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Murcko scaffold

Ring system with 3 rings and 18 atoms

72 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
72
With full pages
8
Scaffold SMILES

O=S(=O)(c1ccccc1)c1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 72 chemicals

3-Benzenesulfonyl-5-chloroindole-2-carboxamide chemical structure, C15H11ClN2O3S, CAS 148472-83-7
3-Benzenesulfonyl-5-chloroindole-2-carboxamide
CAS 148472-83-7C15H11ClN2O3S
1H-Indole-2-carboxylic acid, 3-((2-aminophenyl)sulfonyl)-, ethyl ester chemical structure, C17H16N2O4S, CAS 206256-31-7
1H-Indole-2-carboxylic acid, 3-((2-aminophenyl)sulfonyl)-, ethyl ester
CAS 206256-31-7C17H16N2O4S
1H-Indole-2-carboxylic acid, 3-((2-amino-5-chlorophenyl)sulfonyl)-, ethyl ester chemical structure, C17H15ClN2O4S, CAS 206256-17-9
1H-Indole-2-carboxylic acid, 3-((2-amino-5-chlorophenyl)sulfonyl)-, ethyl ester
CAS 206256-17-9C17H15ClN2O4S
1H-Indole-2-carboxylic acid, 3-((2-aminophenyl)sulfonyl)-5-chloro-, ethyl ester chemical structure, C17H15ClN2O4S, CAS 206256-32-8
1H-Indole-2-carboxylic acid, 3-((2-aminophenyl)sulfonyl)-5-chloro-, ethyl ester
CAS 206256-32-8C17H15ClN2O4S
Ethyl 3-[(2-amino-5-chlorophenyl)sulfonyl]-5-chloro-1H-indole-2-carboxylate chemical structure, C17H14Cl2N2O4S, CAS 206256-33-9
Ethyl 3-[(2-amino-5-chlorophenyl)sulfonyl]-5-chloro-1H-indole-2-carboxylate
CAS 206256-33-9C17H14Cl2N2O4S
1H-Indole-2-carboxylic acid, 3-(phenylsulfonyl)-, ethyl ester chemical structure, C17H15NO4S, CAS 158561-81-0
1H-Indole-2-carboxylic acid, 3-(phenylsulfonyl)-, ethyl ester
CAS 158561-81-0C17H15NO4S
1H-Indole-2-carboxamide, 3-(phenylsulfonyl)- chemical structure, C15H12N2O3S, CAS 540740-84-9
1H-Indole-2-carboxamide, 3-(phenylsulfonyl)-
CAS 540740-84-9C15H12N2O3S
1H-Indole-2-carboxamide, 3-[(2-amino-5-chlorophenyl)sulfonyl]- chemical structure, C15H12ClN3O3S, CAS 540740-85-0
1H-Indole-2-carboxamide, 3-[(2-amino-5-chlorophenyl)sulfonyl]-
CAS 540740-85-0C15H12ClN3O3S
1H-Indole-2-carboxamide, 5-chloro-3-[(2-methylphenyl)sulfonyl]- chemical structure, C16H13ClN2O3S, CAS 540740-86-1
1H-Indole-2-carboxamide, 5-chloro-3-[(2-methylphenyl)sulfonyl]-
CAS 540740-86-1C16H13ClN2O3S
1H-Indole-2-carboxamide, 5-chloro-3-[(3-methylphenyl)sulfonyl]- chemical structure, C16H13ClN2O3S, CAS 540740-87-2
1H-Indole-2-carboxamide, 5-chloro-3-[(3-methylphenyl)sulfonyl]-
CAS 540740-87-2C16H13ClN2O3S
1H-Indole-2-carboxamide, 5-chloro-3-[(4-methylphenyl)sulfonyl]- chemical structure, C16H13ClN2O3S, CAS 540740-88-3
1H-Indole-2-carboxamide, 5-chloro-3-[(4-methylphenyl)sulfonyl]-
CAS 540740-88-3C16H13ClN2O3S
1H-Indole-2-carboxamide, 5-chloro-3-[(4-fluorophenyl)sulfonyl]- chemical structure, C15H10ClFN2O3S, CAS 540740-89-4
