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Murcko scaffold

2-Phenylisothiazol-3(2H)-one scaffold

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
27
With full pages
7
Scaffold SMILES

O=c1ccsn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenylisothiazol-3(2H)-one page
Murcko scaffold O=c1ccsn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

RefChem:925056 chemical structure, C9H5ClFNOS, CAS 147104-27-6
RefChem:925056
CAS 147104-27-6C9H5ClFNOS
2-(3-Chloro-2-fluorophenyl)isothiazol-3(2H)-one chemical structure, C9H5ClFNOS, CAS 220862-89-5
2-(3-Chloro-2-fluorophenyl)isothiazol-3(2H)-one
CAS 220862-89-5C9H5ClFNOS
5-Chloro-2-(4-chlorophenyl)-4-methyl-3(2H)-isothiazolone chemical structure, C10H7Cl2NOS, CAS 66160-25-6
5-Chloro-2-(4-chlorophenyl)-4-methyl-3(2H)-isothiazolone
CAS 66160-25-6C10H7Cl2NOS
Ethyl 4-(3-oxoisothiazol-2(3H)-yl)benzoate chemical structure, C12H11NO3S, CAS 26530-26-7
Ethyl 4-(3-oxoisothiazol-2(3H)-yl)benzoate
CAS 26530-26-7C12H11NO3S
2-[3-(Trifluoromethyl)phenyl]-4-isothiazoline-3-one chemical structure, C10H6F3NOS, CAS 220862-87-3
2-[3-(Trifluoromethyl)phenyl]-4-isothiazoline-3-one
CAS 220862-87-3C10H6F3NOS
3(2H)-Isothiazolone, 2-[4-(trifluoromethoxy)phenyl]- chemical structure, C10H6F3NO2S, CAS 164348-31-6
3(2H)-Isothiazolone, 2-[4-(trifluoromethoxy)phenyl]-
CAS 164348-31-6C10H6F3NO2S
2-Phenylisothiazol-3(2H)-one chemical structure, C9H7NOS, CAS 21277-98-5
2-Phenylisothiazol-3(2H)-one
CAS 21277-98-5C9H7NOS
5-Chloro-2-(4-(dimethylamino)phenyl)isothiazol-3(2H)-one chemical structure, C11H11ClN2OS, CAS 748777-53-9
5-Chloro-2-(4-(dimethylamino)phenyl)isothiazol-3(2H)-one
CAS 748777-53-9C11H11ClN2OS
5-Chloro-2-(4-nitrophenyl)-3(2H)-isothiazolone chemical structure, C9H5ClN2O3S, CAS 748777-47-1
5-Chloro-2-(4-nitrophenyl)-3(2H)-isothiazolone
CAS 748777-47-1C9H5ClN2O3S
Ethyl 4-(5-chloro-3-oxo-2(3H)-isothiazolyl)benzoate chemical structure, C12H10ClNO3S, CAS 748777-48-2
Ethyl 4-(5-chloro-3-oxo-2(3H)-isothiazolyl)benzoate
CAS 748777-48-2C12H10ClNO3S
2-(4-Chlorophenyl)-1,2-thiazol-3(2H)-one chemical structure, C9H6ClNOS, CAS 33319-86-7
2-(4-Chlorophenyl)-1,2-thiazol-3(2H)-one
CAS 33319-86-7C9H6ClNOS
2-(3,4-Dichlorophenyl)-4-methyl-3-isothiazolone chemical structure, C10H7Cl2NOS, CAS 26172-56-5
2-(3,4-Dichlorophenyl)-4-methyl-3-isothiazolone
CAS 26172-56-5C10H7Cl2NOS
2-(3-Chlorophenyl)-2,3-dihydro-1,2-thiazol-3-one chemical structure, C9H6ClNOS, CAS 33319-85-6
2-(3-Chlorophenyl)-2,3-dihydro-1,2-thiazol-3-one
CAS 33319-85-6C9H6ClNOS
2-(4-Trifluoromethoxyphenyl)-5-chloro-4-isothiazolin-3-on chemical structure, C10H5ClF3NO2S, CAS 164348-32-7
2-(4-Trifluoromethoxyphenyl)-5-chloro-4-isothiazolin-3-on
CAS 164348-32-7C10H5ClF3NO2S
4,5-Dichloro-2-[4-(trifluoromethoxy)phenyl]-1,2-thiazol-3(2H)-one chemical structure, C10H4Cl2F3NO2S, CAS 164348-33-8
4,5-Dichloro-2-[4-(trifluoromethoxy)phenyl]-1,2-thiazol-3(2H)-one
CAS 164348-33-8C10H4Cl2F3NO2S
5-Chloro-4-methyl-2-phenylisothiazol-3(2H)-one chemical structure, C10H8ClNOS, CAS 54415-07-5
5-Chloro-4-methyl-2-phenylisothiazol-3(2H)-one
CAS 54415-07-5C10H8ClNOS
4,5-Dichloro-2-(4-chlorophenyl)-1,2-thiazol-3(2H)-one chemical structure, C9H4Cl3NOS, CAS 26858-22-0
4,5-Dichloro-2-(4-chlorophenyl)-1,2-thiazol-3(2H)-one
CAS 26858-22-0C9H4Cl3NOS
2-(2,4-Difluorophenyl)-2,3-dihydro-1,2-thiazol-3-one chemical structure, C9H5F2NOS, CAS 951900-41-7
2-(2,4-Difluorophenyl)-2,3-dihydro-1,2-thiazol-3-one
CAS 951900-41-7C9H5F2NOS
5-Chloro-2-(4-fluorophenyl)-4-methylisothiazol-3(2H)-one chemical structure, C10H7ClFNOS, CAS 66160-26-7
5-Chloro-2-(4-fluorophenyl)-4-methylisothiazol-3(2H)-one
CAS 66160-26-7C10H7ClFNOS
5-Chloro-2-(3-fluorophenyl)isothiazol-3(2H)-one chemical structure, C9H5ClFNOS, CAS 1213258-30-0
5-Chloro-2-(3-fluorophenyl)isothiazol-3(2H)-one
CAS 1213258-30-0C9H5ClFNOS
5-Chloro-2-(3-chlorophenyl)isothiazol-3(2H)-one chemical structure, C9H5Cl2NOS, CAS 1213258-31-1
5-Chloro-2-(3-chlorophenyl)isothiazol-3(2H)-one
CAS 1213258-31-1C9H5Cl2NOS
Methyl 4-(3-oxoisothiazol-2(3H)-yl)benzoate chemical structure, C11H9NO3S, CAS 1309368-73-7
Methyl 4-(3-oxoisothiazol-2(3H)-yl)benzoate
CAS 1309368-73-7C11H9NO3S
4,5-Dichloro-2-(2,6-dimethylphenyl)-1,2-thiazol-3(2H)-one chemical structure, C11H9Cl2NOS, CAS 142060-13-7
4,5-Dichloro-2-(2,6-dimethylphenyl)-1,2-thiazol-3(2H)-one
CAS 142060-13-7C11H9Cl2NOS
2-(4-Propanoylphenyl)-1,2-thiazol-3(2H)-one chemical structure, C12H11NO2S, CAS 870476-67-8
2-(4-Propanoylphenyl)-1,2-thiazol-3(2H)-one
CAS 870476-67-8C12H11NO2S