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Murcko scaffold

(Pyridin-3-yl)(pyrrolidin-1-yl)methanone scaffold

186 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
186
With full pages
4
Scaffold SMILES

O=C(c1cccnc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (Pyridin-3-yl)(pyrrolidin-1-yl)methanone page
Murcko scaffold O=C(c1cccnc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 186 chemicals

(3R)-1-(6-Fluoropyridine-3-carbonyl)pyrrolidin-3-ol chemical structure, C10H11FN2O2, CAS 1689852-20-7
(3R)-1-(6-Fluoropyridine-3-carbonyl)pyrrolidin-3-ol
CAS 1689852-20-7C10H11FN2O2
1-(2-Chloronicotinoyl)pyrrolidine-3-carboxylic acid chemical structure, C11H11ClN2O3, CAS 1571803-16-1
1-(2-Chloronicotinoyl)pyrrolidine-3-carboxylic acid
CAS 1571803-16-1C11H11ClN2O3
(2-Chloro-5-fluoropyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C10H10ClFN2O, CAS 1694386-19-0
(2-Chloro-5-fluoropyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 1694386-19-0C10H10ClFN2O
(5-Fluoropyridin-3-yl)(3-hydroxypyrrolidin-1-yl)methanone chemical structure, C10H11FN2O2, CAS 1564650-87-8
(5-Fluoropyridin-3-yl)(3-hydroxypyrrolidin-1-yl)methanone
CAS 1564650-87-8C10H11FN2O2
(2-Fluoropyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C10H11FN2O, CAS 1704023-36-8
(2-Fluoropyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 1704023-36-8C10H11FN2O
(3R)-1-(2-Fluoropyridine-3-carbonyl)pyrrolidin-3-ol chemical structure, C10H11FN2O2, CAS 1690017-50-5
(3R)-1-(2-Fluoropyridine-3-carbonyl)pyrrolidin-3-ol
CAS 1690017-50-5C10H11FN2O2
1-(2-Fluoropyridine-3-carbonyl)pyrrolidin-3-ol chemical structure, C10H11FN2O2, CAS 1700510-55-9
1-(2-Fluoropyridine-3-carbonyl)pyrrolidin-3-ol
CAS 1700510-55-9C10H11FN2O2
1-[2-Methyl-1-(pyridine-3-carbonyl)pyrrolidin-2-yl]methanamine chemical structure, C12H17N3O, CAS 1897542-11-8
1-[2-Methyl-1-(pyridine-3-carbonyl)pyrrolidin-2-yl]methanamine
CAS 1897542-11-8C12H17N3O
5,5-Dimethyl-1-(pyridine-3-carbonyl)pyrrolidin-3-amine chemical structure, C12H17N3O, CAS 1893760-26-3
5,5-Dimethyl-1-(pyridine-3-carbonyl)pyrrolidin-3-amine
CAS 1893760-26-3C12H17N3O
3-Fluoro-5-(pyrrolidine-1-carbonyl)pyridine chemical structure, C10H11FN2O, CAS 1565473-37-1
3-Fluoro-5-(pyrrolidine-1-carbonyl)pyridine
CAS 1565473-37-1C10H11FN2O
1-(5-Fluoronicotinoyl)pyrrolidine-3-carboxylic acid chemical structure, C11H11FN2O3, CAS 1707412-72-3
1-(5-Fluoronicotinoyl)pyrrolidine-3-carboxylic acid
CAS 1707412-72-3C11H11FN2O3
(3-Aminopyrrolidin-1-yl)(5-fluoropyridin-3-yl)methanone chemical structure, C10H12FN3O, CAS 1566850-25-6
(3-Aminopyrrolidin-1-yl)(5-fluoropyridin-3-yl)methanone
CAS 1566850-25-6C10H12FN3O
(5-Fluoropyridin-3-yl)(3-(hydroxymethyl)pyrrolidin-1-yl)methanone chemical structure, C11H13FN2O2, CAS 1566215-44-8
(5-Fluoropyridin-3-yl)(3-(hydroxymethyl)pyrrolidin-1-yl)methanone
CAS 1566215-44-8C11H13FN2O2
5-Bromo-2-methyl-3-[(pyrrolidin-1-yl)carbonyl]pyridine chemical structure, C11H13BrN2O, CAS 1801907-33-4
5-Bromo-2-methyl-3-[(pyrrolidin-1-yl)carbonyl]pyridine
CAS 1801907-33-4C11H13BrN2O
1-(1-(5-Bromonicotinoyl)pyrrolidin-3-yl)ethanone chemical structure, C12H13BrN2O2, CAS 2034414-83-8
1-(1-(5-Bromonicotinoyl)pyrrolidin-3-yl)ethanone
CAS 2034414-83-8C12H13BrN2O2
1-(1-(6-(Trifluoromethyl)nicotinoyl)pyrrolidin-3-yl)ethanone chemical structure, C13H13F3N2O2, CAS 2034463-04-0
1-(1-(6-(Trifluoromethyl)nicotinoyl)pyrrolidin-3-yl)ethanone
CAS 2034463-04-0C13H13F3N2O2
(2-Ethoxypyridin-3-yl)(3-hydroxypyrrolidin-1-yl)methanone chemical structure, C12H16N2O3, CAS 2098081-04-8
(2-Ethoxypyridin-3-yl)(3-hydroxypyrrolidin-1-yl)methanone
CAS 2098081-04-8C12H16N2O3
(3-Aminopyrrolidin-1-yl)(2-ethoxypyridin-3-yl)methanone chemical structure, C12H17N3O2, CAS 2098032-24-5
(3-Aminopyrrolidin-1-yl)(2-ethoxypyridin-3-yl)methanone
CAS 2098032-24-5C12H17N3O2
(3-Aminopyrrolidin-1-yl)(6-chloropyridin-3-yl)methanone chemical structure, C10H12ClN3O, CAS 1586174-52-8
(3-Aminopyrrolidin-1-yl)(6-chloropyridin-3-yl)methanone
CAS 1586174-52-8C10H12ClN3O
(3-Aminopyrrolidin-1-yl)(6-methoxypyridin-3-yl)methanone chemical structure, C11H15N3O2, CAS 2098081-88-8
(3-Aminopyrrolidin-1-yl)(6-methoxypyridin-3-yl)methanone
CAS 2098081-88-8C11H15N3O2
(6-Ethoxypyridin-3-yl)(3-hydroxypyrrolidin-1-yl)methanone chemical structure, C12H16N2O3, CAS 2098046-58-1
(6-Ethoxypyridin-3-yl)(3-hydroxypyrrolidin-1-yl)methanone
CAS 2098046-58-1C12H16N2O3
(3-Aminopyrrolidin-1-yl)(6-ethoxypyridin-3-yl)methanone chemical structure, C12H17N3O2, CAS 2098082-29-0
(3-Aminopyrrolidin-1-yl)(6-ethoxypyridin-3-yl)methanone
CAS 2098082-29-0C12H17N3O2
5-(Pyrrolidine-1-carbonyl)pyridin-2-amine hydrochloride chemical structure, C10H14ClN3O, CAS 1803607-75-1
5-(Pyrrolidine-1-carbonyl)pyridin-2-amine hydrochloride
CAS 1803607-75-1C10H14ClN3O
3-Bromo-2-chloro-5-[3-(ethoxymethyl)pyrrolidine-1-carbonyl]pyridine chemical structure, C13H16BrClN2O2, CAS 2094394-43-9
3-Bromo-2-chloro-5-[3-(ethoxymethyl)pyrrolidine-1-carbonyl]pyridine
CAS 2094394-43-9C13H16BrClN2O2