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Murcko scaffold

(Pyridin-3-yl)(pyrrolidin-1-yl)methanone scaffold

186 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
186
With full pages
4
Scaffold SMILES

O=C(c1cccnc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (Pyridin-3-yl)(pyrrolidin-1-yl)methanone page
Murcko scaffold O=C(c1cccnc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 186 of 186 chemicals

(2-Fluoro-5-methylpyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C11H13FN2O, CAS 2404734-44-5
(2-Fluoro-5-methylpyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 2404734-44-5C11H13FN2O
N-[[2-Methyl-1-(pyridine-3-carbonyl)pyrrolidin-2-yl]methyl]prop-2-enamide chemical structure, C15H19N3O2, CAS 2411254-50-5
N-[[2-Methyl-1-(pyridine-3-carbonyl)pyrrolidin-2-yl]methyl]prop-2-enamide
CAS 2411254-50-5C15H19N3O2
(2E)-4-(Dimethylamino)-N-{[2-methyl-1-(pyridine-3-carbonyl)pyrrolidin-2-yl]methyl}but-2-enamide chemical structure, C18H26N4O2, CAS 2411324-45-1
(2E)-4-(Dimethylamino)-N-{[2-methyl-1-(pyridine-3-carbonyl)pyrrolidin-2-yl]methyl}but-2-enamide
CAS 2411324-45-1C18H26N4O2
(5-Bromo-2-fluoropyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C10H10BrFN2O, CAS 2161761-92-6
(5-Bromo-2-fluoropyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 2161761-92-6C10H10BrFN2O
(5-Ethynylpyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C12H12N2O, CAS 2740358-04-5
(5-Ethynylpyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 2740358-04-5C12H12N2O
3-(2,2-Diethylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine chemical structure, C14H19FN2O4S, CAS 2418662-93-6
3-(2,2-Diethylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine
CAS 2418662-93-6C14H19FN2O4S
3-Fluorosulfonyloxy-5-[(2S)-2-methylpyrrolidine-1-carbonyl]pyridine chemical structure, C11H13FN2O4S, CAS 2418595-39-6
3-Fluorosulfonyloxy-5-[(2S)-2-methylpyrrolidine-1-carbonyl]pyridine
CAS 2418595-39-6C11H13FN2O4S
3-Fluorosulfonyloxy-5-(2,2,5-trimethylpyrrolidine-1-carbonyl)pyridine chemical structure, C13H17FN2O4S, CAS 2418708-34-4
3-Fluorosulfonyloxy-5-(2,2,5-trimethylpyrrolidine-1-carbonyl)pyridine
CAS 2418708-34-4C13H17FN2O4S
3-Fluorosulfonyloxy-5-(3-propan-2-ylpyrrolidine-1-carbonyl)pyridine chemical structure, C13H17FN2O4S, CAS 2418643-68-0
3-Fluorosulfonyloxy-5-(3-propan-2-ylpyrrolidine-1-carbonyl)pyridine
CAS 2418643-68-0C13H17FN2O4S
3-(2-tert-Butylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine chemical structure, C14H19FN2O4S, CAS 2418728-18-2
3-(2-tert-Butylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine
CAS 2418728-18-2C14H19FN2O4S
3-[(2S)-2-Carbamoyl-2-methylpyrrolidine-1-carbonyl]-5-fluorosulfonyloxypyridine chemical structure, C12H14FN3O5S, CAS 2418594-58-6
3-[(2S)-2-Carbamoyl-2-methylpyrrolidine-1-carbonyl]-5-fluorosulfonyloxypyridine
CAS 2418594-58-6C12H14FN3O5S
Methyl (2R)-1-(5-fluorosulfonyloxypyridine-3-carbonyl)pyrrolidine-2-carboxylate chemical structure, C12H13FN2O6S, CAS 2418593-65-2
Methyl (2R)-1-(5-fluorosulfonyloxypyridine-3-carbonyl)pyrrolidine-2-carboxylate
CAS 2418593-65-2C12H13FN2O6S
3-Fluorosulfonyloxy-5-(4-methoxy-3,3-dimethylpyrrolidine-1-carbonyl)pyridine chemical structure, C13H17FN2O5S, CAS 2418650-12-9
3-Fluorosulfonyloxy-5-(4-methoxy-3,3-dimethylpyrrolidine-1-carbonyl)pyridine
CAS 2418650-12-9C13H17FN2O5S
3-Fluorosulfonyloxy-5-(3-methoxy-2,2-dimethylpyrrolidine-1-carbonyl)pyridine chemical structure, C13H17FN2O5S, CAS 2418650-15-2
3-Fluorosulfonyloxy-5-(3-methoxy-2,2-dimethylpyrrolidine-1-carbonyl)pyridine
CAS 2418650-15-2C13H17FN2O5S
3-(4,4-Difluoro-2-methylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine chemical structure, C11H11F3N2O4S, CAS 2418662-15-2
3-(4,4-Difluoro-2-methylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine
CAS 2418662-15-2C11H11F3N2O4S
3-(3-tert-Butylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine chemical structure, C14H19FN2O4S, CAS 2418677-47-9
3-(3-tert-Butylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine
CAS 2418677-47-9C14H19FN2O4S
3-(3-Cyano-3-fluoropyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine chemical structure, C11H9F2N3O4S, CAS 2418677-40-2
3-(3-Cyano-3-fluoropyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine
CAS 2418677-40-2C11H9F2N3O4S
3-(3,3-Diethylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine chemical structure, C14H19FN2O4S, CAS 2418719-74-9
3-(3,3-Diethylpyrrolidine-1-carbonyl)-5-fluorosulfonyloxypyridine
CAS 2418719-74-9C14H19FN2O4S
(6-Chloro-2-methoxypyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C11H13ClN2O2, CAS 2829061-38-1
(6-Chloro-2-methoxypyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 2829061-38-1C11H13ClN2O2
(6-Chloro-4-methoxypyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C11H13ClN2O2, CAS 2806489-27-8
(6-Chloro-4-methoxypyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 2806489-27-8C11H13ClN2O2
(2-Chloro-5-(trifluoromethyl)pyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C11H10ClF3N2O, CAS 2809510-17-4
(2-Chloro-5-(trifluoromethyl)pyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 2809510-17-4C11H10ClF3N2O
(2-Chloro-5-(trifluoromethyl)pyridin-3-yl)(3,3-difluoropyrrolidin-1-yl)methanone chemical structure, C11H8ClF5N2O, CAS 2804137-18-4
(2-Chloro-5-(trifluoromethyl)pyridin-3-yl)(3,3-difluoropyrrolidin-1-yl)methanone
CAS 2804137-18-4C11H8ClF5N2O
(2-Bromo-5-chloropyridin-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C10H10BrClN2O, CAS 2668247-31-0
(2-Bromo-5-chloropyridin-3-yl)(pyrrolidin-1-yl)methanone
CAS 2668247-31-0C10H10BrClN2O
Pyrrolidin-1-yl(5-vinylpyridin-3-yl)methanone chemical structure, C12H14N2O, CAS 2819317-10-5
Pyrrolidin-1-yl(5-vinylpyridin-3-yl)methanone
CAS 2819317-10-5C12H14N2O