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Murcko scaffold

Ring system with 4 rings and 18 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
18
Chemicals
6
With full pages
3
Scaffold SMILES

O=C1OCC2=C1CCC1c3ccccc3CCC21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OCC2=C1CCC1c3ccccc3CCC21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Neotriptophenolide chemical structure, C21H26O4, CAS 81827-74-9
Neotriptophenolide
CAS 81827-74-9C21H26O4
Triptophenolide methyl ether chemical structure, C21H26O3, CAS 74311-48-1
Triptophenolide methyl ether
CAS 74311-48-1C21H26O3
Triptophenolide chemical structure, C20H24O3, CAS 74285-86-2
Triptophenolide
CAS 74285-86-2C20H24O3
(3bR,9bS)-8-Hydroxy-6-methoxy-9b-methyl-7-(propan-2-yl)-3b,4,5,9b,10,11-hexahydrophenanthro[1,2-c]furan-1(3H)-one chemical structure, C21H26O4, CAS 104331-86-4
(3bR,9bS)-8-Hydroxy-6-methoxy-9b-methyl-7-(propan-2-yl)-3b,4,5,9b,10,11-hexahydrophenanthro[1,2-c]furan-1(3H)-one
CAS 104331-86-4C21H26O4
6-Methoxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one chemical structure, C21H26O3, CAS 73414-41-2
6-Methoxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one
CAS 73414-41-2C21H26O3
(3bR,9bS)-6-Methoxy-9b-methyl-3b,4,5,9b,10,11-hexahydrophenanthro[1,2-c]furan-1(3H)-one chemical structure, C18H20O3, CAS 1209485-40-4
(3bR,9bS)-6-Methoxy-9b-methyl-3b,4,5,9b,10,11-hexahydrophenanthro[1,2-c]furan-1(3H)-one
CAS 1209485-40-4C18H20O3