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Murcko scaffold

Ring system with 2 rings and 12 atoms

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
27
With full pages
6
Scaffold SMILES

c1ccc(Sc2cnns2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Sc2cnns2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

5-[(3,4-Dichlorophenyl)sulfanyl]-1,2,3-thiadiazole chemical structure, C8H4Cl2N2S2, CAS 338407-96-8
5-[(3,4-Dichlorophenyl)sulfanyl]-1,2,3-thiadiazole
CAS 338407-96-8C8H4Cl2N2S2
2-Chlorophenyl 4-methyl-1,2,3-thiadiazol-5-yl sulfide chemical structure, C9H7ClN2S2, CAS 338408-36-9
2-Chlorophenyl 4-methyl-1,2,3-thiadiazol-5-yl sulfide
CAS 338408-36-9C9H7ClN2S2
5-{[2-Nitro-4-(trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole chemical structure, C9H4F3N3O2S2, CAS 338409-86-2
5-{[2-Nitro-4-(trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole
CAS 338409-86-2C9H4F3N3O2S2
Neopentyl N-{5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazol-4-yl}carbamate chemical structure, C14H16ClN3O2S2, CAS 400074-50-2
Neopentyl N-{5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazol-4-yl}carbamate
CAS 400074-50-2C14H16ClN3O2S2
2-[(4-Methyl-1,2,3-thiadiazol-5-yl)sulfanyl]benzenecarboxylic acid chemical structure, C10H8N2O2S2, CAS 400082-02-2
2-[(4-Methyl-1,2,3-thiadiazol-5-yl)sulfanyl]benzenecarboxylic acid
CAS 400082-02-2C10H8N2O2S2
Isopropyl 5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate chemical structure, C12H11ClN2O2S2, CAS 306976-89-6
Isopropyl 5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate
CAS 306976-89-6C12H11ClN2O2S2
Ethyl 5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylate chemical structure, C12H9F3N2O2S2, CAS 306977-11-7
Ethyl 5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylate
CAS 306977-11-7C12H9F3N2O2S2
Ethyl 5-[(4-bromophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate chemical structure, C11H9BrN2O2S2, CAS 866143-00-2
Ethyl 5-[(4-bromophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate
CAS 866143-00-2C11H9BrN2O2S2
Ethyl 5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate chemical structure, C11H9ClN2O2S2, CAS 338760-67-1
Ethyl 5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate
CAS 338760-67-1C11H9ClN2O2S2
4-Carboxy-5-((4-chlorophenyl)sulfanyl)-1,2,3-thiadiazole chemical structure, C9H5ClN2O2S2, CAS 338760-78-4
4-Carboxy-5-((4-chlorophenyl)sulfanyl)-1,2,3-thiadiazole
CAS 338760-78-4C9H5ClN2O2S2
5-[(4-Chlorophenyl)sulfanyl]-N-methyl-1,2,3-thiadiazole-4-carboxamide chemical structure, C10H8ClN3OS2, CAS 303151-37-3
5-[(4-Chlorophenyl)sulfanyl]-N-methyl-1,2,3-thiadiazole-4-carboxamide
CAS 303151-37-3C10H8ClN3OS2
5-[(4-Chlorophenyl)sulfanyl]-N,N-dimethyl-1,2,3-thiadiazole-4-carboxamide chemical structure, C11H10ClN3OS2, CAS 303151-38-4
5-[(4-Chlorophenyl)sulfanyl]-N,N-dimethyl-1,2,3-thiadiazole-4-carboxamide
CAS 303151-38-4C11H10ClN3OS2
5-[(4-Chlorophenyl)sulfanyl]-N-propyl-1,2,3-thiadiazole-4-carboxamide chemical structure, C12H12ClN3OS2, CAS 303151-50-0
5-[(4-Chlorophenyl)sulfanyl]-N-propyl-1,2,3-thiadiazole-4-carboxamide
CAS 303151-50-0C12H12ClN3OS2
Ethyl 5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate chemical structure, C12H12N2O2S2, CAS 306977-04-8
Ethyl 5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylate
CAS 306977-04-8C12H12N2O2S2
Ethyl 5-[4-(trifluoromethyl)phenylthio]-1,2,3-thiadiazole-4-carboxylate chemical structure, C12H9F3N2O2S2, CAS 338982-06-2
Ethyl 5-[4-(trifluoromethyl)phenylthio]-1,2,3-thiadiazole-4-carboxylate
CAS 338982-06-2C12H9F3N2O2S2
5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid chemical structure, C10H5F3N2O2S2, CAS 338982-07-3
5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid
CAS 338982-07-3C10H5F3N2O2S2
5-[(4-Bromophenyl)sulfanyl]-4-methyl-1,2,3-thiadiazole chemical structure, C9H7BrN2S2, CAS 338978-69-1
5-[(4-Bromophenyl)sulfanyl]-4-methyl-1,2,3-thiadiazole
CAS 338978-69-1C9H7BrN2S2
4-Methyl-5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole chemical structure, C10H10N2S2, CAS 338978-95-3
4-Methyl-5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole
CAS 338978-95-3C10H10N2S2
4-Bromophenyl 1,2,3-thiadiazol-5-yl sulfide chemical structure, C8H5BrN2S2, CAS 338397-18-5
4-Bromophenyl 1,2,3-thiadiazol-5-yl sulfide
CAS 338397-18-5C8H5BrN2S2
4-Methyl-5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole chemical structure, C10H7F3N2S2, CAS 338397-17-4
4-Methyl-5-{[3-(trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole
CAS 338397-17-4C10H7F3N2S2
Methyl 2-[(4-methyl-1,2,3-thiadiazol-5-yl)sulfanyl]benzenecarboxylate chemical structure, C11H10N2O2S2, CAS 338978-70-4
Methyl 2-[(4-methyl-1,2,3-thiadiazol-5-yl)sulfanyl]benzenecarboxylate
CAS 338978-70-4C11H10N2O2S2
4-Fluorophenyl 4-methyl-1,2,3-thiadiazol-5-yl sulfide chemical structure, C9H7FN2S2, CAS 338978-80-6
4-Fluorophenyl 4-methyl-1,2,3-thiadiazol-5-yl sulfide
CAS 338978-80-6C9H7FN2S2
5-[(2,4-Dichlorophenyl)sulfanyl]-4-methyl-1,2,3-thiadiazole chemical structure, C9H6Cl2N2S2, CAS 338978-81-7
5-[(2,4-Dichlorophenyl)sulfanyl]-4-methyl-1,2,3-thiadiazole
CAS 338978-81-7C9H6Cl2N2S2
Methyl 4-[(4-methyl-1,2,3-thiadiazol-5-yl)sulfanyl]phenyl ether chemical structure, C10H10N2OS2, CAS 338978-75-9
Methyl 4-[(4-methyl-1,2,3-thiadiazol-5-yl)sulfanyl]phenyl ether
CAS 338978-75-9C10H10N2OS2