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Murcko scaffold

2-(Pyridin-3-yl)-1,3,4-oxadiazole scaffold

63 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
63
With full pages
5
Scaffold SMILES

c1cncc(-c2nnco2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyridin-3-yl)-1,3,4-oxadiazole page
Murcko scaffold c1cncc(-c2nnco2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 63 of 63 chemicals

2-[4-(Trifluoromethyl)pyridin-3-yl]-1,3,4-oxadiazole chemical structure, C8H4F3N3O, CAS 2688920-09-2
2-[4-(Trifluoromethyl)pyridin-3-yl]-1,3,4-oxadiazole
CAS 2688920-09-2C8H4F3N3O
2-(2-Methoxy-3-pyridyl)-1,3,4-oxadiazole chemical structure, C8H7N3O2, CAS 2683213-91-2
2-(2-Methoxy-3-pyridyl)-1,3,4-oxadiazole
CAS 2683213-91-2C8H7N3O2
3-Bromo-5-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]pyridine chemical structure, C8H3BrCl3N3O, CAS 2361645-10-3
3-Bromo-5-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]pyridine
CAS 2361645-10-3C8H3BrCl3N3O
2-(5,6-Dichloro-3-pyridinyl)-5-methyl-1,3,4-oxadiazole chemical structure, C8H5Cl2N3O, CAS 1412944-99-0
2-(5,6-Dichloro-3-pyridinyl)-5-methyl-1,3,4-oxadiazole
CAS 1412944-99-0C8H5Cl2N3O
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]pyridin-2-amine chemical structure, C8H6F2N4O, CAS 2444301-65-7
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]pyridin-2-amine
CAS 2444301-65-7C8H6F2N4O
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-fluoropyridine chemical structure, C8H4F3N3O, CAS 2137870-57-4
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-fluoropyridine
CAS 2137870-57-4C8H4F3N3O
2-(Difluoromethyl)-5-(5-fluoro-6-methylpyridin-3-yl)-1,3,4-oxadiazole chemical structure, C9H6F3N3O, CAS 2832528-89-7
2-(Difluoromethyl)-5-(5-fluoro-6-methylpyridin-3-yl)-1,3,4-oxadiazole
CAS 2832528-89-7C9H6F3N3O
5-(5-Methyl-1,3,4-oxadiazol-2-yl)pyridine-3-carbaldehyde chemical structure, C9H7N3O2, CAS 2137767-44-1
5-(5-Methyl-1,3,4-oxadiazol-2-yl)pyridine-3-carbaldehyde
CAS 2137767-44-1C9H7N3O2
5-[5-(Propan-2-yl)-1,3,4-oxadiazol-2-yl]pyridine-3-carbaldehyde chemical structure, C11H11N3O2, CAS 2137579-77-0
5-[5-(Propan-2-yl)-1,3,4-oxadiazol-2-yl]pyridine-3-carbaldehyde
CAS 2137579-77-0C11H11N3O2
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]pyridine-3-carbaldehyde chemical structure, C9H5F2N3O2, CAS 2137767-45-2
5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]pyridine-3-carbaldehyde
CAS 2137767-45-2C9H5F2N3O2
2-Fluoro-5-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]pyridine chemical structure, C10H10FN3O, CAS 2137761-67-0
2-Fluoro-5-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]pyridine
CAS 2137761-67-0C10H10FN3O
5-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)-2-fluoropyridine chemical structure, C11H12FN3O, CAS 2137761-60-3
5-(5-tert-Butyl-1,3,4-oxadiazol-2-yl)-2-fluoropyridine
CAS 2137761-60-3C11H12FN3O
tert-Butyl N-[5-(5-bromopyridin-3-yl)-1,3,4-oxadiazol-2-yl]carbamate chemical structure, C12H13BrN4O3, CAS 2680742-69-0
tert-Butyl N-[5-(5-bromopyridin-3-yl)-1,3,4-oxadiazol-2-yl]carbamate
CAS 2680742-69-0C12H13BrN4O3
[5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridyl]methanol chemical structure, C9H7F2N3O2, CAS 3115504-93-0
[5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridyl]methanol
CAS 3115504-93-0C9H7F2N3O2
2-(6-Bromopyridin-3-yl)-5-(difluoromethyl)-1,3,4-oxadiazole chemical structure, C8H4BrF2N3O, CAS 2706438-47-1
2-(6-Bromopyridin-3-yl)-5-(difluoromethyl)-1,3,4-oxadiazole
CAS 2706438-47-1C8H4BrF2N3O