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Murcko scaffold

2-(1H-1,2,4-Triazol-5-yl)pyrazine scaffold

27 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 27
With full pages: 5

Scaffold SMILES

c1cnc(-c2nnc[nH]2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(1H-1,2,4-Triazol-5-yl)pyrazine page

Murcko scaffold c1cnc(-c2nnc[nH]2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

2-[(4-Methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C9H10N6OS, CAS 799262-82-1

2-[(4-Methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide

CAS 799262-82-1C₉H₁₀N₆OS

Methylethyl 2-(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-ylthio)acetate chemical structure, C12H15N5O2S, CAS 573947-07-6

Methylethyl 2-(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-ylthio)acetate

CAS 573947-07-6C₁₂H₁₅N₅O₂S

1-{[4-Ethyl-5-(2-pyrazinyl)-4H-1,2,4-triazol-3-yl]thio}-3,3-dimethyl-2-butanone chemical structure, C14H19N5OS, CAS 586982-86-7

1-{[4-Ethyl-5-(2-pyrazinyl)-4H-1,2,4-triazol-3-yl]thio}-3,3-dimethyl-2-butanone

CAS 586982-86-7C₁₄H₁₉N₅OS

3,3-Dimethyl-1-{[4-methyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}butan-2-one chemical structure, C13H17N5OS, CAS 578732-67-9

3,3-Dimethyl-1-{[4-methyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}butan-2-one

CAS 578732-67-9C₁₃H₁₇N₅OS

2-{[4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C10H12N6OS, CAS 579441-70-6

2-{[4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 579441-70-6C₁₀H₁₂N₆OS

2-{[4-(Prop-2-en-1-yl)-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C11H12N6OS, CAS 579445-99-1

2-{[4-(Prop-2-en-1-yl)-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 579445-99-1C₁₁H₁₂N₆OS

N-tert-Butyl-2-{[4-methyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C13H18N6OS, CAS 731788-61-7

N-tert-Butyl-2-{[4-methyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 731788-61-7C₁₃H₁₈N₆OS

Ethyl 2-[2-(4-prop-2-enyl-5-pyrazin-2-yl-1,2,4-triazol-3-ylthio)acetylamino]ac etate chemical structure, C15H18N6O3S, CAS 578744-34-0

Ethyl 2-[2-(4-prop-2-enyl-5-pyrazin-2-yl-1,2,4-triazol-3-ylthio)acetylamino]ac etate

CAS 578744-34-0C₁₅H₁₈N₆O₃S

5-Amino-3-(2-pyrazinyl)-1H-1,2,4-triazole chemical structure, C6H6N6, CAS 502685-78-1

5-Amino-3-(2-pyrazinyl)-1H-1,2,4-triazole

CAS 502685-78-1C₆H₆N₆

2-(1-Methyl-1H-1,2,4-triazol-3-yl)pyrazine chemical structure, C7H7N5, CAS 130612-32-7

2-(1-Methyl-1H-1,2,4-triazol-3-yl)pyrazine

CAS 130612-32-7C₇H₇N₅

2-(1H-1,2,4-Triazol-5-yl)pyrazine chemical structure, C6H5N5, CAS 130612-31-6

2-(1H-1,2,4-Triazol-5-yl)pyrazine

CAS 130612-31-6C₆H₅N₅

1-(3-(Pyrazin-2-yl)-1H-1,2,4-triazol-5-yl)ethan-1-amine chemical structure, C8H10N6, CAS 958717-43-6

1-(3-(Pyrazin-2-yl)-1H-1,2,4-triazol-5-yl)ethan-1-amine

CAS 958717-43-6C₈H₁₀N₆

2-(3-Methyl-1H-1,2,4-triazol-5-yl)pyrazine chemical structure, C7H7N5, CAS 130612-33-8

2-(3-Methyl-1H-1,2,4-triazol-5-yl)pyrazine

CAS 130612-33-8C₇H₇N₅

2-(3-(Pyrazin-2-yl)-1H-1,2,4-triazol-5-yl)acetic acid chemical structure, C8H7N5O2, CAS 1087648-44-9

2-(3-(Pyrazin-2-yl)-1H-1,2,4-triazol-5-yl)acetic acid

CAS 1087648-44-9C₈H₇N₅O₂

Ethyl 2-(3-(pyrazin-2-yl)-1H-1,2,4-triazol-5-yl)acetate chemical structure, C10H11N5O2, CAS 1087648-36-9

Ethyl 2-(3-(pyrazin-2-yl)-1H-1,2,4-triazol-5-yl)acetate

CAS 1087648-36-9C₁₀H₁₁N₅O₂

2-Methyl-5-(3-methyl-1H-1,2,4-triazol-5-yl)pyrazine chemical structure, C8H9N5, CAS 1094688-02-4

2-Methyl-5-(3-methyl-1H-1,2,4-triazol-5-yl)pyrazine

CAS 1094688-02-4C₈H₉N₅

[(5-Pyrazin-2-yl-4H-1,2,4-triazol-3-yl)methyl]-amine dihydrochloride chemical structure, C7H10Cl2N6, CAS 1332531-61-9

[(5-Pyrazin-2-yl-4H-1,2,4-triazol-3-yl)methyl]-amine dihydrochloride

CAS 1332531-61-9C₇H₁₀Cl₂N₆

Ethyl 3-(pyrazin-2-yl)-1H-1,2,4-triazole-5-carboxylate chemical structure, C9H9N5O2, CAS 1344335-45-0

Ethyl 3-(pyrazin-2-yl)-1H-1,2,4-triazole-5-carboxylate

CAS 1344335-45-0C₉H₉N₅O₂

2-(5-tert-Butyl-4H-1,2,4-triazol-3-yl)pyrazine chemical structure, C10H13N5, CAS 1346229-64-8

2-(5-tert-Butyl-4H-1,2,4-triazol-3-yl)pyrazine

CAS 1346229-64-8C₁₀H₁₃N₅

1-[3-(2-Pyrazinyl)-1H-1,2,4-triazol-5-yl]methanamine dihydrochloride hydrate chemical structure, C7H12Cl2N6O, CAS 1306739-23-0

1-[3-(2-Pyrazinyl)-1H-1,2,4-triazol-5-yl]methanamine dihydrochloride hydrate

CAS 1306739-23-0C₇H₁₂Cl₂N₆O

[5-(Pyrazin-2-yl)-1H-1,2,4-triazol-3-yl]methanol chemical structure, C7H7N5O, CAS 1506589-76-9

[5-(Pyrazin-2-yl)-1H-1,2,4-triazol-3-yl]methanol

CAS 1506589-76-9C₇H₇N₅O

2-Methyl-1-(3-(pyrazin-2-yl)-1H-1,2,4-triazol-5-yl)propan-1-amine chemical structure, C10H14N6, CAS 1707586-60-4

2-Methyl-1-(3-(pyrazin-2-yl)-1H-1,2,4-triazol-5-yl)propan-1-amine

CAS 1707586-60-4C₁₀H₁₄N₆

4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazole-3-sulfonyl chloride chemical structure, C8H8ClN5O2S, CAS 1566375-54-9

4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazole-3-sulfonyl chloride

CAS 1566375-54-9C₈H₈ClN₅O₂S

4-Methyl-5-(pyrazin-2-yl)-4H-1,2,4-triazole-3-sulfonyl chloride chemical structure, C7H6ClN5O2S, CAS 1566417-70-6

4-Methyl-5-(pyrazin-2-yl)-4H-1,2,4-triazole-3-sulfonyl chloride

CAS 1566417-70-6C₇H₆ClN₅O₂S