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Murcko scaffold

Ring system with 2 rings and 18 atoms

131 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
131
With full pages
31
Scaffold SMILES

O=C(C=Cc1ccccc1)C=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)C=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 131 chemicals

1,5-Bis(4-hydroxyphenyl)penta-1,4-dien-3-one chemical structure, C17H14O3, CAS 3654-49-7
1,5-Bis(4-hydroxyphenyl)penta-1,4-dien-3-one
CAS 3654-49-7C17H14O3
1,5-Bis(4-azidophenyl)-1,4-pentadien-3-one chemical structure, C17H12N6O, CAS 5284-80-0
1,5-Bis(4-azidophenyl)-1,4-pentadien-3-one
CAS 5284-80-0C17H12N6O
(1Z,4E)-1-Hydroxy-1,5-diphenyl-1,4-pentadien-3-one chemical structure, C34H26CuO4, CAS 6290-84-2
(1Z,4E)-1-Hydroxy-1,5-diphenyl-1,4-pentadien-3-one
CAS 6290-84-2C34H26CuO4
1,5-Bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one chemical structure, C19H18O5, CAS 131359-25-6
1,5-Bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one
CAS 131359-25-6C19H18O5
(1E,4E)-1,5-Diphenylpenta-1,4-dien-3-one, palladium chemical structure, C34H28O2Pd, CAS 52409-22-0
(1E,4E)-1,5-Diphenylpenta-1,4-dien-3-one, palladium
CAS 52409-22-0C34H28O2Pd
(4E)-1-Hydroxy-1-(2-hydroxyphenyl)-5-phenylpenta-1,4-dien-3-one chemical structure, C17H14O3, CAS 205308-02-7
(4E)-1-Hydroxy-1-(2-hydroxyphenyl)-5-phenylpenta-1,4-dien-3-one
CAS 205308-02-7C17H14O3
1-(3-Methoxyphenyl)-5-(3-methylphenyl)penta-1,4-dien-3-one chemical structure, C19H18O2, CAS 1030212-75-9
1-(3-Methoxyphenyl)-5-(3-methylphenyl)penta-1,4-dien-3-one
CAS 1030212-75-9C19H18O2
Bis(dibenzylideneacetone)palladium chemical structure, C51H42O3Pd2, CAS 51364-51-3
Bis(dibenzylideneacetone)palladium
CAS 51364-51-3C51H42O3Pd2
Tris(dibenzylideneacetone)diplatinum(0) chemical structure, C51H42O3Pt2, CAS 63782-74-1
Tris(dibenzylideneacetone)diplatinum(0)
CAS 63782-74-1C51H42O3Pt2
(1E,4E)-1-(4-Hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)-1,4-pentadien-3-one chemical structure, C18H16O4, CAS 148625-88-1
(1E,4E)-1-(4-Hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl)-1,4-pentadien-3-one
CAS 148625-88-1C18H16O4
Pt2(dba)3 chemical structure, C51H42O3Pt2, CAS 35915-79-8
Pt2(dba)3
CAS 35915-79-8C51H42O3Pt2
Palladium, tris[mu-[(1,2-eta:4,5-eta)-(1E,4E)-1,5-diphenyl-1,4-pentadien-3-one]]di-, compd. with trichloromethane (1:1) chemical structure, C52H43Cl3O3Pd2, CAS 52522-40-4
Palladium, tris[mu-[(1,2-eta:4,5-eta)-(1E,4E)-1,5-diphenyl-1,4-pentadien-3-one]]di-, compd. with trichloromethane (1:1)
CAS 52522-40-4C52H43Cl3O3Pd2
Bis(dibenzylideneacetone)platinum chemical structure, C34H28O2Pt
Bis(dibenzylideneacetone)platinum
C34H28O2Pt
(1E,4E)-1,5-Bis[3,5-bis(methoxymethoxy)phenyl]penta-1,4-dien-3-one chemical structure, C25H30O9, CAS 917813-62-8
(1E,4E)-1,5-Bis[3,5-bis(methoxymethoxy)phenyl]penta-1,4-dien-3-one
CAS 917813-62-8C25H30O9
Pd2(dba)3-dba chemical structure, C68H56O4Pd2, CAS 873684-64-1
Pd2(dba)3-dba
CAS 873684-64-1C68H56O4Pd2
(1E,4E)-1-(4-Nitrophenyl)-5-phenylpenta-1,4-dien-3-one chemical structure, C17H13NO3, CAS 68386-88-9
(1E,4E)-1-(4-Nitrophenyl)-5-phenylpenta-1,4-dien-3-one
CAS 68386-88-9C17H13NO3
(1E,4E)-1-(4-Bromophenyl)-5-phenylpenta-1,4-dien-3-one chemical structure, C17H13BrO, CAS 1400279-62-0
(1E,4E)-1-(4-Bromophenyl)-5-phenylpenta-1,4-dien-3-one
CAS 1400279-62-0C17H13BrO
(1E,4E)-1,5-Bis(4-azido-2,3,5,6-tetrafluorophenyl)penta-1,4-dien-3-one chemical structure, C17H4F8N6O, CAS 120384-14-7
(1E,4E)-1,5-Bis(4-azido-2,3,5,6-tetrafluorophenyl)penta-1,4-dien-3-one
CAS 120384-14-7C17H4F8N6O
Dimethyl 4,4'-((1E,4E)-3-oxopenta-1,4-diene-1,5-diyl)dibenzoate chemical structure, C21H18O5, CAS 881916-00-3
Dimethyl 4,4'-((1E,4E)-3-oxopenta-1,4-diene-1,5-diyl)dibenzoate
CAS 881916-00-3C21H18O5
(1E,4E)-1,5-Bis[3,5-dimethoxy-4-(2-propyn-1-yloxy)phenyl]-1,4-pentadien-3-one chemical structure, C27H26O7, CAS 917813-63-9
(1E,4E)-1,5-Bis[3,5-dimethoxy-4-(2-propyn-1-yloxy)phenyl]-1,4-pentadien-3-one
CAS 917813-63-9C27H26O7
Bis(3,5,3 inverted exclamation marka,5 inverted exclamation marka-dimethoxydibenzylideneacetone)palladium(0) chemical structure, C42H44O10Pd, CAS 811862-77-8
Bis(3,5,3 inverted exclamation marka,5 inverted exclamation marka-dimethoxydibenzylideneacetone)palladium(0)
CAS 811862-77-8C42H44O10Pd
E,E-1-(p-Isopropylphenyl)-5-phenyl-1,4-pentadien-3-one chemical structure, C20H20O, CAS 174493-20-0
E,E-1-(p-Isopropylphenyl)-5-phenyl-1,4-pentadien-3-one
CAS 174493-20-0C20H20O
(1Z)-2,4-Dibromo-1,5-diphenyl-1,4-pentadien-3-one chemical structure, C17H12Br2O, CAS 51110-61-3
(1Z)-2,4-Dibromo-1,5-diphenyl-1,4-pentadien-3-one
CAS 51110-61-3C17H12Br2O
(1E,4E)-1,5-Bis(3-fluorophenyl)penta-1,4-dien-3-one chemical structure, C17H12F2O, CAS 881915-98-6
(1E,4E)-1,5-Bis(3-fluorophenyl)penta-1,4-dien-3-one
CAS 881915-98-6C17H12F2O