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Murcko scaffold

Ring system with 2 rings and 15 atoms

24 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
24
With full pages
12
Scaffold SMILES

O=c1ccn(S(=O)(=O)c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(S(=O)(=O)c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

4-(2-Hydroxyethyl)-2,5-dimethyl-1-[(4-nitrophenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H15N3O6S, CAS 866018-82-8
4-(2-Hydroxyethyl)-2,5-dimethyl-1-[(4-nitrophenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one
CAS 866018-82-8C13H15N3O6S
4-(2-Hydroxyethyl)-1-[(4-iodophenyl)sulfonyl]-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H15IN2O4S, CAS 866039-54-5
4-(2-Hydroxyethyl)-1-[(4-iodophenyl)sulfonyl]-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866039-54-5C13H15IN2O4S
1-[(4-Chlorophenyl)sulfonyl]-4-(2-hydroxyethyl)-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H15ClN2O4S, CAS 866039-56-7
1-[(4-Chlorophenyl)sulfonyl]-4-(2-hydroxyethyl)-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866039-56-7C13H15ClN2O4S
4-(2-Hydroxyethyl)-2,5-dimethyl-1-[(4-methylphenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one chemical structure, C14H18N2O4S, CAS 866039-57-8
4-(2-Hydroxyethyl)-2,5-dimethyl-1-[(4-methylphenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one
CAS 866039-57-8C14H18N2O4S
4-(2-Hydroxyethyl)-5-methyl-1-[(4-nitrophenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one chemical structure, C12H13N3O6S, CAS 866039-59-0
4-(2-Hydroxyethyl)-5-methyl-1-[(4-nitrophenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one
CAS 866039-59-0C12H13N3O6S
1-[(2,5-Dichlorophenyl)sulfonyl]-4-(2-hydroxyethyl)-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H14Cl2N2O4S, CAS 866039-60-3
1-[(2,5-Dichlorophenyl)sulfonyl]-4-(2-hydroxyethyl)-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866039-60-3C13H14Cl2N2O4S
4-(2-Hydroxyethyl)-1-(mesitylsulfonyl)-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C16H22N2O4S, CAS 866039-65-8
4-(2-Hydroxyethyl)-1-(mesitylsulfonyl)-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866039-65-8C16H22N2O4S
4-(2-Hydroxyethyl)-2,5-dimethyl-1-[(2-nitrophenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H15N3O6S, CAS 866039-86-3
4-(2-Hydroxyethyl)-2,5-dimethyl-1-[(2-nitrophenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one
CAS 866039-86-3C13H15N3O6S
1-[(4-Fluorophenyl)sulfonyl]-4-(2-hydroxyethyl)-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H15FN2O4S, CAS 866039-87-4
1-[(4-Fluorophenyl)sulfonyl]-4-(2-hydroxyethyl)-2,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866039-87-4C13H15FN2O4S
2-(tert-Butyl)-4-(2-hydroxyethyl)-1-[(4-methoxyphenyl)sulfonyl]-5-methyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C17H24N2O5S, CAS 866040-24-6
2-(tert-Butyl)-4-(2-hydroxyethyl)-1-[(4-methoxyphenyl)sulfonyl]-5-methyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866040-24-6C17H24N2O5S
4-(2-Hydroxyethyl)-1-[(4-methoxyphenyl)sulfonyl]-5-methyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H16N2O5S, CAS 866040-29-1
4-(2-Hydroxyethyl)-1-[(4-methoxyphenyl)sulfonyl]-5-methyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866040-29-1C13H16N2O5S
