Murcko scaffold
2-Phenyl-N-(piperidin-4-yl)acetamide scaffold
50 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 50
- With full pages
- 4
Scaffold SMILES
O=C(Cc1ccccc1)NC1CCNCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 50 chemicals
2-(4-Methoxyphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)acetamide
CAS 426239-99-8C18H28N2O2
2-Phenyl-N-(piperidin-4-yl)acetamide
CAS 75484-47-8C13H18N2O
3,4-Diethoxy-N-(1,2,2,6,6-pentamethyl-4-piperidinyl)benzeneacetamide
CAS 681837-32-1C22H36N2O3
2-(2-Chloro-6-fluorophenyl)-N-(1-methylpiperidin-4-yl)acetamide
CAS 777872-77-2C14H18ClFN2O
2-(2-Methoxyphenyl)-N-(1-methylpiperidin-4-yl)acetamide
CAS 915888-48-1C15H22N2O2
2-(2-Methoxyphenyl)-N-(1-propylpiperidin-4-yl)acetamide
CAS 915900-96-8C17H26N2O2
Benzeneacetamide, 2-fluoro-N-4-piperidinyl-
CAS 309251-30-7C13H17FN2O
N-Ethyl-2-(4-methanesulfonyl-phenyl)-N-piperidin-4-yl-acetamide
CAS 374725-04-9C16H24N2O3S
N-[1-(3-Chloropropyl)piperidin-4-yl]-2-phenylacetamide
CAS 77196-99-7C16H23ClN2O
2-(4-Fluorophenyl)-N-piperidin-4-ylacetamide
CAS 198210-55-8C13H17FN2O
4-Methoxy-N-methyl-N-4-piperidinylbenzeneacetamide
CAS 277745-26-3C15H22N2O2
2-(4-Chlorophenyl)-N-(piperidin-4-yl)acetamide hydrochloride
CAS 1829598-29-9C13H18Cl2N2O
2-(2-Fluorophenyl)-N-[1-(propan-2-yl)piperidin-4-yl]acetamide
CAS 959239-88-4C16H23FN2O
2-Phenyl-N-[1-(propan-2-yl)piperidin-4-yl]acetamide
CAS 959242-49-0C16H24N2O
2-(4-Chlorophenyl)-N-(1-methylpiperidin-4-yl)acetamide
CAS 959240-49-4C14H19ClN2O
2-(3,4-Dichlorophenyl)-N-(1-methylpiperidin-4-yl)acetamide
CAS 959246-80-1C14H18Cl2N2O
2-(4-Ethoxyphenyl)-N-(1-methylpiperidin-4-yl)acetamide
CAS 959239-66-8C16H24N2O2
4-Fluoro-N-methyl-N-(1-methyl-4-piperidinyl)benzeneacetamide
CAS 1090469-34-3C15H21FN2O
2-Phenyl-N-(piperidin-4-yl)acetamide hydrochloride
CAS 1170480-78-0C13H19ClN2O
2-(4-Hydroxyphenyl)-N-(piperidin-4-yl)acetamide
CAS 1097827-25-2C13H18N2O2
2-Amino-N-(1-ethylpiperidin-4-yl)-N-methyl-2-phenylacetamide
CAS 1218515-30-0C16H25N3O
N-Methyl-N-4-piperidinyl-benzeneacetamide
CAS 868764-37-8C14H20N2O
4-[2-(4-Chloro-phenyl)-acetylamino]-piperidine-1-carboxylic acid tert-butyl ester
CAS 278598-15-5C18H25ClN2O3
2-(3,4-Dimethoxyphenyl)-N-[1-(2-methoxyethyl)piperidin-4-yl]acetamide
CAS 1421490-50-7C18H28N2O4
- N-[1-(2-Methoxyethyl)piperidin-4-yl]-2-phenylbutanamide1421484-69-6C18H28N2O2
- 2-(4-Chlorophenyl)-N-[1-(2-methoxyethyl)piperidin-4-yl]acetamide1421459-02-0C16H23ClN2O2
- 2-(4-Fluorophenyl)-N-(1-(2-methoxyethyl)piperidin-4-yl)acetamide1421497-07-5C16H23FN2O2
- 2-(2-Chlorophenyl)-N-[1-(2-methoxyethyl)piperidin-4-yl]acetamide1421510-22-6C16H23ClN2O2
- N-[1-(2-Methoxyethyl)piperidin-4-yl]-2-(3-methoxyphenyl)acetamide1421450-62-5C17H26N2O3
- 4-[2-(4-Bromo-phenyl)acetylamino]-piperidine-1-carboxylic acid tert-butyl ester1334001-49-8C18H25BrN2O3
- N-(4-Cyano-1-methylpiperidin-4-yl)-2-[4-(2-methylpropoxy)phenyl]acetamide1355932-06-7C19H27N3O2
- N-Boc 4-{[(2-bromo-4-cyanophenyl)acetyl]amino}piperidine1134198-30-3C19H24BrN3O3
- 2-(4-Chloro-phenyl)-N-ethyl-N-piperidin-4-yl-acetamide1015171-50-2C15H21ClN2O
- N-(4-Cyano-1-methylpiperidin-4-yl)-2-(3,4-dichlorophenyl)acetamide1427963-41-4C15H17Cl2N3O
- tert-Butyl 4-(n-ethyl-2-(4-(methylsulfonyl)phenyl)acetamido)-4-methylpiperidine-1-carboxylate872850-51-6C22H34N2O5S
- tert-Butyl 4-(2-(4-(methylsulfonyl)phenyl)acetamido)-4-ethylpiperidine-1-carboxylate872850-42-5C21H32N2O5S
- 2-Amino-N-(1-ethylpiperidin-4-yl)-N-methyl-2-phenylacetamide dihydrochloride1423028-73-2C16H27Cl2N3O
- N-(1-(2-Methoxyethyl)piperidin-4-yl)-2-(4-methoxyphenyl)acetamide formate1421452-62-1C18H28N2O5
- 2-(4-Ethoxyphenyl)-N-[1-(2-methoxyethyl)piperidin-4-yl]acetamide1421469-62-6C18H28N2O3
- N-(1-(2-Methoxyethyl)piperidin-4-yl)-2-(m-tolyl)acetamide1421514-28-4C17H26N2O2
- N-(4-Cyano-1-methylpiperidin-4-yl)-2-(2,5-difluorophenyl)acetamide1436332-95-4C15H17F2N3O
- Benzeneacetamide, 2-(aminomethyl)-N-[1-(1-methylethyl)-4-piperidinyl]-1511936-22-3C17H27N3O
- 2-(3-Bromophenyl)-N-(piperidin-4-yl)acetamide hydrochloride1838897-78-1C13H18BrClN2O
- 2-(2-Chlorophenyl)-N-(piperidin-4-yl)acetamide hydrochloride1830464-46-4C13H18Cl2N2O
- N-(4-Methylpiperidin-4-yl)-2-phenylacetamide hydrochloride2038581-24-5C14H21ClN2O
- Methyl (E)-4-oxo-4-[4-[(2-phenylacetyl)amino]piperidin-1-yl]but-2-enoate2411323-30-1C18H22N2O4
- Benzeneacetamide, 4-chloro-N-(1,3-dimethyl-4-piperidinyl)-, trans-30648-82-9C15H21ClN2O
- tert-Butyl 4-[2-(4-hydroxyphenyl)acetamido]piperidine-1-carboxylate2413875-25-7C18H26N2O4