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Murcko scaffold

Ring system with 2 rings and 18 atoms

195 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
195
With full pages
13
Scaffold SMILES

O=S(=O)(C=CNc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(C=CNc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 195 chemicals

N-[2-Nitro-2-(phenylsulfonyl)vinyl]aniline chemical structure, C14H12N2O4S, CAS 1164530-75-9
N-[2-Nitro-2-(phenylsulfonyl)vinyl]aniline
CAS 1164530-75-9C14H12N2O4S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-4-methylaniline chemical structure, C15H14N2O4S, CAS 321433-80-1
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-4-methylaniline
CAS 321433-80-1C15H14N2O4S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3-chloro-2-methylaniline chemical structure, C15H13ClN2O4S, CAS 321433-85-6
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3-chloro-2-methylaniline
CAS 321433-85-6C15H13ClN2O4S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-4-methoxyaniline chemical structure, C15H14N2O5S, CAS 321433-88-9
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-4-methoxyaniline
CAS 321433-88-9C15H14N2O5S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-2,3-dimethylaniline chemical structure, C16H16N2O4S, CAS 321433-90-3
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-2,3-dimethylaniline
CAS 321433-90-3C16H16N2O4S
3-Methyl-N-[2-nitro-2-(phenylsulfonyl)vinyl]aniline chemical structure, C15H14N2O4S, CAS 321434-04-2
3-Methyl-N-[2-nitro-2-(phenylsulfonyl)vinyl]aniline
CAS 321434-04-2C15H14N2O4S
Methyl 3-{[2-nitro-2-(phenylsulfonyl)vinyl]amino}benzenecarboxylate chemical structure, C16H14N2O6S, CAS 477864-69-0
Methyl 3-{[2-nitro-2-(phenylsulfonyl)vinyl]amino}benzenecarboxylate
CAS 477864-69-0C16H14N2O6S
(E)-2-(4-Chlorophenyl)sulfonyl-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile chemical structure, C16H10ClF3N2O2S, CAS 882255-86-9
(E)-2-(4-Chlorophenyl)sulfonyl-3-[3-(trifluoromethyl)anilino]prop-2-enenitrile
CAS 882255-86-9C16H10ClF3N2O2S
(Z)-3-Anilino-2-(4-methylphenyl)sulfonyl-3-methylsulfanylprop-2-enenitrile chemical structure, C17H16N2O2S2, CAS 151991-27-4
(Z)-3-Anilino-2-(4-methylphenyl)sulfonyl-3-methylsulfanylprop-2-enenitrile
CAS 151991-27-4C17H16N2O2S2
(E)-2-(Benzenesulfonyl)-3-(4-methylanilino)prop-2-enenitrile chemical structure, C16H14N2O2S, CAS 669752-27-6
(E)-2-(Benzenesulfonyl)-3-(4-methylanilino)prop-2-enenitrile
CAS 669752-27-6C16H14N2O2S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3-chloroaniline chemical structure, C14H11ClN2O4S, CAS 338407-51-5
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3-chloroaniline
CAS 338407-51-5C14H11ClN2O4S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-2-chloroaniline chemical structure, C14H11ClN2O4S, CAS 1164476-20-3
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-2-chloroaniline
CAS 1164476-20-3C14H11ClN2O4S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-4-fluoroaniline chemical structure, C14H11FN2O4S, CAS 321433-82-3
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-4-fluoroaniline
CAS 321433-82-3C14H11FN2O4S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3-(trifluoromethyl)aniline chemical structure, C15H11F3N2O4S, CAS 321433-84-5
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3-(trifluoromethyl)aniline
CAS 321433-84-5C15H11F3N2O4S
4-Bromo-N-[2-nitro-2-(phenylsulfonyl)vinyl]aniline chemical structure, C14H11BrN2O4S, CAS 321433-86-7
4-Bromo-N-[2-nitro-2-(phenylsulfonyl)vinyl]aniline
CAS 321433-86-7C14H11BrN2O4S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-2,4-difluoroaniline chemical structure, C14H10F2N2O4S, CAS 321434-00-8
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-2,4-difluoroaniline
CAS 321434-00-8C14H10F2N2O4S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3,4-dichloroaniline chemical structure, C14H10Cl2N2O4S, CAS 321434-02-0
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-3,4-dichloroaniline
CAS 321434-02-0C14H10Cl2N2O4S
(E)-3-(2,5-Dimethylanilino)-2-(4-methylphenyl)sulfonylprop-2-enenitrile chemical structure, C18H18N2O2S, CAS 1025640-63-4
(E)-3-(2,5-Dimethylanilino)-2-(4-methylphenyl)sulfonylprop-2-enenitrile
CAS 1025640-63-4C18H18N2O2S
4-Fluoro-N-[(E)-2-(4-methylphenyl)sulfonyl-2-nitroethenyl]aniline chemical structure, C15H13FN2O4S, CAS 1024790-72-4
4-Fluoro-N-[(E)-2-(4-methylphenyl)sulfonyl-2-nitroethenyl]aniline
CAS 1024790-72-4C15H13FN2O4S
Methyl 5-(4-methoxyanilino)-4-(phenylsulfonyl)-2,4-pentadienoate chemical structure, C19H19NO5S, CAS 339276-70-9
Methyl 5-(4-methoxyanilino)-4-(phenylsulfonyl)-2,4-pentadienoate
CAS 339276-70-9C19H19NO5S
N-[(E)-2-(4-Chlorophenyl)sulfonyl-2-nitroethenyl]-3,5-bis(trifluoromethyl)aniline chemical structure, C16H9ClF6N2O4S, CAS 1025527-59-6
N-[(E)-2-(4-Chlorophenyl)sulfonyl-2-nitroethenyl]-3,5-bis(trifluoromethyl)aniline
CAS 1025527-59-6C16H9ClF6N2O4S
Ethyl 3-((4-ethoxyphenyl)amino)-2-((4-methylphenyl)sulfonyl)prop-2-enoate chemical structure, C20H23NO5S, CAS 1024742-76-4
Ethyl 3-((4-ethoxyphenyl)amino)-2-((4-methylphenyl)sulfonyl)prop-2-enoate
CAS 1024742-76-4C20H23NO5S
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-4-chloroaniline chemical structure, C14H11ClN2O4S, CAS 338397-49-2
N-[(E)-2-(Benzenesulfonyl)-2-nitroethenyl]-4-chloroaniline
CAS 338397-49-2C14H11ClN2O4S
(Z)-2-(Benzenesulfonyl)-3-(3-chloroanilino)-3-methylsulfanylprop-2-enenitrile chemical structure, C16H13ClN2O2S2, CAS 1025268-52-3
(Z)-2-(Benzenesulfonyl)-3-(3-chloroanilino)-3-methylsulfanylprop-2-enenitrile
CAS 1025268-52-3C16H13ClN2O2S2