1-[(4-Fluorophenyl)sulfonyl]-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C12H13FN2O4S, CAS 866040-30-4
1-[(4-Fluorophenyl)sulfonyl]-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866040-30-4C12H13FN2O4S
4-(2-Hydroxyethyl)-5-methyl-1-{[3-(trifluoromethyl)phenyl]sulfonyl}-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H13F3N2O4S, CAS 866050-06-8
4-(2-Hydroxyethyl)-5-methyl-1-{[3-(trifluoromethyl)phenyl]sulfonyl}-1,2-dihydro-3H-pyrazol-3-one
CAS 866050-06-8C13H13F3N2O4S
1-[(2,4-Dichlorophenyl)sulfonyl]-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C12H12Cl2N2O4S, CAS 866050-07-9
1-[(2,4-Dichlorophenyl)sulfonyl]-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one
CAS 866050-07-9C12H12Cl2N2O4S
4-(2-Hydroxyethyl)-5-methyl-1-(phenylsulfonyl)-1,2-dihydro-3H-pyrazol-3-one chemical structure, C12H14N2O4S, CAS 866050-08-0
4-(2-Hydroxyethyl)-5-methyl-1-(phenylsulfonyl)-1,2-dihydro-3H-pyrazol-3-one
CAS 866050-08-0C12H14N2O4S
4-(2-Hydroxyethyl)-1-[(4-iodophenyl)sulfonyl]-5-methyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C12H13IN2O4S, CAS 860611-73-0
4-(2-Hydroxyethyl)-1-[(4-iodophenyl)sulfonyl]-5-methyl-1,2-dihydro-3H-pyrazol-3-one
CAS 860611-73-0C12H13IN2O4S
4-(2-Hydroxyethyl)-5-methyl-1-[(2-nitrophenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one chemical structure, C12H13N3O6S, CAS 860611-74-1
4-(2-Hydroxyethyl)-5-methyl-1-[(2-nitrophenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one
CAS 860611-74-1C12H13N3O6S
4-(2-Hydroxyethyl)-5-methyl-1-[(4-methylphenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H16N2O4S, CAS 860611-79-6
4-(2-Hydroxyethyl)-5-methyl-1-[(4-methylphenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one
CAS 860611-79-6C13H16N2O4S
4-(2-Hydroxyethyl)-1-[(4-methoxy-2-nitrophenyl)sulfonyl]-5-methyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H15N3O7S, CAS 861207-36-5
4-(2-Hydroxyethyl)-1-[(4-methoxy-2-nitrophenyl)sulfonyl]-5-methyl-1,2-dihydro-3H-pyrazol-3-one
CAS 861207-36-5C13H15N3O7S
1-[(2,4-Dichloro-5-methylphenyl)sulfonyl]-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one chemical structure, C13H14Cl2N2O4S, CAS 861207-41-2
1-[(2,4-Dichloro-5-methylphenyl)sulfonyl]-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one
CAS 861207-41-2C13H14Cl2N2O4S
4-(2-Hydroxyethyl)-5-methyl-1-[(2,3,4,5,6-pentamethylphenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one chemical structure, C17H24N2O4S, CAS 861207-39-8
4-(2-Hydroxyethyl)-5-methyl-1-[(2,3,4,5,6-pentamethylphenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one
CAS 861207-39-8C17H24N2O4S
5-Amino-1-(4-methylphenylsulfonyl)-4-pyrazolin-3-one chemical structure, C10H11N3O3S, CAS 240117-38-8
5-Amino-1-(4-methylphenylsulfonyl)-4-pyrazolin-3-one
CAS 240117-38-8C10H11N3O3S
5-Amino-1-(4-methoxybenzenesulfonyl)-1H-pyrazol-3-ol chemical structure, C10H11N3O4S, CAS 240117-39-9
5-Amino-1-(4-methoxybenzenesulfonyl)-1H-pyrazol-3-ol
CAS 240117-39-9C10H11N3O4S
5-Amino-1-((3-chlorophenyl)sulfonyl)-1H-pyrazol-3-ol chemical structure, C9H8ClN3O3S, CAS 2034469-90-2
5-Amino-1-((3-chlorophenyl)sulfonyl)-1H-pyrazol-3-ol
CAS 2034469-90-2C9H8ClN3O3S