Murcko scaffold
1,3-Cyclohexanedione, 5-phenyl- scaffold
183 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 183
- With full pages
- 11
Scaffold SMILES
O=C1CC(=O)CC(c2ccccc2)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 183 chemicals
2,2-Dimethyl-5-phenylcyclohexane-1,3-dione
CAS 5434-98-0C14H16O2
4-(4-Carbamoyl-3,5-dioxocyclohexyl)phenyl carbamate
CAS 10223-90-2C14H14N2O5
5-(2-Methoxyphenyl)-4-methyl-6-propanoylcyclohexane-1,3-dione
CAS 16831-02-0C17H20O4
5-(4-Methoxyphenyl)cyclohexane-1,3-dione
CAS 1774-12-5C13H14O3
Dibutyl 5-carbamoyl-2-(4-hydroxyphenyl)-4,6-dioxocyclohexane-1,3-dicarboxylate
CAS 10223-92-4C23H29NO8
1,3-Cyclohexanedione, 5-phenyl-
CAS 493-72-1C12H12O2
5-(4-Methylphenyl)cyclohexane-1,3-dione
CAS 61888-37-7C13H14O2
5-(4-Hydroxyphenyl)cyclohexane-1,3-dione
CAS 91963-14-3C12H12O3
5-(3-Chlorophenyl)cyclohexane-1,3-dione
CAS 55579-71-0C12H11ClO2
5-(3,4-Dichlorophenyl)cyclohexane-1,3-dione
CAS 27463-42-9C12H10Cl2O2
![5-[4-(Trifluoromethyl)phenyl]-1,3-cyclohexanedione chemical structure, C13H11F3O2, CAS 55579-69-6](/s/HBUZHLJGLPSVNC-UHFFFAOYSA-N.svg)
5-[4-(Trifluoromethyl)phenyl]-1,3-cyclohexanedione
CAS 55579-69-6C13H11F3O2
5-(2,4-Dichlorophenyl)cyclohexane-1,3-dione
CAS 55579-70-9C12H10Cl2O2
5-(4-Nitrophenyl)cyclohexane-1,3-dione
CAS 55579-75-4C12H11NO4
5-(2,6-Dichlorophenyl)cyclohexane-1,3-dione
CAS 55579-74-3C12H10Cl2O2
![5-[2-(Trifluoromethyl)phenyl]-1,3-cyclohexanedione chemical structure, C13H11F3O2, CAS 55579-73-2](/s/YRXUINZCBBZSLH-UHFFFAOYSA-N.svg)
5-[2-(Trifluoromethyl)phenyl]-1,3-cyclohexanedione
CAS 55579-73-2C13H11F3O2
5-(2,3,4-Trimethoxyphenyl)cyclohexane-1,3-dione
CAS 119101-24-5C15H18O5
5-(4-Chlorophenyl)cyclohexane-1,3-dione
CAS 27463-38-3C12H11ClO2
5-(4-(Dimethylamino)phenyl)-1,3-cyclohexanedione
CAS 144128-70-1C14H17NO2
5-(4-Fluorophenyl)cyclohexane-1,3-dione
CAS 55579-72-1C12H11FO2
5-Mesityl-1,3-cyclohexanedione
CAS 88311-79-9C15H18O2
5-(3,4-Dimethoxyphenyl)cyclohexane-1,3-dione
CAS 190064-28-9C14H16O4
5-(2-Chlorophenyl)cyclohexane-1,3-dione
CAS 55579-68-5C12H11ClO2
5-(2-Chloro-6-fluorophenyl)-1,3-cyclohexanedione
CAS 175136-88-6C12H10ClFO2
5-(3-(Trifluoromethyl)phenyl)cyclohexane-1,3-dione
CAS 144128-67-6C13H11F3O2
- Methyl 2,4-dioxo-6-phenylcyclohexanecarboxylate80035-52-5C14H14O4
- Methyl 2-(4-methoxyphenyl)-4,6-dioxocyclohexanecarboxylate80035-51-4C15H16O5
- AG-690/340340505705-24-8C16H18O5
- 5-(4-tert-Butylphenyl)cyclohexane-1,3-dione946686-29-9C16H20O2
- 5-(3,4,5-Trimethoxyphenyl)cyclohexane-1,3-dione144128-69-8C15H18O5
- 5-(3-Methoxyphenyl)cyclohexane-1,3-dione27462-91-5C13H14O3
- 5-(4-Methylsulfanyl-phenyl)-cyclohexane-1,3-dione144128-74-5C13H14O2S
- 1,3-Cyclohexanedione, 5-(2,4-dichlorophenyl)-4-methyl-89756-75-2C13H12Cl2O2
- 5-(3-Bromophenyl)cyclohexane-1,3-dione144128-71-2C12H11BrO2
- Ethyl 2,4-dioxo-6-phenylcyclohexanecarboxylate56540-06-8C15H16O4
- 5-(2,4-Dimethoxyphenyl)cyclohexane-1,3-dione78546-99-3C14H16O4
- 2,6-Dioxo-4-phenylcyclohexane-1-carbaldehyde131248-67-4C13H12O3
- 5-(2-Fluorophenyl)cyclohexane-1,3-dione102821-72-7C12H11FO2
- (E)-{[4-(4-Chlorophenyl)-2,6-dioxocyclohexyl]methylidene}(methyl)oxidoazanium338399-41-0C14H14ClNO3
- 5-(4-Ethoxy-3-methoxyphenyl)cyclohexane-1,3-dione903440-59-5C15H18O4
- 5-(3-Ethoxyphenyl)cyclohexane-1,3-dione903471-05-6C14H16O3
- 5-(4-Isopropoxyphenyl)cyclohexane-1,3-dione762243-29-8C15H18O3
- 5-(4-Ethoxyphenyl)cyclohexane-1,3-dione762243-28-7C14H16O3
- 5-(2-Methoxyphenyl)-1,3-cyclohexanedione55579-77-6C13H14O3
- 5-(4-Isopropylphenyl)cyclohexane-1,3-dione27463-47-4C15H18O2
- 5-(3-Methylphenyl)cyclohexane-1,3-dione762243-26-5C13H14O2
- 5-(2-Methylphenyl)cyclohexane-1,3-dione239132-47-9C13H14O2
- 5-(2-Hydroxyphenyl)cyclohexane-1,3-dione78355-78-9C12H12O3
- 5-(3,5-Difluorophenyl)cyclohexane-1,3-dione928710-55-8C12H10F2O2
Related scaffolds
Same ring framework with different atoms or bond orders
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