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Murcko scaffold

1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole scaffold

29 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
29
With full pages
3
Scaffold SMILES

c1ccc(-n2nccc2-c2cccs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole page
Murcko scaffold c1ccc(-n2nccc2-c2cccs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

5-(3-Chloro-2-thienyl)-1-phenyl-1H-pyrazole chemical structure, C13H9ClN2S, CAS 321537-94-4
5-(3-Chloro-2-thienyl)-1-phenyl-1H-pyrazole
CAS 321537-94-4C13H9ClN2S
1-(4-Chlorophenyl)-5-(3-chloro-2-thienyl)-1H-pyrazole chemical structure, C13H8Cl2N2S, CAS 477762-25-7
1-(4-Chlorophenyl)-5-(3-chloro-2-thienyl)-1H-pyrazole
CAS 477762-25-7C13H8Cl2N2S
N-(3-Methoxypropyl)-4-[5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzamide chemical structure, C19H18F3N3O2S, CAS 956683-88-8
N-(3-Methoxypropyl)-4-[5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzamide
CAS 956683-88-8C19H18F3N3O2S
1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid chemical structure, C14H10N2O2S, CAS 220192-02-9
1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS 220192-02-9C14H10N2O2S
Methyl 1-(4-carboxyphenyl)-5-thien-2-yl-1H-pyrazole-3-carboxylate chemical structure, C16H12N2O4S, CAS 957320-47-7
Methyl 1-(4-carboxyphenyl)-5-thien-2-yl-1H-pyrazole-3-carboxylate
CAS 957320-47-7C16H12N2O4S
4-[5-(2-Thienyl)-3-(trifluoromethyl)pyrazolyl]benzoic acid chemical structure, C15H9F3N2O2S, CAS 884379-58-2
4-[5-(2-Thienyl)-3-(trifluoromethyl)pyrazolyl]benzoic acid
CAS 884379-58-2C15H9F3N2O2S
Methyl 1-phenyl-5-(2-thienyl)-1H-pyrazole-3-carboxylate chemical structure, C15H12N2O2S, CAS 1003499-15-7
Methyl 1-phenyl-5-(2-thienyl)-1H-pyrazole-3-carboxylate
CAS 1003499-15-7C15H12N2O2S
N-(1-Methoxypropan-2-yl)-4-[5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzamide chemical structure, C19H18F3N3O2S, CAS 956405-51-9
N-(1-Methoxypropan-2-yl)-4-[5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzamide
CAS 956405-51-9C19H18F3N3O2S
1-(3,5-Dichlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid chemical structure, C14H8Cl2N2O2S, CAS 956769-56-5
1-(3,5-Dichlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS 956769-56-5C14H8Cl2N2O2S
1-(4-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid chemical structure, C14H9FN2O2S, CAS 956704-21-5
1-(4-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS 956704-21-5C14H9FN2O2S
1-(2,4-Difluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid chemical structure, C14H8F2N2O2S, CAS 1013980-01-2
1-(2,4-Difluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS 1013980-01-2C14H8F2N2O2S
1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H10N2S, CAS 478395-52-7
1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole
CAS 478395-52-7C13H10N2S
1-(4-Bromophenyl)-5-(2-thienyl)-1H-pyrazole chemical structure, C13H9BrN2S, CAS 478395-54-9
1-(4-Bromophenyl)-5-(2-thienyl)-1H-pyrazole
CAS 478395-54-9C13H9BrN2S
1-(2-Bromophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9BrN2S, CAS 1269292-50-3
1-(2-Bromophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269292-50-3C13H9BrN2S
1-(2-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9FN2S, CAS 1269294-34-9
1-(2-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269294-34-9C13H9FN2S
1-(3-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9FN2S, CAS 1269293-54-0
1-(3-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269293-54-0C13H9FN2S
1-(4-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9FN2S, CAS 1269291-65-7
1-(4-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269291-65-7C13H9FN2S
1-(2-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9ClN2S, CAS 1269291-36-2
1-(2-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269291-36-2C13H9ClN2S
1-(3-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9ClN2S, CAS 1269294-21-4
1-(3-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269294-21-4C13H9ClN2S
1-(4-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9ClN2S, CAS 1269294-00-9
1-(4-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269294-00-9C13H9ClN2S
5-(Thiophen-2-yl)-1-(p-tolyl)-1H-pyrazole chemical structure, C14H12N2S, CAS 1269291-68-0
5-(Thiophen-2-yl)-1-(p-tolyl)-1H-pyrazole
CAS 1269291-68-0C14H12N2S
1-(2-Nitrophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9N3O2S, CAS 1269293-17-5
1-(2-Nitrophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269293-17-5C13H9N3O2S
1-(4-Nitrophenyl)-5-(thiophen-2-yl)-1H-pyrazole chemical structure, C13H9N3O2S, CAS 1269292-53-6
1-(4-Nitrophenyl)-5-(thiophen-2-yl)-1H-pyrazole
CAS 1269292-53-6C13H9N3O2S
[5-(5-Bromothiophen-2-yl)-1-(2-chlorophenyl)-1H-pyrazol-3-yloxy]acetic acid methyl ester chemical structure, C16H12BrClN2O3S, CAS 1033586-52-5
[5-(5-Bromothiophen-2-yl)-1-(2-chlorophenyl)-1H-pyrazol-3-yloxy]acetic acid methyl ester
CAS 1033586-52-5C16H12BrClN2O3S