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Murcko scaffold

Ring system with 2 rings and 17 atoms

95 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
95
With full pages
12
Scaffold SMILES

O=C(C=Cc1ccccc1)NC1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)NC1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 95 chemicals

(2E)-3-(4-Chlorophenyl)-N-cyclohexylprop-2-enamide chemical structure, C15H18ClNO, CAS 124525-56-0
(2E)-3-(4-Chlorophenyl)-N-cyclohexylprop-2-enamide
CAS 124525-56-0C15H18ClNO
(2E)-3-(2-Chlorophenyl)-N-cyclohexylprop-2-enamide chemical structure, C15H18ClNO, CAS 124525-31-1
(2E)-3-(2-Chlorophenyl)-N-cyclohexylprop-2-enamide
CAS 124525-31-1C15H18ClNO
(2E)-3-(2-Chlorophenyl)-N-cyclohexyl-N-methylprop-2-enamide chemical structure, C16H20ClNO, CAS 300825-47-2
(2E)-3-(2-Chlorophenyl)-N-cyclohexyl-N-methylprop-2-enamide
CAS 300825-47-2C16H20ClNO
N-Cyclohexyl-3-(3,4,5-trimethoxy-phenyl)-acrylamide chemical structure, C18H25NO4, CAS 154235-52-6
N-Cyclohexyl-3-(3,4,5-trimethoxy-phenyl)-acrylamide
CAS 154235-52-6C18H25NO4
N-Cyclohexyl-3-(4-isopropylphenyl)acrylamide chemical structure, C18H25NO, CAS 1164504-51-1
N-Cyclohexyl-3-(4-isopropylphenyl)acrylamide
CAS 1164504-51-1C18H25NO
(E)-2-Cyano-N-cyclohexyl-3-(3-hydroxyphenyl)acrylamide chemical structure, C16H18N2O2, CAS 351893-99-7
(E)-2-Cyano-N-cyclohexyl-3-(3-hydroxyphenyl)acrylamide
CAS 351893-99-7C16H18N2O2
(2E)-2-Cyano-N-cyclohexyl-3-(4-hydroxyphenyl)acrylamide chemical structure, C16H18N2O2, CAS 351894-04-7
(2E)-2-Cyano-N-cyclohexyl-3-(4-hydroxyphenyl)acrylamide
CAS 351894-04-7C16H18N2O2
(2E)-3-(2-Chlorophenyl)-N-cyclohexyl-N-ethylprop-2-enamide chemical structure, C17H22ClNO, CAS 6599-05-9
(2E)-3-(2-Chlorophenyl)-N-cyclohexyl-N-ethylprop-2-enamide
CAS 6599-05-9C17H22ClNO
(E)-N-Cyclohexyl-N-ethyl-3-phenylprop-2-enamide chemical structure, C17H23NO, CAS 349433-22-3
(E)-N-Cyclohexyl-N-ethyl-3-phenylprop-2-enamide
CAS 349433-22-3C17H23NO
(E)-3-(2-Chloro-6-fluorophenyl)-N-cyclohexylprop-2-enamide chemical structure, C15H17ClFNO, CAS 544411-15-6
(E)-3-(2-Chloro-6-fluorophenyl)-N-cyclohexylprop-2-enamide
CAS 544411-15-6C15H17ClFNO
(2E)-3-(3-Bromo-4-methoxyphenyl)-N-cyclohexyl-N-methylprop-2-enamide chemical structure, C17H22BrNO2, CAS 302574-18-1
(2E)-3-(3-Bromo-4-methoxyphenyl)-N-cyclohexyl-N-methylprop-2-enamide
CAS 302574-18-1C17H22BrNO2
2-Cyano-N-cyclohexyl-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enamide chemical structure, C18H22N2O4, CAS 473233-24-8
