CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 24 atoms

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
17
With full pages
2
Scaffold SMILES

c1ccc(CCNc2ncnc3c2cnn3-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCNc2ncnc3c2cnn3-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

1-(3-Methylphenyl)-N-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C20H19N5, CAS 393784-39-9
1-(3-Methylphenyl)-N-(2-phenylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393784-39-9C20H19N5
4-[2-[[1-(2,4-Dimethylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]ethyl]benzenesulfonamide chemical structure, C21H22N6O2S, CAS 393823-05-7
4-[2-[[1-(2,4-Dimethylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]ethyl]benzenesulfonamide
CAS 393823-05-7C21H22N6O2S
4-(2-{[1-(4-Methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)benzenesulfonamide chemical structure, C20H20N6O3S, CAS 393822-73-6
4-(2-{[1-(4-Methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}ethyl)benzenesulfonamide
CAS 393822-73-6C20H20N6O3S
1-(4-Chlorophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C21H20ClN5O2, CAS 393784-63-9
1-(4-Chlorophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393784-63-9C21H20ClN5O2
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-phenylpyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C21H21N5O2, CAS 300816-49-3
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-phenylpyrazolo[3,4-d]pyrimidin-4-amine
CAS 300816-49-3C21H21N5O2
N-(4-Chlorophenethyl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C20H18ClN5, CAS 393820-56-9
N-(4-Chlorophenethyl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393820-56-9C20H18ClN5
4-[2-[(1-Phenylpyrazolo[3,4-d]pyrimidin-4-yl)amino]ethyl]benzenesulfonamide chemical structure, C19H18N6O2S, CAS 393820-34-3
4-[2-[(1-Phenylpyrazolo[3,4-d]pyrimidin-4-yl)amino]ethyl]benzenesulfonamide
CAS 393820-34-3C19H18N6O2S
4-[2-[[1-(3-Methylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]ethyl]benzenesulfonamide chemical structure, C20H20N6O2S, CAS 393821-21-1
4-[2-[[1-(3-Methylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]ethyl]benzenesulfonamide
CAS 393821-21-1C20H20N6O2S
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(2,4-dimethylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C23H25N5O2, CAS 393784-66-2
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(2,4-dimethylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393784-66-2C23H25N5O2
4-[2-[[1-(2-Chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]ethyl]benzenesulfonamide chemical structure, C19H17ClN6O2S, CAS 852314-14-8
4-[2-[[1-(2-Chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]ethyl]benzenesulfonamide
CAS 852314-14-8C19H17ClN6O2S
[1-(3-Chlorophenyl)pyrazolo[4,5-e]pyrimidin-4-yl](2-phenylethyl)amine chemical structure, C19H16ClN5, CAS 890942-87-7
[1-(3-Chlorophenyl)pyrazolo[4,5-e]pyrimidin-4-yl](2-phenylethyl)amine
CAS 890942-87-7C19H16ClN5
4-(2-((1-(3,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)benzenesulfonamide chemical structure, C21H22N6O2S, CAS 890890-25-2
4-(2-((1-(3,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)benzenesulfonamide
CAS 890890-25-2C21H22N6O2S
4-(2-((1-(3-Chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)benzenesulfonamide chemical structure, C20H19ClN6O2S, CAS 890895-99-5
4-(2-((1-(3-Chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)benzenesulfonamide
CAS 890895-99-5C20H19ClN6O2S
1-(3-Chlorophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C21H20ClN5O2, CAS 890942-99-1
1-(3-Chlorophenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 890942-99-1C21H20ClN5O2
1-(5-Chloro-2-methylphenyl)-N-(3,4-dimethoxyphenethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C22H22ClN5O2, CAS 890937-13-0
1-(5-Chloro-2-methylphenyl)-N-(3,4-dimethoxyphenethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 890937-13-0C22H22ClN5O2
1-(3-Chloro-4-methylphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C22H22ClN5O2, CAS 890890-87-6
1-(3-Chloro-4-methylphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 890890-87-6C22H22ClN5O2
4-(2-((1-(2,5-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)benzenesulfonamide chemical structure, C21H22N6O2S, CAS 1105233-94-0
4-(2-((1-(2,5-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethyl)benzenesulfonamide
CAS 1105233-94-0C21H22N6O2S