1H-Indole-2-carboxamide, 5-chloro-3-[(4-fluorophenyl)sulfonyl]-
CAS 540740-89-4C15H10ClFN2O3S
1H-Indole-2-carboxamide, 5-chloro-3-[[4-(1-methylethyl)phenyl]sulfonyl]- chemical structure, C18H17ClN2O3S, CAS 540740-90-7
1H-Indole-2-carboxamide, 5-chloro-3-[[4-(1-methylethyl)phenyl]sulfonyl]-
CAS 540740-90-7C18H17ClN2O3S
1H-Indole-2-carboxamide, 5-chloro-3-[(2,4-dimethylphenyl)sulfonyl]- chemical structure, C17H15ClN2O3S, CAS 540740-92-9
1H-Indole-2-carboxamide, 5-chloro-3-[(2,4-dimethylphenyl)sulfonyl]-
CAS 540740-92-9C17H15ClN2O3S
5-Chloro-3-(3,5-dimethylbenzenesulfonyl)-1H-indole-2-carboxamide chemical structure, C17H15ClN2O3S, CAS 473257-93-1
5-Chloro-3-(3,5-dimethylbenzenesulfonyl)-1H-indole-2-carboxamide
CAS 473257-93-1C17H15ClN2O3S
1H-Indole-2-carboxamide, 5-chloro-3-[(2,6-dichlorophenyl)sulfonyl]- chemical structure, C15H9Cl3N2O3S, CAS 540740-93-0
1H-Indole-2-carboxamide, 5-chloro-3-[(2,6-dichlorophenyl)sulfonyl]-
CAS 540740-93-0C15H9Cl3N2O3S
1H-Indole-2-carboxamide, 5-bromo-3-[(3,5-dimethylphenyl)sulfonyl]- chemical structure, C17H15BrN2O3S, CAS 540740-95-2
1H-Indole-2-carboxamide, 5-bromo-3-[(3,5-dimethylphenyl)sulfonyl]-
CAS 540740-95-2C17H15BrN2O3S
N-(2-Amino-2-oxo-ethyl)-5-chloro-3-(3,5-dimethylphenyl)sulfonyl-1H-indole-2-carboxamide chemical structure, C19H18ClN3O4S, CAS 473257-56-6
N-(2-Amino-2-oxo-ethyl)-5-chloro-3-(3,5-dimethylphenyl)sulfonyl-1H-indole-2-carboxamide
CAS 473257-56-6C19H18ClN3O4S
1-(Methoxymethyl)-3-(4-methylbenzenesulfonyl)-5-(prop-2-en-1-yloxy)-1H-indole chemical structure, C20H21NO4S, CAS 186263-45-6
1-(Methoxymethyl)-3-(4-methylbenzenesulfonyl)-5-(prop-2-en-1-yloxy)-1H-indole
CAS 186263-45-6C20H21NO4S
5-Methoxy-3-(4-methylphenyl)sulfonyl-1H-indole chemical structure, C16H15NO3S, CAS 329905-59-1
5-Methoxy-3-(4-methylphenyl)sulfonyl-1H-indole
CAS 329905-59-1C16H15NO3S
1H-Indole-1-acetic acid, 5-chloro-3-[(4-chlorophenyl)sulfonyl]-2-methyl- chemical structure, C17H13Cl2NO4S, CAS 646514-32-1
1H-Indole-1-acetic acid, 5-chloro-3-[(4-chlorophenyl)sulfonyl]-2-methyl-
CAS 646514-32-1C17H13Cl2NO4S
2-[3-(3-Chlorophenyl)sulfonyl-2,5-dimethylindol-1-yl]acetic acid chemical structure, C18H16ClNO4S, CAS 646514-95-6
2-[3-(3-Chlorophenyl)sulfonyl-2,5-dimethylindol-1-yl]acetic acid
CAS 646514-95-6C18H16ClNO4S
1H-Indole-1-acetic acid, 7-chloro-3-[(4-chlorophenyl)sulfonyl]-2-methyl- chemical structure, C17H13Cl2NO4S, CAS 646514-42-3
1H-Indole-1-acetic acid, 7-chloro-3-[(4-chlorophenyl)sulfonyl]-2-methyl-
CAS 646514-42-3C17H13Cl2NO4S
2-[3-(3-Methoxyphenyl)sulfonyl-2,5-dimethylindol-1-yl]acetic acid chemical structure, C19H19NO5S, CAS 646514-88-7
2-[3-(3-Methoxyphenyl)sulfonyl-2,5-dimethylindol-1-yl]acetic acid
CAS 646514-88-7C19H19NO5S