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Murcko scaffold

Ring system with 5 rings and 31 atoms

207 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
31
Chemicals
207
With full pages
3
Scaffold SMILES

O=C(CSc1nc(-c2ccccc2)nc2c1Cc1ccccc1O2)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nc(-c2ccccc2)nc2c1Cc1ccccc1O2)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 207 chemicals

N-(2,6-Dimethylphenyl)-2-{[7-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C29H27N3O2S, CAS 866726-56-9
N-(2,6-Dimethylphenyl)-2-{[7-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866726-56-9C29H27N3O2S
2-{[7-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C30H29N3O2S, CAS 866726-58-1
2-{[7-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide
CAS 866726-58-1C30H29N3O2S
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-phenylacetamide chemical structure, C27H23N3O2S, CAS 866726-62-7
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-phenylacetamide
CAS 866726-62-7C27H23N3O2S
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(4-methylphenyl)acetamide chemical structure, C28H25N3O2S, CAS 866726-64-9
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(4-methylphenyl)acetamide
CAS 866726-64-9C28H25N3O2S
N-(3,4-Dimethylphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C29H27N3O2S, CAS 866726-66-1
N-(3,4-Dimethylphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866726-66-1C29H27N3O2S
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(3-methylphenyl)acetamide chemical structure, C28H25N3O2S, CAS 866726-68-3
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(3-methylphenyl)acetamide
CAS 866726-68-3C28H25N3O2S
N-(2,6-Dimethylphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C29H27N3O2S, CAS 866726-70-7
N-(2,6-Dimethylphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866726-70-7C29H27N3O2S
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C30H29N3O2S, CAS 866726-72-9
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide
CAS 866726-72-9C30H29N3O2S
N-(2,3-Dimethylphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C29H27N3O2S, CAS 866726-74-1
N-(2,3-Dimethylphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866726-74-1C29H27N3O2S
N-(4-Fluorophenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H22FN3O2S, CAS 866726-76-3
N-(4-Fluorophenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866726-76-3C27H22FN3O2S
N-(2-Methoxyphenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H25N3O4S, CAS 866729-78-4
N-(2-Methoxyphenyl)-2-{[2-(4-methoxyphenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866729-78-4C28H25N3O4S
N-(3,4-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H22FN3O2S, CAS 866729-80-8
N-(3,4-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866729-80-8C27H22FN3O2S
2-{[2-(4-Fluorophenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(3-methylphenyl)acetamide chemical structure, C26H20FN3O2S, CAS 866729-81-9
2-{[2-(4-Fluorophenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(3-methylphenyl)acetamide
CAS 866729-81-9C26H20FN3O2S
2-{[2-(4-Fluorophenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide chemical structure, C26H20FN3O2S, CAS 866729-82-0
2-{[2-(4-Fluorophenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide
CAS 866729-82-0C26H20FN3O2S
2-{[2-(4-Fluorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-phenylacetamide chemical structure, C26H20FN3O2S, CAS 866729-83-1
2-{[2-(4-Fluorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-phenylacetamide
CAS 866729-83-1C26H20FN3O2S
N-(3,4-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H24FN3O2S, CAS 866729-84-2
N-(3,4-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866729-84-2C28H24FN3O2S
2-{[2-(4-Fluorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(3-methylphenyl)acetamide chemical structure, C27H22FN3O2S, CAS 866729-85-3
2-{[2-(4-Fluorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(3-methylphenyl)acetamide
CAS 866729-85-3C27H22FN3O2S
N-(4-Chlorophenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C26H19ClFN3O2S, CAS 866729-86-4
N-(4-Chlorophenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866729-86-4C26H19ClFN3O2S
N-(4-Fluorophenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C26H19F2N3O2S, CAS 866729-87-5
N-(4-Fluorophenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866729-87-5C26H19F2N3O2S
N-(4-Chlorophenyl)-2-{[7-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H22ClN3O2S, CAS 866807-72-9
N-(4-Chlorophenyl)-2-{[7-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866807-72-9C27H22ClN3O2S
N-(4-Chlorophenyl)-2-({7-methyl-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide chemical structure, C26H20ClN3O2S, CAS 866811-21-4
N-(4-Chlorophenyl)-2-({7-methyl-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide
CAS 866811-21-4C26H20ClN3O2S
2-{[2-(4-Methoxyphenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-methyl-N-phenylacetamide chemical structure, C28H25N3O3S, CAS 866811-24-7
2-{[2-(4-Methoxyphenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-methyl-N-phenylacetamide
CAS 866811-24-7C28H25N3O3S
2-{[2-(4-Fluorophenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide chemical structure, C28H24FN3O2S, CAS 866811-25-8
2-{[2-(4-Fluorophenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(2,4,6-trimethylphenyl)acetamide
CAS 866811-25-8C28H24FN3O2S
N-(2,3-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H22FN3O2S, CAS 866811-26-9
N-(2,3-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866811-26-9C27H22FN3O2S