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Murcko scaffold

Ring system with 5 rings and 31 atoms

207 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
31
Chemicals
207
With full pages
3
Scaffold SMILES

O=C(CSc1nc(-c2ccccc2)nc2c1Cc1ccccc1O2)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nc(-c2ccccc2)nc2c1Cc1ccccc1O2)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 207 chemicals

2-{[2-(4-Fluorophenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(4-methoxyphenyl)acetamide chemical structure, C26H20FN3O3S, CAS 872200-00-5
2-{[2-(4-Fluorophenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(4-methoxyphenyl)acetamide
CAS 872200-00-5C26H20FN3O3S
N-(3-Chlorophenyl)-2-({9-methoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide chemical structure, C26H20ClN3O3S, CAS 866842-66-2
N-(3-Chlorophenyl)-2-({9-methoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide
CAS 866842-66-2C26H20ClN3O3S
N-(2-Fluorophenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H22FN3O2S, CAS 866842-70-8
N-(2-Fluorophenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866842-70-8C27H22FN3O2S
3-[[2-[[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl]acetyl]amino]benzoic acid chemical structure, C28H23N3O4S, CAS 866842-71-9
3-[[2-[[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl]acetyl]amino]benzoic acid
CAS 866842-71-9C28H23N3O4S
N-(3-Methoxyphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H25N3O3S, CAS 866842-73-1
N-(3-Methoxyphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866842-73-1C28H25N3O3S
N-(2-Methoxyphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H25N3O3S, CAS 866842-74-2
N-(2-Methoxyphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866842-74-2C28H25N3O3S
N-(3,5-Dimethylphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C29H27N3O2S, CAS 866842-75-3
N-(3,5-Dimethylphenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866842-75-3C29H27N3O2S
2-{[2-(4-Chlorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide chemical structure, C27H22ClN3O2S, CAS 866844-96-4
2-{[2-(4-Chlorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide
CAS 866844-96-4C27H22ClN3O2S
2-({2-Phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C26H18F3N3O2S, CAS 866847-21-4
2-({2-Phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 866847-21-4C26H18F3N3O2S
N-(3,5-Dimethoxyphenyl)-2-({2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide chemical structure, C27H23N3O4S, CAS 866847-22-5
N-(3,5-Dimethoxyphenyl)-2-({2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)acetamide
CAS 866847-22-5C27H23N3O4S
2-((7-Methyl-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(3-(methylthio)phenyl)acetamide chemical structure, C27H23N3O2S2, CAS 866848-15-9
2-((7-Methyl-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(3-(methylthio)phenyl)acetamide
CAS 866848-15-9C27H23N3O2S2
2-({9-Ethoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2-methoxyphenyl)acetamide chemical structure, C28H25N3O4S, CAS 866848-16-0
2-({9-Ethoxy-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-(2-methoxyphenyl)acetamide
CAS 866848-16-0C28H25N3O4S
N-(4-Ethoxyphenyl)-2-{[2-(4-methoxyphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H25N3O4S, CAS 866848-17-1
N-(4-Ethoxyphenyl)-2-{[2-(4-methoxyphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866848-17-1C28H25N3O4S
N-(4-Methylphenyl)-2-{[2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H23N3O2S, CAS 866864-69-9
N-(4-Methylphenyl)-2-{[2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866864-69-9C27H23N3O2S
N-(2-Methylphenyl)-2-{[2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H23N3O2S, CAS 866864-70-2
N-(2-Methylphenyl)-2-{[2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866864-70-2C27H23N3O2S
N-(2,3-Dimethylphenyl)-2-{[2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H25N3O2S, CAS 866864-71-3
N-(2,3-Dimethylphenyl)-2-{[2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866864-71-3C28H25N3O2S
N-(3,5-Dimethylphenyl)-2-{[2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H25N3O2S, CAS 866864-72-4
N-(3,5-Dimethylphenyl)-2-{[2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866864-72-4C28H25N3O2S
N-(3,4-Dimethylphenyl)-2-((2-(4-(methylthio)phenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)acetamide chemical structure, C28H25N3O2S2, CAS 866864-73-5
N-(3,4-Dimethylphenyl)-2-((2-(4-(methylthio)phenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)acetamide
CAS 866864-73-5C28H25N3O2S2
N-(2,6-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H24FN3O2S, CAS 866864-75-7
N-(2,6-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866864-75-7C28H24FN3O2S
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide chemical structure, C28H25N3O2S, CAS 866864-76-8
2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide
CAS 866864-76-8C28H25N3O2S
N-(2-Chlorophenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C27H22ClN3O2S, CAS 866864-77-9
N-(2-Chlorophenyl)-2-{[9-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}acetamide
CAS 866864-77-9C27H22ClN3O2S
2-{[2-(4-Fluorophenyl)-9-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-methyl-N-phenylacetamide chemical structure, C27H22FN3O2S, CAS 866870-94-2
2-{[2-(4-Fluorophenyl)-9-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}-N-methyl-N-phenylacetamide
CAS 866870-94-2C27H22FN3O2S
2-({9-Methyl-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-phenylacetamide chemical structure, C26H21N3O2S, CAS 866871-02-5
2-({9-Methyl-2-phenyl-5H-chromeno[2,3-D]pyrimidin-4-YL}sulfanyl)-N-phenylacetamide
CAS 866871-02-5C26H21N3O2S
2-((9-Methyl-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(p-tolyl)acetamide chemical structure, C27H23N3O2S, CAS 866871-04-7
2-((9-Methyl-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(p-tolyl)acetamide
CAS 866871-04-7C27H23N3O2S