Murcko scaffold
Cyclopropylbenzene scaffold
19,216 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 19,216
- With full pages
- 778
Scaffold SMILES
c1ccc(C2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,393 to 1,440 of 19,216 chemicals
1-(3,5-Dimethylphenyl)cyclopropan-1-amine
CAS 1154178-50-3C11H15N
1-(2-(3,4-Dimethylphenyl)cyclopropyl)ethanamine
CAS 1218157-43-7C13H19N
2-(4-Ethylphenyl)cyclopropane-1-carboxylic acid
CAS 1048919-59-0C12H14O2
2-(2,4,6-Trimethylphenyl)cyclopropane-1-carboxylic acid
CAS 1157137-78-4C13H16O2
2-(2,6-Difluorophenyl)cyclopropane-1-carboxylic acid
CAS 1157561-48-2C10H8F2O2
2-(2,4-Dimethylphenyl)cyclopropane-1-carboxylic acid
CAS 1157561-78-8C12H14O2
2-(5-BroMo-2-fluorophenyl)cyclopropanecarboxylic acid
CAS 1157561-84-6C10H8BrFO2
2-(3-BroMo-4-fluorophenyl)cyclopropanecarboxylic acid
CAS 1157138-03-8C10H8BrFO2
![2-[2-(Trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid chemical structure, C11H9F3O3, CAS 1157562-08-7](/s/URRRSJNYUQVDCI-UHFFFAOYSA-N.svg)
2-[2-(Trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid
CAS 1157562-08-7C11H9F3O3
2-(4-((Trifluoromethyl)thio)phenyl)cyclopropane-1-carboxylic acid
CAS 1157562-15-6C11H9F3O2S
2-(3-Cyanophenyl)cyclopropane-1-carboxylic acid
CAS 352616-04-7C11H9NO2
2-(2,4-Difluorophenyl)cyclopropane-1-carboxylic acid
CAS 1157642-22-2C10H8F2O2
2-(2-Methylphenyl)cyclopropane-1-carboxylic acid
CAS 1048919-52-3C11H12O2
2-(4-Cyanophenyl)cyclopropane-1-carboxylic acid
CAS 1157138-40-3C11H9NO2
2-(2,4-Dimethoxyphenyl)cyclopropane-1-carboxylic acid
CAS 1157642-31-3C12H14O4
![2-[4-(Difluoromethoxy)phenyl]cyclopropane-1-carboxylic acid chemical structure, C11H10F2O3, CAS 1157554-33-0](/s/XRVPPNOXFATEAL-UHFFFAOYSA-N.svg)
2-[4-(Difluoromethoxy)phenyl]cyclopropane-1-carboxylic acid
CAS 1157554-33-0C11H10F2O3
2-(2-Ethoxyphenyl)cyclopropanecarboxylic acid
CAS 1017553-76-2C12H14O3
2-(2-Chloro-6-fluorophenyl)cyclopropanecarboxylic acid
CAS 1157642-59-5C10H8ClFO2
2-(2,3-Dimethoxyphenyl)cyclopropane-1-carboxylic acid
CAS 1157554-51-2C12H14O4
2-(2,4-Dichlorophenyl)cyclopropane-1-carboxylic acid
CAS 1157554-61-4C10H8Cl2O2
2-(4-(Propan-2-yl)phenyl)cyclopropane-1-carboxylic acid
CAS 1048919-66-9C13H16O2
2-(4-Ethoxyphenyl)cyclopropane-1-carboxylic acid
CAS 1157642-68-6C12H14O3
2-(2-Bromophenyl)cyclopropanecarboxylic acid
CAS 767359-25-1C10H9BrO2
2-(2,5-Dimethoxyphenyl)cyclopropane-1-carboxylic acid
CAS 1157138-78-7C12H14O4
- 2-(5-Bromo-2-methoxyphenyl)cyclopropane-1-carboxylic acid1157139-02-0C11H11BrO3
- 2-(4-Bromo-2-fluorophenyl)cyclopropane-1-carboxylic acid1056010-27-5C10H8BrFO2
- 2-(2,3-Dichlorophenyl)cyclopropanecarboxylic acid1157698-55-9C10H8Cl2O2
- 2-(2,6-Dichlorophenyl)cyclopropane-1-carboxylic acid1157698-73-1C10H8Cl2O2
- 2-[2-(Difluoromethoxy)phenyl]cyclopropane-1-carboxylic acid1157139-29-1C11H10F2O3
- 2-(2,4,6-Trimethoxyphenyl)cyclopropan-1-amine1157698-79-7C12H17NO3
- 2-(2,5-Difluorophenyl)cyclopropan-1-amine1157692-93-7C9H9F2N
- 2-(2,3-Dichlorophenyl)cyclopropan-1-amine1157139-40-6C9H9Cl2N
- 2-(2,6-Dichlorophenyl)cyclopropan-1-amine1157139-48-4C9H9Cl2N
- 2-[2-(Difluoromethoxy)phenyl]cyclopropan-1-amine1157693-02-1C10H11F2NO
- 2-(4-Ethylphenyl)cyclopropan-1-amine1157693-09-8C11H15N
- 2-Mesitylcyclopropan-1-amine1001319-97-6C12H17N
- 2-(2,4-Dimethylphenyl)cyclopropan-1-amine1157554-76-1C11H15N
- 2-(4-(tert-Butyl)phenyl)cyclopropan-1-amine1157693-23-6C13H19N
- 2-(5-Bromo-2-fluorophenyl)cyclopropan-1-amine1157554-83-0C9H9BrFN
- 2-(3-Bromo-4-fluorophenyl)cyclopropan-1-amine1157555-06-0C9H9BrFN
- 2-[2-(Trifluoromethoxy)phenyl]cyclopropan-1-amine1157555-15-1C10H10F3NO
- 2-{4-[(Trifluoromethyl)sulfanyl]phenyl}cyclopropan-1-amine1157139-99-5C10H10F3NS
- 3-(2-Aminocyclopropyl)benzonitrile1157555-25-3C10H10N2
- 2-(2,4-Difluorophenyl)cyclopropan-1-amine1001318-18-8C9H9F2N
- 2-[4-(Trifluoromethyl)phenyl]cyclopropan-1-amine2248-47-7C10H10F3N
- 4-(2-Aminocyclopropyl)benzonitrile1157693-55-4C10H10N2
- 2-(2,4-Dimethoxyphenyl)cyclopropan-1-amine1157140-36-7C11H15NO2
- 2-(2-Nitrophenyl)cyclopropan-1-amine1157140-41-4C9H10N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(C2CO2)cc1108 chemicals
c1ccc(C2CC2)nc182 chemicals
c1cnc(C2CC2)nc163 chemicals
c1cncc(C2CC2)c150 chemicals
c1ccc(C2N=N2)cc135 chemicals
c1cc(C2CC2)ncn126 chemicals
c1cc(C2CC2)ccn124 chemicals
C1CNCC(C2CC2)C115 chemicals
C1CC(C2CC2)CCN115 chemicals
C1CCC(C2CC2)CC115 chemicals
C1CC(C2CC2)CCO111 chemicals![Scaffold O=c1ccnc(C2CC2)[nH]1](/scaffold/HADXIKCWXJVQEO-UHFFFAOYSA-N/structure.svg)
O=c1ccnc(C2CC2)[nH]111 chemicals