2-Cyano-N-cyclohexyl-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enamide
CAS 473233-24-8C18H22N2O4
N-(4-Ethylcyclohexyl)-3-(2-fluorophenyl)-2-propenamide chemical structure, C17H22FNO, CAS 667436-80-8
N-(4-Ethylcyclohexyl)-3-(2-fluorophenyl)-2-propenamide
CAS 667436-80-8C17H22FNO
Methyl 4-[2-cyano-2-(cyclohexylcarbamoyl)eth-1-en-1-yl]benzoate chemical structure, C18H20N2O3, CAS 340287-12-9
Methyl 4-[2-cyano-2-(cyclohexylcarbamoyl)eth-1-en-1-yl]benzoate
CAS 340287-12-9C18H20N2O3
2-Cyano-N-cyclohexyl-3-[4-(difluoromethoxy)phenyl]prop-2-enamide chemical structure, C17H18F2N2O2, CAS 326620-07-9
2-Cyano-N-cyclohexyl-3-[4-(difluoromethoxy)phenyl]prop-2-enamide
CAS 326620-07-9C17H18F2N2O2
2-Cyano-N-cyclohexyl-3-(3,4-difluorophenyl)prop-2-enamide chemical structure, C16H16F2N2O, CAS 1164546-99-9
2-Cyano-N-cyclohexyl-3-(3,4-difluorophenyl)prop-2-enamide
CAS 1164546-99-9C16H16F2N2O
2-Cyano-N-cyclohexyl-3-(4-ethylphenyl)prop-2-enamide chemical structure, C18H22N2O, CAS 380556-92-3
2-Cyano-N-cyclohexyl-3-(4-ethylphenyl)prop-2-enamide
CAS 380556-92-3C18H22N2O
2-Cyano-N-cyclohexyl-3-(3-methylphenyl)prop-2-enamide chemical structure, C17H20N2O, CAS 380570-40-1
2-Cyano-N-cyclohexyl-3-(3-methylphenyl)prop-2-enamide
CAS 380570-40-1C17H20N2O
2-Cyano-N-cyclohexyl-3-[2-(difluoromethoxy)phenyl]prop-2-enamide chemical structure, C17H18F2N2O2, CAS 717136-00-0
2-Cyano-N-cyclohexyl-3-[2-(difluoromethoxy)phenyl]prop-2-enamide
CAS 717136-00-0C17H18F2N2O2
2-Cyano-N-cyclohexyl-3-[4-(trifluoromethyl)phenyl]prop-2-enamide chemical structure, C17H17F3N2O, CAS 457075-89-7
2-Cyano-N-cyclohexyl-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
CAS 457075-89-7C17H17F3N2O
2-Cyano-N-cyclohexyl-3-(3,4-dihydroxyphenyl)prop-2-enamide chemical structure, C16H18N2O3, CAS 133550-44-4
2-Cyano-N-cyclohexyl-3-(3,4-dihydroxyphenyl)prop-2-enamide
CAS 133550-44-4C16H18N2O3
2-Cyano-N-cyclohexyl-3-[2-(trifluoromethyl)phenyl]prop-2-enamide chemical structure, C17H17F3N2O, CAS 750618-34-9
2-Cyano-N-cyclohexyl-3-[2-(trifluoromethyl)phenyl]prop-2-enamide
CAS 750618-34-9C17H17F3N2O
2-Cyano-N-cyclohexyl-3-(2,3,4,5,6-pentafluorophenyl)prop-2-enamide chemical structure, C16H13F5N2O, CAS 452292-56-7
2-Cyano-N-cyclohexyl-3-(2,3,4,5,6-pentafluorophenyl)prop-2-enamide
CAS 452292-56-7C16H13F5N2O
2-Cyano-N-cyclohexyl-3-(4-acetamidophenyl)prop-2-enamide chemical structure, C18H21N3O2, CAS 722473-04-3
2-Cyano-N-cyclohexyl-3-(4-acetamidophenyl)prop-2-enamide
CAS 722473-04-3C18H21N3O2