CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 14 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
20
With full pages
4
Scaffold SMILES

c1cc2[nH]c(-c3cnon3)nc2cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2[nH]c(-c3cnon3)nc2cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

4-(7-Bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C10H8BrClN6O, CAS 842144-07-4
4-(7-Bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
CAS 842144-07-4C10H8BrClN6O
4-(1-Methyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C9H8N6O, CAS 607368-95-6
4-(1-Methyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine
CAS 607368-95-6C9H8N6O
4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C10H10N6O, CAS 607368-87-6
4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
CAS 607368-87-6C10H10N6O
3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]prop-2-yn-1-ol chemical structure, C16H19N7O3, CAS 842148-40-7
3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]prop-2-yn-1-ol
CAS 842148-40-7C16H19N7O3
4-(4-(3-Aminoprop-1-yn-1-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C16H20N8O2, CAS 842148-42-9
4-(4-(3-Aminoprop-1-yn-1-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
CAS 842148-42-9C16H20N8O2
2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-, (2,2,2-trifluoroacetate) (1:2) chemical structure, C20H21F6N7O7, CAS 1052112-65-8
2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-, (2,2,2-trifluoroacetate) (1:2)
CAS 1052112-65-8C20H21F6N7O7
4-(7-Bromo-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C10H9BrN6O, CAS 607370-99-0
4-(7-Bromo-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
CAS 607370-99-0C10H9BrN6O
tert-Butyl 3-(2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yloxy)propylcarbamate chemical structure, C18H24ClN7O4, CAS 1052112-24-9
tert-Butyl 3-(2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yloxy)propylcarbamate
CAS 1052112-24-9C18H24ClN7O4
2-(4-Amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-ol chemical structure, C10H9ClN6O2, CAS 842149-46-6
2-(4-Amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-ol
CAS 842149-46-6C10H9ClN6O2
[4-(7-Bromo-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan-3-yl]-carbamic Acid Tert-Butyl Ester chemical structure, C15H17BrN6O3, CAS 607373-60-4
[4-(7-Bromo-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan-3-yl]-carbamic Acid Tert-Butyl Ester
CAS 607373-60-4C15H17BrN6O3
1H-Imidazo[4,5-c]pyridin-7-ol, 2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl- chemical structure, C10H10N6O2, CAS 607373-65-9
1H-Imidazo[4,5-c]pyridin-7-ol, 2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-
CAS 607373-65-9C10H10N6O2
tert-Butyl 4-(7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylcarbamate chemical structure, C15H16BrClN6O3, CAS 842144-08-5
tert-Butyl 4-(7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylcarbamate
CAS 842144-08-5C15H16BrClN6O3
4-(6-Bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C10H8BrClN6O, CAS 913642-06-5
4-(6-Bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
CAS 913642-06-5C10H8BrClN6O
4-(4-Chloro-6-ethenyl-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C12H11ClN6O, CAS 913642-32-7
4-(4-Chloro-6-ethenyl-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
CAS 913642-32-7C12H11ClN6O
4-{3H-Imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-amine chemical structure, C8H6N6O, CAS 862815-00-7
4-{3H-Imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-amine
CAS 862815-00-7C8H6N6O
4-(7-Bromo-4-chloro-1-isopropyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C11H10BrClN6O, CAS 2375195-47-2
4-(7-Bromo-4-chloro-1-isopropyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
CAS 2375195-47-2C11H10BrClN6O
4-{7-Bromo-3H-imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-amine chemical structure, C8H5BrN6O, CAS 1996706-52-5
4-{7-Bromo-3H-imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-amine
CAS 1996706-52-5C8H5BrN6O
1,1-Dimethylethyl N-[4-[[2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]oxy]butyl]carbamate chemical structure, C19H26ClN7O4, CAS 1052112-30-7
1,1-Dimethylethyl N-[4-[[2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]oxy]butyl]carbamate
CAS 1052112-30-7C19H26ClN7O4
tert-Butyl N-(4-{7-bromo-3H-imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-yl)carbamate chemical structure, C13H13BrN6O3, CAS 2803826-96-0
tert-Butyl N-(4-{7-bromo-3H-imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-yl)carbamate
CAS 2803826-96-0C13H13BrN6O3
Akt kinase inhibitor hydrochloride chemical structure, C16H20ClN7O3, CAS 3026697-00-4
Akt kinase inhibitor hydrochloride
CAS 3026697-00-4C16H20ClN7O3