Murcko scaffold
Hexahydrocyclopenta[c]pyrrol-4(2H)-one scaffold
28 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 28
- With full pages
- 4
Scaffold SMILES
O=C1CCC2CNCC12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 28 of 28 chemicals
![cis-Hexahydro-cyclopenta[c]pyrrol-4-one chemical structure, C7H11NO, CAS 130658-11-6](/s/VTJCOTZQTGPOSP-NTSWFWBYSA-N.svg)
cis-Hexahydro-cyclopenta[c]pyrrol-4-one
CAS 130658-11-6C7H11NO
![Hexahydrocyclopenta[c]pyrrol-4(2H)-one chemical structure, C7H11NO, CAS 732956-04-6](/s/VTJCOTZQTGPOSP-UHFFFAOYSA-N.svg)
Hexahydrocyclopenta[c]pyrrol-4(2H)-one
CAS 732956-04-6C7H11NO
![rac-(3aR,6aS)-2-methyl-octahydrocyclopenta[c]pyrrol-4-one chemical structure, C8H13NO, CAS 180481-87-2](/s/BRYHFQMDNZZHSI-NKWVEPMBSA-N.svg)
rac-(3aR,6aS)-2-methyl-octahydrocyclopenta[c]pyrrol-4-one
CAS 180481-87-2C8H13NO
![Hexahydrocyclopenta[C]pyrrol-4(2H)-one hydrochloride chemical structure, C7H12ClNO, CAS 127430-46-0](/s/NCJPVPGXNDVUCM-UHFFFAOYSA-N.svg)
Hexahydrocyclopenta[C]pyrrol-4(2H)-one hydrochloride
CAS 127430-46-0C7H12ClNO
![cis-tert-Butyl 4-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate chemical structure, C12H19NO3, CAS 1701484-85-6](/s/MZQZNAQWIOWKSR-DTWKUNHWSA-N.svg)
cis-tert-Butyl 4-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
CAS 1701484-85-6C12H19NO3
![rel-1,1-Dimethylethyl (3aR,6aS)-hexahydro-4-oxocyclopenta[c]pyrrole-2(1H)-carboxylate chemical structure, C12H19NO3, CAS 130658-14-9](/s/MZQZNAQWIOWKSR-BDAKNGLRSA-N.svg)
rel-1,1-Dimethylethyl (3aR,6aS)-hexahydro-4-oxocyclopenta[c]pyrrole-2(1H)-carboxylate
CAS 130658-14-9C12H19NO3
![(3aR,6aS)-2,3,3a,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-4-one chemical structure, C7H11NO](/s/VTJCOTZQTGPOSP-RITPCOANSA-N.svg)
(3aR,6aS)-2,3,3a,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-4-one
C7H11NO
4-Oxo-hexahydro-cyclopenta(c)pyrrole-2-carboxylic acid tert-butyl ester
CAS 879686-42-7C12H19NO3
![(3AS,6aR)-2-isopropylhexahydrocyclopenta[c]pyrrol-4(2H)-one chemical structure, C10H17NO, CAS 180482-20-6](/s/NQBXESNRBIJGDN-DTWKUNHWSA-N.svg)
(3AS,6aR)-2-isopropylhexahydrocyclopenta[c]pyrrol-4(2H)-one
CAS 180482-20-6C10H17NO
![(3AS,6aR)-2-ethylhexahydrocyclopenta[c]pyrrol-4(2H)-one chemical structure, C9H15NO, CAS 180482-18-2](/s/MOQDBMYDVNXJIF-JGVFFNPUSA-N.svg)
(3AS,6aR)-2-ethylhexahydrocyclopenta[c]pyrrol-4(2H)-one
CAS 180482-18-2C9H15NO
![2-Methyl-octahydrocyclopenta[c]pyrrol-4-one chemical structure, C8H13NO, CAS 2098026-80-1](/s/BRYHFQMDNZZHSI-UHFFFAOYSA-N.svg)
2-Methyl-octahydrocyclopenta[c]pyrrol-4-one
CAS 2098026-80-1C8H13NO
![4-Oxooctahydrocyclopenta[c]pyrrole-1-carboxylic acid hydrochloride chemical structure, C8H12ClNO3, CAS 783325-84-8](/s/RKANTXGTMRSPRR-UHFFFAOYSA-N.svg)
4-Oxooctahydrocyclopenta[c]pyrrole-1-carboxylic acid hydrochloride
CAS 783325-84-8C8H12ClNO3
![4-Oxo-octahydro-cyclopenta[c]-pyrrole-1-carboxylic acid chemical structure, C8H11NO3, CAS 794501-16-9](/s/CDEVOFDMWGXHJR-UHFFFAOYSA-N.svg)
4-Oxo-octahydro-cyclopenta[c]-pyrrole-1-carboxylic acid
CAS 794501-16-9C8H11NO3
