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Murcko scaffold

2-(4-Oxo-3-(phenylsulfonyl)quinolin-1(4H)-yl)-N-phenylacetamide scaffold

471 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
30
Chemicals
471
With full pages
5
Scaffold SMILES

O=C(Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2ccccc21)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(4-Oxo-3-(phenylsulfonyl)quinolin-1(4H)-yl)-N-phenylacetamide page
Murcko scaffold O=C(Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2ccccc21)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 471 chemicals

2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(4-ethoxyphenyl)acetamide chemical structure, C26H24N2O5S, CAS 866588-71-8
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(4-ethoxyphenyl)acetamide
CAS 866588-71-8C26H24N2O5S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(4-methoxyphenyl)acetamide chemical structure, C25H22N2O5S, CAS 866588-72-9
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(4-methoxyphenyl)acetamide
CAS 866588-72-9C25H22N2O5S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(4-ethylphenyl)acetamide chemical structure, C26H24N2O4S, CAS 866588-73-0
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(4-ethylphenyl)acetamide
CAS 866588-73-0C26H24N2O4S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3-chlorophenyl)acetamide chemical structure, C24H19ClN2O4S, CAS 866588-78-5
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3-chlorophenyl)acetamide
CAS 866588-78-5C24H19ClN2O4S
2-[3-(Benzenesulfonyl)-4-oxoquinolin-1-yl]-N-(3-chloro-4-methoxyphenyl)acetamide chemical structure, C24H19ClN2O5S, CAS 866588-79-6
2-[3-(Benzenesulfonyl)-4-oxoquinolin-1-yl]-N-(3-chloro-4-methoxyphenyl)acetamide
CAS 866588-79-6C24H19ClN2O5S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(3-chloro-4-methoxyphenyl)acetamide chemical structure, C25H21ClN2O5S, CAS 866588-80-9
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(3-chloro-4-methoxyphenyl)acetamide
CAS 866588-80-9C25H21ClN2O5S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(3-chloro-4-methylphenyl)acetamide chemical structure, C25H21ClN2O4S, CAS 866588-81-0
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(3-chloro-4-methylphenyl)acetamide
CAS 866588-81-0C25H21ClN2O4S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3-methoxyphenyl)acetamide chemical structure, C25H22N2O5S, CAS 866588-82-1
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3-methoxyphenyl)acetamide
CAS 866588-82-1C25H22N2O5S
2-[3-(Benzenesulfonyl)-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3,5-dimethoxyphenyl)acetamide chemical structure, C25H22N2O6S, CAS 866588-83-2
2-[3-(Benzenesulfonyl)-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3,5-dimethoxyphenyl)acetamide
CAS 866588-83-2C25H22N2O6S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(3,5-dimethoxyphenyl)acetamide chemical structure, C26H24N2O6S, CAS 866588-85-4
2-[3-(Benzenesulfonyl)-6-methyl-4-oxoquinolin-1-yl]-N-(3,5-dimethoxyphenyl)acetamide
CAS 866588-85-4C26H24N2O6S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(2,5-dimethoxyphenyl)acetamide chemical structure, C26H24N2O6S, CAS 866588-86-5
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(2,5-dimethoxyphenyl)acetamide
