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Murcko scaffold

Ring system with 5 rings and 31 atoms

207 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
31
Chemicals
207
With full pages
3
Scaffold SMILES

O=C(CSc1nc(-c2ccccc2)nc2c1Cc1ccccc1O2)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nc(-c2ccccc2)nc2c1Cc1ccccc1O2)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 207 of 207 chemicals

2-((7-Methyl-2-(p-tolyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(p-tolyl)acetamide chemical structure, C28H25N3O2S, CAS 895641-92-6
2-((7-Methyl-2-(p-tolyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(p-tolyl)acetamide
CAS 895641-92-6C28H25N3O2S
N-(3,4-Dimethylphenyl)-2-{[7-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C29H27N3O2S, CAS 895641-96-0
N-(3,4-Dimethylphenyl)-2-{[7-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 895641-96-0C29H27N3O2S
N-(3,5-Dimethylphenyl)-2-((7-methyl-2-(p-tolyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)acetamide chemical structure, C29H27N3O2S, CAS 895642-00-9
N-(3,5-Dimethylphenyl)-2-((7-methyl-2-(p-tolyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)acetamide
CAS 895642-00-9C29H27N3O2S
N-(4-Ethoxyphenyl)-2-{[7-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C29H27N3O3S, CAS 895642-04-3
N-(4-Ethoxyphenyl)-2-{[7-methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 895642-04-3C29H27N3O3S
2-((2-(4-Chlorophenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(3-methoxyphenyl)acetamide chemical structure, C26H20ClN3O3S, CAS 895646-46-5
2-((2-(4-Chlorophenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(3-methoxyphenyl)acetamide
CAS 895646-46-5C26H20ClN3O3S
2-((2-(4-Fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(p-tolyl)acetamide chemical structure, C27H22FN3O2S, CAS 895646-68-1
2-((2-(4-Fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(p-tolyl)acetamide
CAS 895646-68-1C27H22FN3O2S
2-((2-(4-Fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(o-tolyl)acetamide chemical structure, C27H22FN3O2S, CAS 895646-72-7
2-((2-(4-Fluorophenyl)-7-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(o-tolyl)acetamide
CAS 895646-72-7C27H22FN3O2S
N-(2-Fluorophenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C26H19F2N3O2S, CAS 895646-76-1
N-(2-Fluorophenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 895646-76-1C26H19F2N3O2S
N-(3,5-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide chemical structure, C28H24FN3O2S, CAS 895646-81-8
N-(3,5-Dimethylphenyl)-2-{[2-(4-fluorophenyl)-7-methyl-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamide
CAS 895646-81-8C28H24FN3O2S
2-((2-(4-Chlorophenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(2,3-dimethylphenyl)acetamide chemical structure, C27H22ClN3O2S, CAS 895640-01-4
2-((2-(4-Chlorophenyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(2,3-dimethylphenyl)acetamide
CAS 895640-01-4C27H22ClN3O2S
N-(2-Chlorophenyl)-2-((2-(p-tolyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)acetamide chemical structure, C26H20ClN3O2S, CAS 899357-71-2
N-(2-Chlorophenyl)-2-((2-(p-tolyl)-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)acetamide
CAS 899357-71-2C26H20ClN3O2S
2-((9-Methyl-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(3-(methylthio)phenyl)acetamide chemical structure, C27H23N3O2S2, CAS 899357-72-3
2-((9-Methyl-2-phenyl-5H-chromeno[2,3-d]pyrimidin-4-yl)thio)-N-(3-(methylthio)phenyl)acetamide
CAS 899357-72-3C27H23N3O2S2
2-{[2-(4-Chlorophenyl)-9-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide chemical structure, C27H22ClN3O2S, CAS 902621-26-5
2-{[2-(4-Chlorophenyl)-9-methyl-5H-chromeno[2,3-d]pyrimidin-4-yl]sulfanyl}-N-(2-methylphenyl)acetamide
CAS 902621-26-5C27H22ClN3O2S
4-(2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamido)benzoic acid chemical structure, C28H23N3O4S, CAS 902289-94-5
4-(2-{[9-Methyl-2-(4-methylphenyl)-5H-chromeno[2,3-D]pyrimidin-4-yl]sulfanyl}acetamido)benzoic acid
CAS 902289-94-5C28H23N3O4S
UCK2 Inhibitor-1 chemical structure, C27H21N3O4S, CAS 902289-98-9
UCK2 Inhibitor-1
CAS 902289-98-9C27H21N3O4S