![rac-2-tert-butyl 1-ethyl (1R,3aS,6aR)-4-oxo-octahydrocyclopenta[c]pyrrole-1,2-dicarboxylate chemical structure, C15H23NO5, CAS 1648739-43-8](/s/LMRREUVKWATQOD-NHCYSSNCSA-N.svg)
rac-2-tert-butyl 1-ethyl (1R,3aS,6aR)-4-oxo-octahydrocyclopenta[c]pyrrole-1,2-dicarboxylate
CAS 1648739-43-8C15H23NO5
![6-Oxooctahydrocyclopenta[c]pyrrole-1-carboxylic acid chemical structure, C8H11NO3, CAS 1403766-60-8](/s/STOPKANNBIWSML-UHFFFAOYSA-N.svg)
6-Oxooctahydrocyclopenta[c]pyrrole-1-carboxylic acid
CAS 1403766-60-8C8H11NO3
![2-[(tert-Butoxy)carbonyl]-6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid chemical structure, C13H19NO5, CAS 2416229-08-6](/s/YPFVTZKKCQAULR-UHFFFAOYSA-N.svg)
2-[(tert-Butoxy)carbonyl]-6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid
CAS 2416229-08-6C13H19NO5
![cis-Hexahydro-cyclopenta[c]pyrrol-4-onehydrochloride chemical structure, C7H12ClNO](/s/NCJPVPGXNDVUCM-IBTYICNHSA-N.svg)
cis-Hexahydro-cyclopenta[c]pyrrol-4-onehydrochloride
C7H12ClNO
![cis-Hexahydro-cyclopenta[c]pyrrol-4-one hydrochloride chemical structure, C7H12ClNO, CAS 130657-48-6](/s/NCJPVPGXNDVUCM-RIHPBJNCSA-N.svg)
cis-Hexahydro-cyclopenta[c]pyrrol-4-one hydrochloride
CAS 130657-48-6C7H12ClNO
![Methyl 6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylate chemical structure, C9H13NO3, CAS 2580209-41-0](/s/UFWBKLFWZIVQEP-UHFFFAOYSA-N.svg)
Methyl 6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylate
CAS 2580209-41-0C9H13NO3
![tert-Butyl 6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylate chemical structure, C12H19NO3, CAS 2580236-88-8](/s/WPFIJGCPJZLFHA-UHFFFAOYSA-N.svg)
tert-Butyl 6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylate
CAS 2580236-88-8C12H19NO3
![Ethyl 6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylate chemical structure, C10H15NO3, CAS 2580218-38-6](/s/DWJPGWXCVJIWDP-UHFFFAOYSA-N.svg)
Ethyl 6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylate
CAS 2580218-38-6C10H15NO3
![6-Oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid chemical structure, C8H11NO3, CAS 2580197-26-6](/s/ADIGWUJAYAWMKB-UHFFFAOYSA-N.svg)
6-Oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid
CAS 2580197-26-6C8H11NO3
![2-Acetyl-6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid chemical structure, C10H13NO4, CAS 2680829-45-0](/s/JCJDNDUZZQCVQT-UHFFFAOYSA-N.svg)
2-Acetyl-6-oxo-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid
CAS 2680829-45-0C10H13NO4
![6-Oxo-2-(2,2,2-trifluoroacetyl)-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid chemical structure, C10H10F3NO4, CAS 2680825-82-3](/s/JYFSXVWSAZZMMP-UHFFFAOYSA-N.svg)
6-Oxo-2-(2,2,2-trifluoroacetyl)-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid
CAS 2680825-82-3C10H10F3NO4
- rac-Ethyl (1R,3aS,6aR)-4-oxo-octahydrocyclopenta[c]pyrrole-1-carboxylate1648782-42-6C10H15NO3
- 6-Oxo-2-[(prop-2-en-1-yloxy)carbonyl]-octahydrocyclopenta[c]pyrrole-3a-carboxylic acid2680882-28-2C12H15NO5
- (3aR,6aS)-Octahydrocyclopenta[c]pyrrol-4-one2416991-38-1C14H22N2O2
- rac-(1R,3aS,6aR)-2-[(tert-butoxy)carbonyl]-4-oxo-octahydrocyclopenta[c]pyrrole-1-carboxylic acid2973403-64-2C13H19NO5
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