Murcko scaffold
1-Phenyl-5H-2,3-benzodiazepine scaffold
10 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 17
- Chemicals
- 10
- With full pages
- 5
Scaffold SMILES
C1=NN=C(c2ccccc2)c2ccccc2C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
Tofisopam
CAS 22345-47-7C22H26N2O4
Nerisopam
CAS 102771-12-0C18H19N3O2
Girisopam
CAS 82230-53-3C18H17ClN2O2
Egis 7649
CAS 177034-98-9C20H21N3O3
Dextofisopam
CAS 82059-50-5C22H26N2O4
1-Phenyl-5H-2,3-benzodiazepine
CAS 52095-33-7C15H12N2
5H-2,3-Benzodiazepine-4-methanol, 1-(3-chlorophenyl)-7,8-dimethoxy-
CAS 142790-94-1C18H17ClN2O3
Levotofisopam
CAS 82059-51-6C22H26N2O4
1-(4-Fluorophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
CAS 88145-29-3C18H17FN2O2
8-Chloro-4-methyl-1-(3-methyl-4-nitrophenyl)-5H-2,3-benzodiazepine
CAS 840526-71-8C17H14ClN3O2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C1CN=C(c2ccccc2)c2ccccc2N1113 chemicals
c1ccc(C2CNCCc3ccccc32)cc148 chemicals
O=C1CNC(c2ccccc2)c2ccccc2N18 chemicals
C1=Nc2ccccc2C(c2ccccc2)=NC16 chemicals
S=C1CN=C(c2ccccc2)c2ccccc2N15 chemicals
O=C1CC(=O)N(c2ccccc2)c2ccccc2N14 chemicals
N=C1CNC(c2ccccc2)=c2ccccc2=N14 chemicals
O=C1CN=C(c2ccccn2)c2ccccc2N14 chemicals
O=C1CNC(c2ccccc2)=c2ccccc2=N13 chemicals
c1ccc(C2=NCCNc3ccccc32)cc13 chemicals
O=S1(=O)CCNC(c2ccccc2)c2ccccc213 chemicals
O=C1Cc2ccccc2C(c2ccccc2)=NN12 chemicals