CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 12 atoms

21 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
21
With full pages
6
Scaffold SMILES

c1ccc(Nc2ncns2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ncns2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

3-Methylthio-5-phenylamino-1,2,4-thiadiazole chemical structure, C9H9N3S2, CAS 35746-47-5
3-Methylthio-5-phenylamino-1,2,4-thiadiazole
CAS 35746-47-5C9H9N3S2
1-{5-[(3,4-Dimethoxyphenyl)amino]-1,2,4-thiadiazol-3-yl}propan-2-one chemical structure, C13H15N3O3S, CAS 521329-08-8
1-{5-[(3,4-Dimethoxyphenyl)amino]-1,2,4-thiadiazol-3-yl}propan-2-one
CAS 521329-08-8C13H15N3O3S
1-{5-[(4-Methoxyphenyl)amino]-1,2,4-thiadiazol-3-yl}propan-2-one chemical structure, C12H13N3O2S, CAS 443110-87-0
1-{5-[(4-Methoxyphenyl)amino]-1,2,4-thiadiazol-3-yl}propan-2-one
CAS 443110-87-0C12H13N3O2S
1-{5-[(4-Methylphenyl)amino]-1,2,4-thiadiazol-3-yl}propan-2-one chemical structure, C12H13N3OS, CAS 443111-46-4
1-{5-[(4-Methylphenyl)amino]-1,2,4-thiadiazol-3-yl}propan-2-one
CAS 443111-46-4C12H13N3OS
1-(5-Anilino-1,2,4-thiadiazol-3-yl)propan-2-one chemical structure, C11H11N3OS, CAS 64822-00-0
1-(5-Anilino-1,2,4-thiadiazol-3-yl)propan-2-one
CAS 64822-00-0C11H11N3OS
3-Amino-5-phenylamino-1,2,4-thiadiazole chemical structure, C8H8N4S, CAS 60093-15-4
3-Amino-5-phenylamino-1,2,4-thiadiazole
CAS 60093-15-4C8H8N4S
5-Anilino-3-methoxy-1,2,4-thiadiazole chemical structure, C9H9N3OS, CAS 90564-94-6
5-Anilino-3-methoxy-1,2,4-thiadiazole
CAS 90564-94-6C9H9N3OS
1-[5-(4-Fluoroanilino)-1,2,4-thiadiazol-3-yl]propan-2-one chemical structure, C11H10FN3OS, CAS 443110-99-4
1-[5-(4-Fluoroanilino)-1,2,4-thiadiazol-3-yl]propan-2-one
CAS 443110-99-4C11H10FN3OS
N-Phenyl-3-[(prop-2-en-1-yl)sulfanyl]-1,2,4-thiadiazol-5-amine chemical structure, C11H11N3S2, CAS 35746-59-9
N-Phenyl-3-[(prop-2-en-1-yl)sulfanyl]-1,2,4-thiadiazol-5-amine
CAS 35746-59-9C11H11N3S2
3-Methyl-N-phenyl-1,2,4-thiadiazol-5-amine chemical structure, C9H9N3S, CAS 17467-18-4
3-Methyl-N-phenyl-1,2,4-thiadiazol-5-amine
CAS 17467-18-4C9H9N3S
(5Z)-N-(4-Chlorophenyl)-2,3-dimethyl-1,2,4-thiadiazol-5(2H)-imine chemical structure, C10H10ClN3S, CAS 89476-27-7
(5Z)-N-(4-Chlorophenyl)-2,3-dimethyl-1,2,4-thiadiazol-5(2H)-imine
CAS 89476-27-7C10H10ClN3S
3-Bromo-N-(4-bromophenyl)-1,2,4-thiadiazol-5-amine chemical structure, C8H5Br2N3S, CAS 112178-66-2
3-Bromo-N-(4-bromophenyl)-1,2,4-thiadiazol-5-amine
CAS 112178-66-2C8H5Br2N3S
1,3-Propanediamine, N1-(3-fluorophenyl)-N1-[3-(1-methylethyl)-1,2,4-thiadiazol-5-yl]- chemical structure, C14H19FN4S, CAS 1467128-55-7
1,3-Propanediamine, N1-(3-fluorophenyl)-N1-[3-(1-methylethyl)-1,2,4-thiadiazol-5-yl]-
CAS 1467128-55-7C14H19FN4S
N-(4-Chlorophenyl)-3-[2-(methylamino)propyl]-1,2,4-thiadiazol-5-amine chemical structure, C12H15ClN4S, CAS 1371630-64-6
N-(4-Chlorophenyl)-3-[2-(methylamino)propyl]-1,2,4-thiadiazol-5-amine
CAS 1371630-64-6C12H15ClN4S
1-(5-((2-Fluorophenyl)amino)-1,2,4-thiadiazol-3-yl)propan-2-one chemical structure, C11H10FN3OS, CAS 1707372-91-5
1-(5-((2-Fluorophenyl)amino)-1,2,4-thiadiazol-3-yl)propan-2-one
CAS 1707372-91-5C11H10FN3OS
1-(5-((3-Fluorophenyl)amino)-1,2,4-thiadiazol-3-yl)propan-2-one chemical structure, C11H10FN3OS, CAS 1955518-01-0
1-(5-((3-Fluorophenyl)amino)-1,2,4-thiadiazol-3-yl)propan-2-one
CAS 1955518-01-0C11H10FN3OS
3-Methyl-N-(2-methylphenyl)-1,2,4-thiadiazol-5-amine chemical structure, C10H11N3S, CAS 21734-88-3
3-Methyl-N-(2-methylphenyl)-1,2,4-thiadiazol-5-amine
CAS 21734-88-3C10H11N3S
1,2,4-Thiadiazole-3-carboximidamide, N-hydroxy-5-(phenylamino)- chemical structure, C9H9N5OS, CAS 141540-09-2
1,2,4-Thiadiazole-3-carboximidamide, N-hydroxy-5-(phenylamino)-
CAS 141540-09-2C9H9N5OS
3-(1-Nitrosoethylidene)-N-phenyl-2,3-dihydro-1,2,4-thiadiazol-5-amine chemical structure, C10H10N4OS, CAS 64822-05-5
3-(1-Nitrosoethylidene)-N-phenyl-2,3-dihydro-1,2,4-thiadiazol-5-amine
CAS 64822-05-5C10H10N4OS
(NZ)-N-[1-(5-anilino-1,2,4-thiadiazol-3-yl)ethylidene]hydroxylamine chemical structure, C10H10N4OS
(NZ)-N-[1-(5-anilino-1,2,4-thiadiazol-3-yl)ethylidene]hydroxylamine
C10H10N4OS
N5-(2,6-difluorophenyl)-1,2,4-thiadiazole-3,5-diamine chemical structure, C8H6F2N4S, CAS 1872273-76-1
N5-(2,6-difluorophenyl)-1,2,4-thiadiazole-3,5-diamine
CAS 1872273-76-1C8H6F2N4S