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Murcko scaffold

Ring system with 2 rings and 14 atoms

28 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 14
Chemicals: 28
With full pages: 8

Scaffold SMILES

O=S(=O)(c1ccccc1)c1cncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=S(=O)(c1ccccc1)c1cncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

p-Nitrophenyl-2-aminothiazol-5-ylsulphone chemical structure, C9H7N3O4S2, CAS 39565-05-4

p-Nitrophenyl-2-aminothiazol-5-ylsulphone

CAS 39565-05-4C₉H₇N₃O₄S₂

Thiazosulfone chemical structure, C9H9N3O2S2, CAS 473-30-3

CAS 473-30-3C₉H₉N₃O₂S₂

N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)pentanamide chemical structure, C14H15N3O5S2, CAS 361471-31-0

N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)pentanamide

CAS 361471-31-0C₁₄H₁₅N₃O₅S₂

2-Ethoxy-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}acetamide chemical structure, C13H13N3O6S2, CAS 600140-71-4

2-Ethoxy-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}acetamide

CAS 600140-71-4C₁₃H₁₃N₃O₆S₂

2-Chloro-N-[5-[(4-nitrophenyl)sulfonyl]-2-thiazolyl]acetamide chemical structure, C11H8ClN3O5S2, CAS 379255-52-4

2-Chloro-N-[5-[(4-nitrophenyl)sulfonyl]-2-thiazolyl]acetamide

CAS 379255-52-4C₁₁H₈ClN₃O₅S₂

N-[5-(4-Nitrophenyl)sulfonyl-1,3-thiazol-2-yl]methanesulfonamide chemical structure, C10H9N3O6S3, CAS 349626-01-3

N-[5-(4-Nitrophenyl)sulfonyl-1,3-thiazol-2-yl]methanesulfonamide

CAS 349626-01-3C₁₀H₉N₃O₆S₃

2-Allylthio-4-amino-5-tosylthiazole chemical structure, C13H14N2O2S3, CAS 117420-83-4

2-Allylthio-4-amino-5-tosylthiazole

CAS 117420-83-4C₁₃H₁₄N₂O₂S₃

4-Amino-5-(4-chlorophenylsulfonyl)-2-(propylthio)thiazole chemical structure, C12H13ClN2O2S3, CAS 494763-20-1

4-Amino-5-(4-chlorophenylsulfonyl)-2-(propylthio)thiazole

CAS 494763-20-1C₁₂H₁₃ClN₂O₂S₃

4-Amino-2-methylthio-5-tosylthiazole chemical structure, C11H12N2O2S3, CAS 117420-82-3

4-Amino-2-methylthio-5-tosylthiazole

CAS 117420-82-3C₁₁H₁₂N₂O₂S₃

4-Amino-2-methylthio-5-(phenylsulfonyl)thiazole chemical structure, C10H10N2O2S3, CAS 117420-80-1

4-Amino-2-methylthio-5-(phenylsulfonyl)thiazole

CAS 117420-80-1C₁₀H₁₀N₂O₂S₃

4-Amino-2-isopropylthio-5-(phenylsulfonyl)thiazole chemical structure, C12H14N2O2S3, CAS 117420-81-2

4-Amino-2-isopropylthio-5-(phenylsulfonyl)thiazole

CAS 117420-81-2C₁₂H₁₄N₂O₂S₃

4-Amino-2-isopropylthio-5-tosylthiazole chemical structure, C13H16N2O2S3, CAS 117420-84-5

4-Amino-2-isopropylthio-5-tosylthiazole

CAS 117420-84-5C₁₃H₁₆N₂O₂S₃

5-((4-Chlorophenyl)sulfonyl)-2-(methylthio)thiazol-4-amine chemical structure, C10H9ClN2O2S3, CAS 494763-21-2

5-((4-Chlorophenyl)sulfonyl)-2-(methylthio)thiazol-4-amine

CAS 494763-21-2C₁₀H₉ClN₂O₂S₃

2-Ethyl-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}hexanamide chemical structure, C17H21N3O5S2, CAS 349442-85-9

2-Ethyl-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}hexanamide

CAS 349442-85-9C₁₇H₂₁N₃O₅S₂

2-Methyl-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]butanamide chemical structure, C14H15N3O5S2, CAS 349541-10-2

2-Methyl-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]butanamide

CAS 349541-10-2C₁₄H₁₅N₃O₅S₂

2-Methyl-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}pentanamide chemical structure, C15H17N3O5S2, CAS 349541-97-5

2-Methyl-N-{5-[(4-nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}pentanamide

CAS 349541-97-5C₁₅H₁₇N₃O₅S₂

3-Ethoxy-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]propanamide chemical structure, C14H15N3O6S2, CAS 831205-55-1

3-Ethoxy-N-[5-(4-nitrophenyl)sulfonyl-1,3-thiazol-2-yl]propanamide

CAS 831205-55-1C₁₄H₁₅N₃O₆S₂

N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)isobutyramide chemical structure, C13H13N3O5S2, CAS 361471-27-4

N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)isobutyramide

CAS 361471-27-4C₁₃H₁₃N₃O₅S₂

N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)butyramide chemical structure, C13H13N3O5S2, CAS 476293-77-3

N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)butyramide

CAS 476293-77-3C₁₃H₁₃N₃O₅S₂

N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)propionamide chemical structure, C12H11N3O5S2, CAS 361471-22-9

N-(5-((4-Nitrophenyl)sulfonyl)thiazol-2-yl)propionamide

CAS 361471-22-9C₁₂H₁₁N₃O₅S₂

5-[(4-Methylphenyl)sulfonyl]-2-(propylthio)-4-thiazolamine chemical structure, C13H16N2O2S3, CAS 117420-85-6

5-[(4-Methylphenyl)sulfonyl]-2-(propylthio)-4-thiazolamine

CAS 117420-85-6C₁₃H₁₆N₂O₂S₃

3-(N-{5-[(4-Nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}carbamoyl)propanoic acid chemical structure, C13H11N3O7S2, CAS 857549-87-2

3-(N-{5-[(4-Nitrophenyl)sulfonyl]-1,3-thiazol-2-yl}carbamoyl)propanoic acid

CAS 857549-87-2C₁₃H₁₁N₃O₇S₂

5-Benzenesulfonylthiazole-4-carbaldehyde chemical structure, C10H7NO3S2, CAS 1161865-61-7

5-Benzenesulfonylthiazole-4-carbaldehyde

CAS 1161865-61-7C₁₀H₇NO₃S₂

N-[5-[(4-Aminophenyl)sulfonyl]-1,3-thiazol-2-yl]acetamide chemical structure, C11H11N3O3S2, CAS 99844-61-8

N-[5-[(4-Aminophenyl)sulfonyl]-1,3-thiazol-2-yl]acetamide

CAS 99844-61-8C₁₁H₁₁N₃O₃S₂