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Murcko scaffold

Ring system with 2 rings and 13 atoms

138 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
138
With full pages
16
Scaffold SMILES

O=C1C=CCC(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CCC(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 138 chemicals

3-Methyl-5-phenylcyclohex-2-en-1-one chemical structure, C13H14O, CAS 5337-88-2
3-Methyl-5-phenylcyclohex-2-en-1-one
CAS 5337-88-2C13H14O
Dimethyl 4-methyl-6-oxo-2-phenylcyclohex-4-ene-1,3-dicarboxylate chemical structure, C17H18O5, CAS 94445-20-2
Dimethyl 4-methyl-6-oxo-2-phenylcyclohex-4-ene-1,3-dicarboxylate
CAS 94445-20-2C17H18O5
3-Chloro-5-(4-chlorophenyl)cyclohex-2-en-1-one chemical structure, C12H10Cl2O, CAS 54898-64-5
3-Chloro-5-(4-chlorophenyl)cyclohex-2-en-1-one
CAS 54898-64-5C12H10Cl2O
3-Chloro-5-(4-methoxyphenyl)cyclohex-2-en-1-one chemical structure, C13H13ClO2, CAS 61888-41-3
3-Chloro-5-(4-methoxyphenyl)cyclohex-2-en-1-one
CAS 61888-41-3C13H13ClO2
3-Chloro-5-(2,4-dichlorophenyl)cyclohex-2-en-1-one chemical structure, C12H9Cl3O, CAS 61888-44-6
3-Chloro-5-(2,4-dichlorophenyl)cyclohex-2-en-1-one
CAS 61888-44-6C12H9Cl3O
3-Amino-5-(4-chlorophenyl)cyclohex-2-en-1-one chemical structure, C12H12ClNO, CAS 478064-04-9
3-Amino-5-(4-chlorophenyl)cyclohex-2-en-1-one
CAS 478064-04-9C12H12ClNO
tert-Butyl N-[(3-oxo-5-phenylcyclohexen-1-yl)amino]carbamate chemical structure, C17H22N2O3, CAS 6035-58-1
tert-Butyl N-[(3-oxo-5-phenylcyclohexen-1-yl)amino]carbamate
CAS 6035-58-1C17H22N2O3
3-(Isopentylamino)-5-(4-methoxyphenyl)-2-cyclohexen-1-one chemical structure, C18H25NO2, CAS 332861-64-0
3-(Isopentylamino)-5-(4-methoxyphenyl)-2-cyclohexen-1-one
CAS 332861-64-0C18H25NO2
3-Hydroxy-5-(4-methylphenyl)cyclohex-2-en-1-one chemical structure, C13H14O2, CAS 354539-08-5
3-Hydroxy-5-(4-methylphenyl)cyclohex-2-en-1-one
CAS 354539-08-5C13H14O2
3-Isobutylamino-5-p-tolyl-cyclohex-2-enone chemical structure, C17H23NO, CAS 333325-95-4
3-Isobutylamino-5-p-tolyl-cyclohex-2-enone
CAS 333325-95-4C17H23NO
3-Hydroxy-5-(3,4,5-trimethoxyphenyl)cyclohex-2-en-1-one chemical structure, C15H18O5, CAS 355430-59-0
3-Hydroxy-5-(3,4,5-trimethoxyphenyl)cyclohex-2-en-1-one
CAS 355430-59-0C15H18O5
N,N-Dimethyl-N'-(3-oxo-5-phenyl-1-cyclohexen-1-yl)methanimidamide chemical structure, C15H18N2O, CAS 131929-03-8
N,N-Dimethyl-N'-(3-oxo-5-phenyl-1-cyclohexen-1-yl)methanimidamide
CAS 131929-03-8C15H18N2O
N,N-Dimethyl-N'-(3-oxo-5-phenyl-1-cyclohexen-1-yl)ethanimidamide chemical structure, C16H20N2O, CAS 131929-06-1
N,N-Dimethyl-N'-(3-oxo-5-phenyl-1-cyclohexen-1-yl)ethanimidamide
CAS 131929-06-1C16H20N2O
3-Hydroxy-5-phenylcyclohex-2-en-1-one chemical structure, C12H12O2, CAS 35376-44-4
3-Hydroxy-5-phenylcyclohex-2-en-1-one
CAS 35376-44-4C12H12O2
5-(4-Chlorophenyl)-3-hydroxycyclohex-2-en-1-one chemical structure, C12H11ClO2, CAS 373370-03-7
5-(4-Chlorophenyl)-3-hydroxycyclohex-2-en-1-one
CAS 373370-03-7C12H11ClO2
Methyl 4-hydroxy-2-oxo-6-phenylcyclohex-3-ene-1-carboxylate chemical structure, C14H14O4, CAS 151777-66-1
Methyl 4-hydroxy-2-oxo-6-phenylcyclohex-3-ene-1-carboxylate
CAS 151777-66-1C14H14O4
5-(3,4-Dimethoxyphenyl)-3-(heptylamino)cyclohex-2-en-1-one chemical structure, C21H31NO3, CAS 351164-40-4
5-(3,4-Dimethoxyphenyl)-3-(heptylamino)cyclohex-2-en-1-one
CAS 351164-40-4C21H31NO3
3-Hydroxy-5-(4-methoxyphenyl)cyclohex-2-en-1-one chemical structure, C13H14O3, CAS 111945-85-8
3-Hydroxy-5-(4-methoxyphenyl)cyclohex-2-en-1-one
CAS 111945-85-8C13H14O3
3-Chloro-5-phenylcyclohex-2-en-1-one chemical structure, C12H11ClO, CAS 51367-64-7
3-Chloro-5-phenylcyclohex-2-en-1-one
CAS 51367-64-7C12H11ClO
2-Cyclohexene-1-carboxylic acid, 6-(2-chlorophenyl)-2-hydroxy-4-oxo-, ethyl ester chemical structure, C15H15ClO4, CAS 133132-27-1
2-Cyclohexene-1-carboxylic acid, 6-(2-chlorophenyl)-2-hydroxy-4-oxo-, ethyl ester
CAS 133132-27-1C15H15ClO4
2-Cyclohexene-1-carboxylic acid, 6-(2,6-dichlorophenyl)-2-hydroxy-4-oxo-, ethyl ester chemical structure, C15H14Cl2O4, CAS 1027055-05-5
2-Cyclohexene-1-carboxylic acid, 6-(2,6-dichlorophenyl)-2-hydroxy-4-oxo-, ethyl ester
CAS 1027055-05-5C15H14Cl2O4
3-Amino-5-phenyl-2-cyclohexen-1-one chemical structure, C12H13NO, CAS 36646-70-5
3-Amino-5-phenyl-2-cyclohexen-1-one
CAS 36646-70-5C12H13NO
4'-Hydroxy-5-methyl-1,6-dihydro[1,1'-biphenyl]-3(2H)-one chemical structure, C13H14O2, CAS 62596-09-2
4'-Hydroxy-5-methyl-1,6-dihydro[1,1'-biphenyl]-3(2H)-one
CAS 62596-09-2C13H14O2
3-Methoxy-5-methyl-5-phenyl-2-cyclohexen-1-one chemical structure, C14H16O2, CAS 75895-55-5
3-Methoxy-5-methyl-5-phenyl-2-cyclohexen-1-one
CAS 75895-55-5C14H16O2