CompoundList
Sign in
Murcko scaffold

3-(Thiophen-3-yl)pyrrolidine scaffold

127 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
127
With full pages
3
Scaffold SMILES

c1cc(C2CCNC2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(Thiophen-3-yl)pyrrolidine page
Murcko scaffold c1cc(C2CCNC2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 127 chemicals

(3S,4R)-4-Thiophen-3-ylpyrrolidine-3-carboxylic acid, hydrochloride chemical structure, C9H12ClNO2S, CAS 1049740-39-7
(3S,4R)-4-Thiophen-3-ylpyrrolidine-3-carboxylic acid, hydrochloride
CAS 1049740-39-7C9H12ClNO2S
rac-(3R,4S)-4-(Thiophen-3-yl)pyrrolidine-3-carboxylic acid chemical structure, C9H11NO2S, CAS 1049980-51-9
rac-(3R,4S)-4-(Thiophen-3-yl)pyrrolidine-3-carboxylic acid
CAS 1049980-51-9C9H11NO2S
(3S,4R)-1-tert-Butoxycarbonyl-4-(3-thienyl)pyrrolidine-3-carboxylic acid chemical structure, C14H19NO4S, CAS 959579-56-7
(3S,4R)-1-tert-Butoxycarbonyl-4-(3-thienyl)pyrrolidine-3-carboxylic acid
CAS 959579-56-7C14H19NO4S
Pyrrolidine, 1,3-dimethyl-3-(3-thienyl)-, (Z)-2-butenedioate chemical structure, C14H19NO4S, CAS 73604-78-1
Pyrrolidine, 1,3-dimethyl-3-(3-thienyl)-, (Z)-2-butenedioate
CAS 73604-78-1C14H19NO4S
3-(Thiophen-3-yl)pyrrolidine chemical structure, C8H11NS, CAS 1231907-58-6
3-(Thiophen-3-yl)pyrrolidine
CAS 1231907-58-6C8H11NS
[4-(Thiophen-3-yl)pyrrolidin-3-yl]methanol chemical structure, C9H13NOS, CAS 1379213-66-7
[4-(Thiophen-3-yl)pyrrolidin-3-yl]methanol
CAS 1379213-66-7C9H13NOS
4-(Thiophen-3-yl)pyrrolidine-3-carboxylic acid chemical structure, C9H11NO2S, CAS 1047655-28-6
4-(Thiophen-3-yl)pyrrolidine-3-carboxylic acid
CAS 1047655-28-6C9H11NO2S
1-[(tert-Butoxy)carbonyl]-4-(thiophen-3-yl)pyrrolidine-3-carboxylic acid chemical structure, C14H19NO4S, CAS 1366938-05-7
1-[(tert-Butoxy)carbonyl]-4-(thiophen-3-yl)pyrrolidine-3-carboxylic acid
CAS 1366938-05-7C14H19NO4S
2-Methyl-4-(thiophen-3-yl)pyrrolidine chemical structure, C9H13NS, CAS 1343254-15-8
2-Methyl-4-(thiophen-3-yl)pyrrolidine
CAS 1343254-15-8C9H13NS
Boc-(+/-)-trans-4-(3-thienyl)-pyrrolidine-3-carboxylic acid chemical structure, C14H19NO4S, CAS 2765729-20-0
Boc-(+/-)-trans-4-(3-thienyl)-pyrrolidine-3-carboxylic acid
CAS 2765729-20-0C14H19NO4S
trans-4-(3-Thienyl)-3-pyrrolidinecarboxylic acid hydrochloride chemical structure, C9H12ClNO2S, CAS 1864003-47-3
trans-4-(3-Thienyl)-3-pyrrolidinecarboxylic acid hydrochloride
CAS 1864003-47-3C9H12ClNO2S
