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Murcko scaffold

Ring system with 5 rings and 31 atoms

207 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
31
Chemicals
207
With full pages
3
Scaffold SMILES

O=C(CSc1nc(-c2ccccc2)nc2c1Cc1ccccc1O2)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nc(-c2ccccc2)nc2c1Cc1ccccc1O2)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 207 chemicals

4-[2-({7-Methyl-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamido]benzoic acid chemical structure, C27H21N3O4S, CAS 866340-62-7
4-[2-({7-Methyl-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamido]benzoic acid
CAS 866340-62-7C27H21N3O4S
3-(2-((7-Methyl-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)acetamido)benzoic acid chemical structure, C27H21N3O4S, CAS 866340-63-8
3-(2-((7-Methyl-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)acetamido)benzoic acid
CAS 866340-63-8C27H21N3O4S
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(3,4-dimethylphenyl)acetamide chemical structure, C27H22ClN3O2S, CAS 866340-66-1
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(3,4-dimethylphenyl)acetamide
CAS 866340-66-1C27H22ClN3O2S
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(3-methylphenyl)acetamide chemical structure, C26H20ClN3O2S, CAS 866340-67-2
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(3-methylphenyl)acetamide
CAS 866340-67-2C26H20ClN3O2S
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2-methylphenyl)acetamide chemical structure, C26H20ClN3O2S, CAS 866340-68-3
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2-methylphenyl)acetamide
CAS 866340-68-3C26H20ClN3O2S
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2,3-dimethylphenyl)acetamide chemical structure, C27H22ClN3O2S, CAS 866340-69-4
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2,3-dimethylphenyl)acetamide
CAS 866340-69-4C27H22ClN3O2S
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(4-fluorophenyl)acetamide chemical structure, C25H17ClFN3O2S, CAS 866340-70-7
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(4-fluorophenyl)acetamide
CAS 866340-70-7C25H17ClFN3O2S
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2-fluorophenyl)acetamide chemical structure, C25H17ClFN3O2S, CAS 866340-71-8
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2-fluorophenyl)acetamide
CAS 866340-71-8C25H17ClFN3O2S
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(3-methoxyphenyl)acetamide chemical structure, C26H20ClN3O3S, CAS 866340-72-9
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(3-methoxyphenyl)acetamide
CAS 866340-72-9C26H20ClN3O3S
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-methyl-N-phenylacetamide chemical structure, C26H20ClN3O2S, CAS 866340-73-0
2-({7-Chloro-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-methyl-N-phenylacetamide
CAS 866340-73-0C26H20ClN3O2S
2-{[2-(4-Methoxyphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C29H27N3O3S, CAS 866340-74-1
2-{[2-(4-Methoxyphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide
CAS 866340-74-1C29H27N3O3S
N-(2,3-Dimethylphenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C29H27N3O3S, CAS 866340-78-5
N-(2,3-Dimethylphenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866340-78-5C29H27N3O3S
N-(4-Fluorophenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H22FN3O3S, CAS 866340-79-6
N-(4-Fluorophenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866340-79-6C27H22FN3O3S
N-(4-Methoxyphenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H25N3O4S, CAS 866340-80-9
N-(4-Methoxyphenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866340-80-9C28H25N3O4S
N-(3-Methoxyphenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H25N3O4S, CAS 866340-81-0
N-(3-Methoxyphenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866340-81-0C28H25N3O4S
N-(2-Methylphenyl)-2-({2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide chemical structure, C26H21N3O2S, CAS 866342-13-4
N-(2-Methylphenyl)-2-({2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide
CAS 866342-13-4C26H21N3O2S
N-(4-Fluorophenyl)-2-({2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide chemical structure, C25H18FN3O2S, CAS 866342-14-5
N-(4-Fluorophenyl)-2-({2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide
CAS 866342-14-5C25H18FN3O2S
2-({9-Methoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(4-methylphenyl)acetamide chemical structure, C27H23N3O3S, CAS 866342-15-6
2-({9-Methoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(4-methylphenyl)acetamide
CAS 866342-15-6C27H23N3O3S
N-(4-Fluorophenyl)-2-({9-methoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide chemical structure, C26H20FN3O3S, CAS 866342-16-7
N-(4-Fluorophenyl)-2-({9-methoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide
CAS 866342-16-7C26H20FN3O3S
2-((9-Methoxy-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(4-methoxyphenyl)acetamide chemical structure, C27H23N3O4S, CAS 866342-17-8
2-((9-Methoxy-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(4-methoxyphenyl)acetamide
CAS 866342-17-8C27H23N3O4S
2-({9-Ethoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-phenylacetamide chemical structure, C27H23N3O3S, CAS 866342-18-9
2-({9-Ethoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-phenylacetamide
CAS 866342-18-9C27H23N3O3S
N-(4-Methoxyphenyl)-2-{[2-(4-methoxyphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H23N3O4S, CAS 866344-30-1
N-(4-Methoxyphenyl)-2-{[2-(4-methoxyphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866344-30-1C27H23N3O4S
2-({9-Ethoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(4-methylphenyl)acetamide chemical structure, C28H25N3O3S, CAS 866348-83-6
2-({9-Ethoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(4-methylphenyl)acetamide
CAS 866348-83-6C28H25N3O3S
2-({9-Ethoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2-methylphenyl)acetamide chemical structure, C28H25N3O3S, CAS 866348-84-7
2-({9-Ethoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2-methylphenyl)acetamide
CAS 866348-84-7C28H25N3O3S