAS 303025-13-0

2-(2-Fluoroanilino)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 303025-13-0C₁₆H₁₂FN₃O₂

2-[(4-Ethoxyphenyl)amino]-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C18H17N3O3, CAS 610756-83-7

2-[(4-Ethoxyphenyl)amino]-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 610756-83-7C₁₈H₁₇N₃O₃

2-(4-Methoxyanilino)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C17H15N3O3, CAS 304864-99-1

2-(4-Methoxyanilino)-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 304864-99-1C₁₇H₁₅N₃O₃

2-Anilino-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H13N3O2, CAS 519047-18-8

2-Anilino-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 519047-18-8C₁₆H₁₃N₃O₂

9-Methyl-2-[(4-nitrophenyl)amino]-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H12N4O4, CAS 393837-65-5

9-Methyl-2-[(4-nitrophenyl)amino]-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde

CAS 393837-65-5C₁₆H₁₂N₄O₄

(E)-3-((sec-Butylimino)methyl)-9-methyl-2-(phenylamino)-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C20H22N4O, CAS 326007-27-6

(E)-3-((sec-Butylimino)methyl)-9-methyl-2-(phenylamino)-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 326007-27-6C₂₀H₂₂N₄O

(E)-9-Methyl-4-oxo-2-(p-tolylamino)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde O-acetyl oxime chemical structure, C19H18N4O3, CAS 302935-04-2

(E)-9-Methyl-4-oxo-2-(p-tolylamino)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde O-acetyl oxime

CAS 302935-04-2C₁₉H₁₈N₄O₃

3-[(E)-(Hydroxyimino)methyl]-2-[(4-methylphenyl)amino]-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C16H14N4O2, CAS 300839-14-9

3-[(E)-(Hydroxyimino)methyl]-2-[(4-methylphenyl)amino]-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 300839-14-9C₁₆H₁₄N₄O₂

2-[(2-Fluorophenyl)amino]-3-[(E)-(hydroxyimino)methyl]-9-methyl-4H-pyrido[1,2-a]pyrimidin-4-one chemical structure, C16H13FN4O2, CAS 303025-15-2

2-[(2-Fluorophenyl)amino]-3-[(E)-(hydroxyimino)methyl]-9-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

CAS 303025-15-2C₁₆H₁₃FN₄O₂