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Murcko scaffold

1-Cyclobutylpiperazine scaffold

154 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
154
With full pages
11
Scaffold SMILES

C1CC(N2CCNCC2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Cyclobutylpiperazine page
Murcko scaffold C1CC(N2CCNCC2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 154 chemicals

1-Cyclobutylpiperazine chemical structure, C8H16N2, CAS 132800-13-6
1-Cyclobutylpiperazine
CAS 132800-13-6C8H16N2
4-Cyclobutylpiperazin-1-amine chemical structure, C8H17N3, CAS 61379-68-8
4-Cyclobutylpiperazin-1-amine
CAS 61379-68-8C8H17N3
1-Cyclobutylpiperazine hydrochloride chemical structure, C8H17ClN2, CAS 741287-54-7
1-Cyclobutylpiperazine hydrochloride
CAS 741287-54-7C8H17ClN2
1-Cyclobutyl-4-nitrosopiperazine chemical structure, C8H15N3O, CAS 61379-69-9
1-Cyclobutyl-4-nitrosopiperazine
CAS 61379-69-9C8H15N3O
1-Cyclobutyl-2-methylpiperazine chemical structure, C9H18N2, CAS 949922-66-1
1-Cyclobutyl-2-methylpiperazine
CAS 949922-66-1C9H18N2
1-Cyclobutylpiperazine dihydrochloride chemical structure, C8H18Cl2N2, CAS 799557-65-6
1-Cyclobutylpiperazine dihydrochloride
CAS 799557-65-6C8H18Cl2N2
1-(Chloroacetyl)-4-cyclobutylpiperazine chemical structure, C10H17ClN2O, CAS 923945-27-1
1-(Chloroacetyl)-4-cyclobutylpiperazine
CAS 923945-27-1C10H17ClN2O
tert-Butyl 4-cyclobutylpiperazine-1-carboxylate chemical structure, C13H24N2O2, CAS 485798-62-7
tert-Butyl 4-cyclobutylpiperazine-1-carboxylate
CAS 485798-62-7C13H24N2O2
3-(4-Methyl-1-piperazinyl)cyclobutanamine chemical structure, C9H19N3, CAS 1213250-15-7
3-(4-Methyl-1-piperazinyl)cyclobutanamine
CAS 1213250-15-7C9H19N3
3-(Piperazin-1-yl)cyclobutan-1-ol chemical structure, C8H16N2O, CAS 2258649-65-7
3-(Piperazin-1-yl)cyclobutan-1-ol
CAS 2258649-65-7C8H16N2O
1-Boc-4-(trans-3-hydroxycyclobutyl)piperazine chemical structure, C13H24N2O3, CAS 2258649-63-5
1-Boc-4-(trans-3-hydroxycyclobutyl)piperazine
CAS 2258649-63-5C13H24N2O3
(R)-1-Cyclobutyl-3-methylpiperazine chemical structure, C9H18N2, CAS 1240914-73-1
(R)-1-Cyclobutyl-3-methylpiperazine
CAS 1240914-73-1C9H18N2
(s)-1-Cyclobutyl-2-methylpiperazine chemical structure, C9H18N2, CAS 1227664-50-7
(s)-1-Cyclobutyl-2-methylpiperazine
CAS 1227664-50-7C9H18N2
tert-Butyl (3S)-4-cyclobutyl-3-methylpiperazine-1-carboxylate chemical structure, C14H26N2O2, CAS 1240914-37-7
tert-Butyl (3S)-4-cyclobutyl-3-methylpiperazine-1-carboxylate
CAS 1240914-37-7C14H26N2O2
(2R)-1-Cyclobutyl-2-methylpiperazine chemical structure, C9H18N2, CAS 1241093-83-3
(2R)-1-Cyclobutyl-2-methylpiperazine
CAS 1241093-83-3C9H18N2
1-(Piperazin-1-yl)cyclobutane-1-carboxamide chemical structure, C9H17N3O, CAS 1178286-86-6
1-(Piperazin-1-yl)cyclobutane-1-carboxamide
CAS 1178286-86-6C9H17N3O
1-(Piperazin-1-yl)cyclobutane-1-carboxylic acid chemical structure, C9H16N2O2, CAS 1249895-47-3
1-(Piperazin-1-yl)cyclobutane-1-carboxylic acid
CAS 1249895-47-3C9H16N2O2
Methyl 1-(piperazin-1-yl)cyclobutane-1-carboxylate chemical structure, C10H18N2O2, CAS 1249026-99-0
Methyl 1-(piperazin-1-yl)cyclobutane-1-carboxylate
CAS 1249026-99-0C10H18N2O2
Ethyl 1-(piperazin-1-yl)cyclobutane-1-carboxylate chemical structure, C11H20N2O2, CAS 1249468-80-1
Ethyl 1-(piperazin-1-yl)cyclobutane-1-carboxylate
CAS 1249468-80-1C11H20N2O2
1-Cyclobutyl-2-ethylpiperazine chemical structure, C10H20N2, CAS 1497014-46-6
1-Cyclobutyl-2-ethylpiperazine
CAS 1497014-46-6C10H20N2
1-Cyclobutyl-2-(propan-2-yl)piperazine chemical structure, C11H22N2, CAS 1467123-60-9
1-Cyclobutyl-2-(propan-2-yl)piperazine
CAS 1467123-60-9C11H22N2
1-(4-(3-Aminocyclobutyl)piperazin-1-yl)ethan-1-one chemical structure, C10H19N3O, CAS 1272668-29-7
1-(4-(3-Aminocyclobutyl)piperazin-1-yl)ethan-1-one
CAS 1272668-29-7C10H19N3O
[3-(4-Acetylpiperazin-1-yl)cyclobutyl]carbamic acid tert-butyl ester chemical structure, C15H27N3O3, CAS 1272668-30-0
[3-(4-Acetylpiperazin-1-yl)cyclobutyl]carbamic acid tert-butyl ester
CAS 1272668-30-0C15H27N3O3
(R)-1-Cyclobutyl-3-methylpiperazine dihydrochloride chemical structure, C9H20Cl2N2, CAS 1327162-37-7
(R)-1-Cyclobutyl-3-methylpiperazine dihydrochloride
CAS 1327162-37-7C9H20Cl2N2