Murcko scaffold
3-Morpholinone scaffold
211 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 7
- Chemicals
- 211
- With full pages
- 43
Scaffold SMILES
O=C1COCCN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 211 chemicals
3-Morpholinone
CAS 109-11-5C4H7NO2
Muramic lactam
CAS 35477-93-1C9H15NO6
3-Morpholinone, 2-hydroxy-2,5,5-trimethyl-
CAS 53153-49-4C7H13NO3
tert-Butyl 3-butan-2-yl-5-oxomorpholine-4-carboxylate
C13H23NO4
6-(Aminomethyl)morpholin-3-one
CAS 793644-35-6C5H10N2O2
4-Methylmorpholin-3-one
CAS 20721-78-2C5H9NO2
(S)-6-(Hydroxymethyl)morpholin-3-one
CAS 847805-30-5C5H9NO3
(5R)-5-Methylmorpholin-3-one
CAS 119844-67-6C5H9NO2
(5S)-5-Methylmorpholin-3-one
CAS 119844-66-5C5H9NO2
5-Methylmorpholin-3-one
CAS 65922-85-2C5H9NO2
Ethyl 2-methyl-5-oxomorpholine-3-carboxylate
CAS 83485-90-9C8H13NO4
4-Butyl-5-hydroxymorpholin-3-one
CAS 88460-83-7C8H15NO3
4-Butyl-5-(2-oxopropyl)morpholin-3-one
CAS 88460-92-8C11H19NO3
2-Methyl-3-morpholinone
CAS 13882-80-9C5H9NO2
(2R)-2-Methylmorpholin-3-one
CAS 100636-23-5C5H9NO2
(S)-2-Methylmorpholin-3-one
CAS 129779-18-6C5H9NO2
2-(3-Oxomorpholino)acetonitrile
CAS 426818-00-0C6H8N2O2
2,6-Dimethylmorpholin-3-one
CAS 93240-61-0C6H11NO2
(2R,6R)-2,6-Dimethylmorpholin-3-one
CAS 117465-49-3C6H11NO2
(6S)-2,6-Dimethylmorpholin-3-one
CAS 1643811-22-6C6H11NO2
6-Methyl-4-propan-2-ylmorpholin-3-one
CAS 121923-44-2C8H15NO2
4-Dodecyl-5-methyl-3-morpholinone
CAS 116354-63-3C17H33NO2
tert-Butyl 3-oxomorpholine-4-carboxylate
CAS 142929-48-4C9H15NO4
5-Ethylmorpholin-3-one
CAS 77605-88-0C6H11NO2
- 4-{[Chloro(dimethyl)germyl]methyl}-5-ethylmorpholin-3-one144315-58-2C9H18ClGeNO2
- 4-[2-(Dimethylamino)ethyl]morpholin-3-one143244-87-5C8H16N2O2
- (5S)-5-(2-Methylpropyl)morpholin-3-one101250-44-6C8H15NO2
- 4-t-Boc-(5S)-5-[(1S)-methylpropyl]-morpholin-3-one160141-21-9C13H23NO4
- 4-(2-Hydroxyethyl)morpholin-3-one41036-01-5C6H11NO3
- 4-(2-Chloroethyl)morpholin-3-one186294-84-8C6H10ClNO2
- 4-(2-Bromoethyl)morpholin-3-one1501749-25-2C6H10BrNO2
- Ethyl 4-methyl-3-oxomorpholine-2-carboxylate96905-32-7C8H13NO4
- 4-Hydroxymorpholin-3-one19795-03-0C4H7NO3
- 5-Ethyl-2-methyl-3-morpholinone343307-35-7C7H13NO2
- 2,5,5-Trimethylmorpholin-3-one1011632-66-8C7H13NO2
- 1 suppliers6-Methylmorpholin-3-one127958-63-8C5H9NO2
- 1 suppliers5,5-Dimethylmorpholin-3-one127958-62-7C6H11NO2
- 5-(Propan-2-yl)morpholin-3-one127958-60-5C7H13NO2
- 5-(2-Methylpropyl)morpholin-3-one1849274-28-7C8H15NO2
- 4-Methyl-3-oxomorpholine-2-carboxylic acid96905-33-8C6H9NO4
- 2-(2-Methyl-5-oxomorpholin-4-yl)acetonitrile426818-07-7C7H10N2O2
- 5-Oxomorpholine-3-carboxylic acid1367717-62-1C5H7NO4
- 4-Ethenylmorpholin-3-one28517-76-2C6H9NO2
- 6-(Aminomethyl)morpholin-3-one hydrochloride170799-36-7C5H11ClN2O2
- Methyl 5-(3-oxomorpholin-4-yl)pentanoate727736-43-8C10H17NO4
- 5-(3-Oxomorpholin-4-yl)pentanoic acid727736-39-2C9H15NO4
- 6-(Aminomethyl)-4-methyl-3-morpholinone956722-56-8C6H12N2O2
- 6-(Aminomethyl)-4-butylmorpholin-3-one1017113-10-8C9H18N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