CAS 866588-86-5C26H24N2O6S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3-methylphenyl)acetamide chemical structure, C25H22N2O4S, CAS 866588-87-6
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3-methylphenyl)acetamide
CAS 866588-87-6C25H22N2O4S
2-[3-(Benzenesulfonyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3-methylphenyl)acetamide chemical structure, C25H22N2O5S, CAS 866588-88-7
2-[3-(Benzenesulfonyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-1-yl]-N-(3-methylphenyl)acetamide
CAS 866588-88-7C25H22N2O5S
2-[3-(Benzenesulfonyl)-6-ethyl-4-oxoquinolin-1-yl]-N-(2-methylphenyl)acetamide chemical structure, C26H24N2O4S, CAS 866588-89-8
2-[3-(Benzenesulfonyl)-6-ethyl-4-oxoquinolin-1-yl]-N-(2-methylphenyl)acetamide
CAS 866588-89-8C26H24N2O4S
2-[3-(Benzenesulfonyl)-4-oxo-1,4-dihydroquinolin-1-yl]-N-(2,4-dimethylphenyl)acetamide chemical structure, C25H22N2O4S, CAS 866588-90-1
2-[3-(Benzenesulfonyl)-4-oxo-1,4-dihydroquinolin-1-yl]-N-(2,4-dimethylphenyl)acetamide
CAS 866588-90-1C25H22N2O4S
2-[3-(Benzenesulfonyl)-6-ethyl-4-oxoquinolin-1-yl]-N-(2,4-dimethylphenyl)acetamide chemical structure, C27H26N2O4S, CAS 866588-91-2
2-[3-(Benzenesulfonyl)-6-ethyl-4-oxoquinolin-1-yl]-N-(2,4-dimethylphenyl)acetamide
CAS 866588-91-2C27H26N2O4S
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(2-methoxyphenyl)acetamide chemical structure, C25H22N2O5S, CAS 866588-92-3
2-[3-(Benzenesulfonyl)-6-methyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-(2-methoxyphenyl)acetamide
CAS 866588-92-3C25H22N2O5S
N-(2-Methoxyphenyl)-2-[6-methyl-3-(4-methylbenzenesulfonyl)-4-oxo-1,4-dihydroquinolin-1-yl]acetamide chemical structure, C26H24N2O5S, CAS 866588-93-4
N-(2-Methoxyphenyl)-2-[6-methyl-3-(4-methylbenzenesulfonyl)-4-oxo-1,4-dihydroquinolin-1-yl]acetamide
CAS 866588-93-4C26H24N2O5S
2-[3-(Benzenesulfonyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-1-yl]-N-(2-methoxyphenyl)acetamide chemical structure, C25H22N2O6S, CAS 866588-94-5
2-[3-(Benzenesulfonyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-1-yl]-N-(2-methoxyphenyl)acetamide
CAS 866588-94-5C25H22N2O6S
2-[3-(4-Chlorophenyl)sulfonyl-6-methyl-4-oxoquinolin-1-yl]-N-phenylacetamide chemical structure, C24H19ClN2O4S, CAS 866590-90-1
2-[3-(4-Chlorophenyl)sulfonyl-6-methyl-4-oxoquinolin-1-yl]-N-phenylacetamide
CAS 866590-90-1C24H19ClN2O4S
2-[3-(Benzenesulfonyl)-6-ethyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-phenylacetamide chemical structure, C25H22N2O4S, CAS 866590-91-2
2-[3-(Benzenesulfonyl)-6-ethyl-4-oxo-1,4-dihydroquinolin-1-yl]-N-phenylacetamide
CAS 866590-91-2C25H22N2O4S
2-[3-(4-Chlorophenyl)sulfonyl-6-ethyl-4-oxoquinolin-1-yl]-N-phenylacetamide chemical structure, C25H21ClN2O4S, CAS 866590-92-3
2-[3-(4-Chlorophenyl)sulfonyl-6-ethyl-4-oxoquinolin-1-yl]-N-phenylacetamide
CAS 866590-92-3C25H21ClN2O4S
2-[3-(4-Chlorophenyl)sulfonyl-6-ethoxy-4-oxoquinolin-1-yl]-N-phenylacetamide chemical structure, C25H21ClN2O5S, CAS 866590-93-4
2-[3-(4-Chlorophenyl)sulfonyl-6-ethoxy-4-oxoquinolin-1-yl]-N-phenylacetamide
CAS 866590-93-4C25H21ClN2O5S
2-[3-(Benzenesulfonyl)-6,7-dimethoxy-4-oxoquinolin-1-yl]-N-phenylacetamide chemical structure, C25H22N2O6S, CAS 866590-94-5
2-[3-(Benzenesulfonyl)-6,7-dimethoxy-4-oxoquinolin-1-yl]-N-phenylacetamide
CAS 866590-94-5C25H22N2O6S