(3R,4S)-4-(3-Thienyl)pyrrolidine-3-carboxylic acid chemical structure, C9H11NO2S, CAS 1864003-46-2
(3R,4S)-4-(3-Thienyl)pyrrolidine-3-carboxylic acid
CAS 1864003-46-2C9H11NO2S
rac-Methyl (3R,4S)-4-(thiophen-3-yl)pyrrolidine-3-carboxylate chemical structure, C10H13NO2S, CAS 291289-15-1
rac-Methyl (3R,4S)-4-(thiophen-3-yl)pyrrolidine-3-carboxylate
CAS 291289-15-1C10H13NO2S
3-Methyl-3-(thiophen-3-yl)pyrrolidine chemical structure, C9H13NS, CAS 1251293-08-9
3-Methyl-3-(thiophen-3-yl)pyrrolidine
CAS 1251293-08-9C9H13NS
3-(2,5-Dimethylthiophen-3-yl)-2-ethyl-5-methylpyrrolidine chemical structure, C13H21NS, CAS 1341750-79-5
3-(2,5-Dimethylthiophen-3-yl)-2-ethyl-5-methylpyrrolidine
CAS 1341750-79-5C13H21NS
tert-Butyl 3-hydroxy-3-(thiophen-3-yl)pyrrolidine-1-carboxylate chemical structure, C13H19NO3S, CAS 1310427-34-9
tert-Butyl 3-hydroxy-3-(thiophen-3-yl)pyrrolidine-1-carboxylate
CAS 1310427-34-9C13H19NO3S
tert-Butyl 3-(2-bromothiophen-3-yl)-3-hydroxypyrrolidine-1-carboxylate chemical structure, C13H18BrNO3S, CAS 1310427-35-0
tert-Butyl 3-(2-bromothiophen-3-yl)-3-hydroxypyrrolidine-1-carboxylate
CAS 1310427-35-0C13H18BrNO3S
Methyl 4-(thiophen-3-yl)pyrrolidine-3-carboxylate chemical structure, C10H13NO2S, CAS 1804129-95-0
Methyl 4-(thiophen-3-yl)pyrrolidine-3-carboxylate
CAS 1804129-95-0C10H13NO2S
3-(5-Methylthiophen-3-yl)pyrrolidine chemical structure, C9H13NS, CAS 1260842-14-5
3-(5-Methylthiophen-3-yl)pyrrolidine
CAS 1260842-14-5C9H13NS
1-tert-Butyl 3-methyl 4-(thiophen-3-yl)pyrrolidine-1,3-dicarboxylate chemical structure, C15H21NO4S, CAS 1803599-23-6
1-tert-Butyl 3-methyl 4-(thiophen-3-yl)pyrrolidine-1,3-dicarboxylate
CAS 1803599-23-6C15H21NO4S
tert-Butyl 3-(hydroxymethyl)-4-(thiophen-3-yl)pyrrolidine-1-carboxylate chemical structure, C14H21NO3S, CAS 1366647-67-7
tert-Butyl 3-(hydroxymethyl)-4-(thiophen-3-yl)pyrrolidine-1-carboxylate
CAS 1366647-67-7C14H21NO3S
[4-(Thiophen-3-yl)pyrrolidin-3-yl]methanol hydrochloride chemical structure, C9H14ClNOS, CAS 1803604-81-0
[4-(Thiophen-3-yl)pyrrolidin-3-yl]methanol hydrochloride
CAS 1803604-81-0C9H14ClNOS
Methyl 4-(thiophen-3-yl)pyrrolidine-3-carboxylate hydrochloride chemical structure, C10H14ClNO2S, CAS 1803608-51-6
Methyl 4-(thiophen-3-yl)pyrrolidine-3-carboxylate hydrochloride
CAS 1803608-51-6C10H14ClNO2S
3-(4-Methylthiophen-3-yl)pyrrolidine chemical structure, C9H13NS, CAS 1260874-06-3
3-(4-Methylthiophen-3-yl)pyrrolidine
CAS 1260874-06-3C9H13NS