CompoundList
Sign in
Murcko scaffold

2-Benzyl-1,3(2H,4H)-isoquinolinedione scaffold

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
9
With full pages
4
Scaffold SMILES

O=C1Cc2ccccc2C(=O)N1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzyl-1,3(2H,4H)-isoquinolinedione page
Murcko scaffold O=C1Cc2ccccc2C(=O)N1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-Benzyl-1,3(2H,4H)-isoquinolinedione chemical structure, C16H13NO2, CAS 21640-31-3
2-Benzyl-1,3(2H,4H)-isoquinolinedione
CAS 21640-31-3C16H13NO2
2-(4-Methoxy-benzyl)-4H-isoquinoline-1,3-dione chemical structure, C17H15NO3, CAS 217493-71-5
2-(4-Methoxy-benzyl)-4H-isoquinoline-1,3-dione
CAS 217493-71-5C17H15NO3
2-(3-Chlorobenzyl)-1,3(2H,4H)-isoquinolinedione chemical structure, C16H12ClNO2, CAS 341965-94-4
2-(3-Chlorobenzyl)-1,3(2H,4H)-isoquinolinedione
CAS 341965-94-4C16H12ClNO2
2-Benzyl-7-methoxy-4,4-dimethylisoquinoline-1,3-dione chemical structure, C19H19NO3, CAS 300698-34-4
2-Benzyl-7-methoxy-4,4-dimethylisoquinoline-1,3-dione
CAS 300698-34-4C19H19NO3
1,3(2H,4H)-Isoquinolinedione, 4-(1-methylethyl)-2-(phenylmethyl)- chemical structure, C19H19NO2, CAS 190579-12-5
1,3(2H,4H)-Isoquinolinedione, 4-(1-methylethyl)-2-(phenylmethyl)-
CAS 190579-12-5C19H19NO2
2-(4-Methoxybenzyl)-4,4-dimethyl-4H-isoquinoline-1,3-dione chemical structure, C19H19NO3, CAS 217493-72-6
2-(4-Methoxybenzyl)-4,4-dimethyl-4H-isoquinoline-1,3-dione
CAS 217493-72-6C19H19NO3
2-Benzyl-6-nitro-4H-isoquinoline-1,3-dione chemical structure, C16H12N2O4, CAS 208589-94-0
2-Benzyl-6-nitro-4H-isoquinoline-1,3-dione
CAS 208589-94-0C16H12N2O4
2-[(3-Amino-4-chlorophenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione chemical structure, C16H13ClN2O2, CAS 1097826-29-3
2-[(3-Amino-4-chlorophenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione
CAS 1097826-29-3C16H13ClN2O2
7-Amino-2-benzylisoquinoline-1,3(2H,4H)-dione chemical structure, C16H14N2O2, CAS 1782556-06-2
7-Amino-2-benzylisoquinoline-1,3(2H,4H)-dione
CAS 1782556-06-2C16H14N2O2