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Murcko scaffold

4-Benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one scaffold

48 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
48
With full pages
6
Scaffold SMILES

O=C1COc2ccccc2N1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one page
Murcko scaffold O=C1COc2ccccc2N1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

4-Benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one chemical structure, C15H13NO2, CAS 63208-65-1
4-Benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one
CAS 63208-65-1C15H13NO2
4-[(2-Chlorophenyl)methyl]-2-methyl-1,4-benzoxazin-3-one chemical structure, C16H14ClNO2, CAS 626225-81-8
4-[(2-Chlorophenyl)methyl]-2-methyl-1,4-benzoxazin-3-one
CAS 626225-81-8C16H14ClNO2
4-(2-Chloro-6-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one chemical structure, C15H11ClFNO2, CAS 626226-19-5
4-(2-Chloro-6-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one
CAS 626226-19-5C15H11ClFNO2
4-[(3-Oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)methyl]benzoic acid chemical structure, C16H13NO4, CAS 857492-98-9
4-[(3-Oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)methyl]benzoic acid
CAS 857492-98-9C16H13NO4
4-(4-Carboxybenzyl)-6-chloro-2H-1,4-benzoxazin-3(4H)-one chemical structure, C16H12ClNO4, CAS 874605-63-7
4-(4-Carboxybenzyl)-6-chloro-2H-1,4-benzoxazin-3(4H)-one
CAS 874605-63-7C16H12ClNO4
4-(4-Fluorobenzyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one chemical structure, C16H14FNO2, CAS 626225-57-8
4-(4-Fluorobenzyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one
CAS 626225-57-8C16H14FNO2
4-(3-Methoxybenzyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one chemical structure, C17H17NO3, CAS 866157-85-9
4-(3-Methoxybenzyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one
CAS 866157-85-9C17H17NO3
4-(2,4-Dimethylbenzyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one chemical structure, C18H19NO2, CAS 866157-84-8
4-(2,4-Dimethylbenzyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one
CAS 866157-84-8C18H19NO2
3-[(6-Methyl-3-oxo-1,4-benzoxazin-4-yl)methyl]-N-pentylbenzamide chemical structure, C22H26N2O3, CAS 6042-52-0
3-[(6-Methyl-3-oxo-1,4-benzoxazin-4-yl)methyl]-N-pentylbenzamide
CAS 6042-52-0C22H26N2O3
4-Benzyl-6-chloro-2H-1,4-benzoxazin-3(4H)-one chemical structure, C15H12ClNO2, CAS 915885-16-4
4-Benzyl-6-chloro-2H-1,4-benzoxazin-3(4H)-one
CAS 915885-16-4C15H12ClNO2
6-Chloro-4-(2-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one chemical structure, C15H11ClFNO2, CAS 892682-32-5
6-Chloro-4-(2-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one
CAS 892682-32-5C15H11ClFNO2
6-Chloro-4-(2-chlorobenzyl)-2H-1,4-benzoxazin-3(4H)-one chemical structure, C15H11Cl2NO2, CAS 892682-27-8
6-Chloro-4-(2-chlorobenzyl)-2H-1,4-benzoxazin-3(4H)-one
CAS 892682-27-8C15H11Cl2NO2
6-Chloro-4-(2-chloro-6-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one chemical structure, C15H10Cl2FNO2, CAS 892682-37-0
6-Chloro-4-(2-chloro-6-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one
CAS 892682-37-0C15H10Cl2FNO2
4-((6-Chloro-2,3-dihydro-2-methyl-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoic acid chemical structure, C17H14ClNO4, CAS 900706-45-8
4-((6-Chloro-2,3-dihydro-2-methyl-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoic acid
CAS 900706-45-8C17H14ClNO4
4-((2,3-Dihydro-2-methyl-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoic acid chemical structure, C17H15NO4, CAS 900706-47-0
4-((2,3-Dihydro-2-methyl-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoic acid
CAS 900706-47-0C17H15NO4
4-(4-Bromobenzyl)-2H-1,4-benzoxazin-3(4H)-one chemical structure, C15H12BrNO2, CAS 915872-77-4
4-(4-Bromobenzyl)-2H-1,4-benzoxazin-3(4H)-one
CAS 915872-77-4C15H12BrNO2
7-Amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one chemical structure, C15H14N2O2, CAS 917748-98-2
7-Amino-4-benzyl-2H-benzo[b][1,4]oxazin-3(4H)-one
CAS 917748-98-2C15H14N2O2
4-Benzyl-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid chemical structure, C17H15NO4, CAS 165114-64-7
4-Benzyl-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid
CAS 165114-64-7C17H15NO4
4-((2,3-Dihydro-2,6-dimethyl-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoic acid chemical structure, C18H17NO4, CAS 943110-47-2
4-((2,3-Dihydro-2,6-dimethyl-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoic acid
CAS 943110-47-2C18H17NO4
4-Benzyl-6-methyl-2H-1,4-benzoxazin-3(4H)-one chemical structure, C16H15NO2, CAS 648450-64-0
4-Benzyl-6-methyl-2H-1,4-benzoxazin-3(4H)-one
CAS 648450-64-0C16H15NO2
6-Amino-4-(4-fluorobenzyl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one chemical structure, C16H15FN2O2, CAS 1017144-66-9
6-Amino-4-(4-fluorobenzyl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one
CAS 1017144-66-9C16H15FN2O2
6-Amino-4-[(4-chlorophenyl)methyl]-2-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one chemical structure, C16H15ClN2O2, CAS 1017330-63-0
6-Amino-4-[(4-chlorophenyl)methyl]-2-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one
CAS 1017330-63-0C16H15ClN2O2
6-Amino-4-benzyl-2H-1,4-benzoxazin-3(4H)-one chemical structure, C15H14N2O2, CAS 1007671-23-9
6-Amino-4-benzyl-2H-1,4-benzoxazin-3(4H)-one
CAS 1007671-23-9C15H14N2O2
8-Amino-4-(4-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one chemical structure, C15H13FN2O2, CAS 1018570-68-7
8-Amino-4-(4-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one
CAS 1018570-68-7C15H13FN2O2