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Murcko scaffold

Ring system with 2 rings and 18 atoms

131 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
131
With full pages
31
Scaffold SMILES

O=C(C=Cc1ccccc1)C=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)C=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 131 chemicals

1,5-Bis(4-methoxyphenyl)-1,4-pentadien-3-one chemical structure, C19H18O3, CAS 2051-07-2
1,5-Bis(4-methoxyphenyl)-1,4-pentadien-3-one
CAS 2051-07-2C19H18O3
1,4-Pentadien-3-one, 1,5-bis[4-(diethylamino)phenyl]- chemical structure, C25H32N2O, CAS 61445-93-0
1,4-Pentadien-3-one, 1,5-bis[4-(diethylamino)phenyl]-
CAS 61445-93-0C25H32N2O
1,5-Diphenylpenta-1,4-dien-3-one, palladium chemical structure, C34H28O2Pd, CAS 32005-36-0
1,5-Diphenylpenta-1,4-dien-3-one, palladium
CAS 32005-36-0C34H28O2Pd
1,5-Bis(2-chlorophenyl)-1,4-pentadien-3-one chemical structure, C17H12Cl2O, CAS 5332-98-9
1,5-Bis(2-chlorophenyl)-1,4-pentadien-3-one
CAS 5332-98-9C17H12Cl2O
1,5-Bis(5-bromo-2-hydroxyphenyl)penta-1,4-dien-3-one chemical structure, C17H12Br2O3, CAS 6291-00-5
1,5-Bis(5-bromo-2-hydroxyphenyl)penta-1,4-dien-3-one
CAS 6291-00-5C17H12Br2O3
1,5-Bis(3-hydroxyphenyl)-1,4-pentadiene-3-one chemical structure, C17H14O3
1,5-Bis(3-hydroxyphenyl)-1,4-pentadiene-3-one
C17H14O3
1,5-Bis(3,4,5-trimethoxyphenyl)penta-1,4-dien-3-one chemical structure, C23H26O7, CAS 17537-28-9
1,5-Bis(3,4,5-trimethoxyphenyl)penta-1,4-dien-3-one
CAS 17537-28-9C23H26O7
1,5-Bis(3,4-dimethoxyphenyl)-1,4-pentadien-3-one chemical structure, C21H22O5, CAS 38552-39-5
1,5-Bis(3,4-dimethoxyphenyl)-1,4-pentadien-3-one
CAS 38552-39-5C21H22O5
1,5-Bis(4-trifluoromethylphenyl)-penta-1,4-diene-3-one chemical structure, C19H12F6O, CAS 42160-07-6
1,5-Bis(4-trifluoromethylphenyl)-penta-1,4-diene-3-one
CAS 42160-07-6C19H12F6O
(1E,4E)-1,5-Diphenyl-1,4-pentadien-3-one chemical structure, C17H14O, CAS 35225-79-7
(1E,4E)-1,5-Diphenyl-1,4-pentadien-3-one
CAS 35225-79-7C17H14O
Bis(4-methoxybenzylidene)acetone chemical structure, C19H18O3, CAS 37951-12-5
Bis(4-methoxybenzylidene)acetone
CAS 37951-12-5C19H18O3
1,4-Pentadien-3-one, 1-(4-methoxyphenyl)-5-phenyl-, (E,E)- chemical structure, C18H16O2, CAS 115846-97-4
1,4-Pentadien-3-one, 1-(4-methoxyphenyl)-5-phenyl-, (E,E)-
CAS 115846-97-4C18H16O2
trans,trans-Bis[4-(dimethylamino)benzylidene]acetone chemical structure, C21H24N2O, CAS 98303-49-2
trans,trans-Bis[4-(dimethylamino)benzylidene]acetone
CAS 98303-49-2C21H24N2O
(1E,4E)-1,5-Bis(2-methoxyphenyl)penta-1,4-dien-3-one chemical structure, C19H18O3, CAS 39777-61-2
(1E,4E)-1,5-Bis(2-methoxyphenyl)penta-1,4-dien-3-one
CAS 39777-61-2C19H18O3
TrxR1-IN-B19 chemical structure, C21H22O5, CAS 170950-29-5
TrxR1-IN-B19
CAS 170950-29-5C21H22O5
1,5-Bis(4-fluorophenyl)-1,4-pentadien-3-one chemical structure, C17H12F2O, CAS 33386-21-9
1,5-Bis(4-fluorophenyl)-1,4-pentadien-3-one
CAS 33386-21-9C17H12F2O
(1E,4E)-1,5-Bis(4-fluorophenyl)penta-1,4-dien-3-one chemical structure, C17H12F2O, CAS 53369-00-9
(1E,4E)-1,5-Bis(4-fluorophenyl)penta-1,4-dien-3-one
CAS 53369-00-9C17H12F2O
(1E,4E)-1,5-Bis(2,4-dimethoxyphenyl)penta-1,4-dien-3-one chemical structure, C21H22O5, CAS 143287-23-4
(1E,4E)-1,5-Bis(2,4-dimethoxyphenyl)penta-1,4-dien-3-one
CAS 143287-23-4C21H22O5
Dibenzalacetone, (1Z,4Z)- chemical structure, C17H14O, CAS 58321-78-1
Dibenzalacetone, (1Z,4Z)-
CAS 58321-78-1C17H14O
Dibenzalacetone, (1Z,4E)- chemical structure, C17H14O, CAS 115587-57-0
Dibenzalacetone, (1Z,4E)-
CAS 115587-57-0C17H14O
(1E,4E)-1,5-Bis(3,4,5-trimethoxyphenyl)penta-1,4-dien-3-one chemical structure, C23H26O7, CAS 209051-29-6
(1E,4E)-1,5-Bis(3,4,5-trimethoxyphenyl)penta-1,4-dien-3-one
CAS 209051-29-6C23H26O7
(1E,4E)-1,5-Bis(3-methoxyphenyl)penta-1,4-dien-3-one chemical structure, C19H18O3, CAS 458533-66-9
(1E,4E)-1,5-Bis(3-methoxyphenyl)penta-1,4-dien-3-one
CAS 458533-66-9C19H18O3
(1E,4E)-1,5-Bis(2-fluorophenyl)penta-1,4-dien-3-one chemical structure, C17H12F2O, CAS 914295-38-8
(1E,4E)-1,5-Bis(2-fluorophenyl)penta-1,4-dien-3-one
CAS 914295-38-8C17H12F2O
1,4-Pentadien-3-one, 1,5-bis(3-chlorophenyl)- chemical structure, C17H12Cl2O, CAS 119869-71-5
1,4-Pentadien-3-one, 1,5-bis(3-chlorophenyl)-
CAS 119869-71-5C17H12Cl2O