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Murcko scaffold

2-Cyclopropylpyrrolidine scaffold

209 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
209
With full pages
13
Scaffold SMILES

C1CNC(C2CC2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Cyclopropylpyrrolidine page
Murcko scaffold C1CNC(C2CC2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 209 chemicals

(2S,5S)-5-Cyclopropyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid chemical structure, C13H21NO4, CAS 2165873-98-1
(2S,5S)-5-Cyclopropyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
CAS 2165873-98-1C13H21NO4
(2R,5S)-1-tert-Butoxycarbonyl-5-cyclopropyl-pyrrolidine-2-carboxylic acid chemical structure, C13H21NO4, CAS 2640463-96-1
(2R,5S)-1-tert-Butoxycarbonyl-5-cyclopropyl-pyrrolidine-2-carboxylic acid
CAS 2640463-96-1C13H21NO4
(2S,5R)-1-tert-Butoxycarbonyl-5-cyclopropyl-pyrrolidine-2-carboxylic acid chemical structure, C13H21NO4, CAS 2165501-09-5
(2S,5R)-1-tert-Butoxycarbonyl-5-cyclopropyl-pyrrolidine-2-carboxylic acid
CAS 2165501-09-5C13H21NO4
(3R,5R)-5-Cyclopropylpyrrolidin-3-ol chemical structure, C7H13NO, CAS 2126144-73-6
(3R,5R)-5-Cyclopropylpyrrolidin-3-ol
CAS 2126144-73-6C7H13NO
2-(2,2-Difluoro-3-methylcyclopropyl)pyrrolidine hydrochloride chemical structure, C8H14ClF2N, CAS 2098018-74-5
2-(2,2-Difluoro-3-methylcyclopropyl)pyrrolidine hydrochloride
CAS 2098018-74-5C8H14ClF2N
2-[2,2-Difluoro-3-(propan-2-yl)cyclopropyl]pyrrolidine hydrochloride chemical structure, C10H18ClF2N, CAS 2098007-31-7
2-[2,2-Difluoro-3-(propan-2-yl)cyclopropyl]pyrrolidine hydrochloride
CAS 2098007-31-7C10H18ClF2N
2-(3-Ethyl-2,2-difluorocyclopropyl)pyrrolidine hydrochloride chemical structure, C9H16ClF2N, CAS 2098001-61-5
2-(3-Ethyl-2,2-difluorocyclopropyl)pyrrolidine hydrochloride
CAS 2098001-61-5C9H16ClF2N
2-[2,2-Difluoro-3-(methoxymethyl)cyclopropyl]pyrrolidine hydrochloride chemical structure, C9H16ClF2NO, CAS 2098020-48-3
2-[2,2-Difluoro-3-(methoxymethyl)cyclopropyl]pyrrolidine hydrochloride
CAS 2098020-48-3C9H16ClF2NO
Ethyl 2-[2,2-difluoro-3-(pyrrolidin-2-yl)cyclopropyl]acetate hydrochloride chemical structure, C11H18ClF2NO2, CAS 2098128-71-1
Ethyl 2-[2,2-difluoro-3-(pyrrolidin-2-yl)cyclopropyl]acetate hydrochloride
CAS 2098128-71-1C11H18ClF2NO2
2-(2,2-Difluorocyclopropyl)pyrrolidine hydrochloride chemical structure, C7H12ClF2N, CAS 2098003-26-8
2-(2,2-Difluorocyclopropyl)pyrrolidine hydrochloride
CAS 2098003-26-8C7H12ClF2N
2-(2,2-Difluorocyclopropyl)pyrrolidine chemical structure, C7H11F2N, CAS 2098003-25-7
2-(2,2-Difluorocyclopropyl)pyrrolidine
CAS 2098003-25-7C7H11F2N
tert-Butyl 2-cyclopropyl-4-hydroxypyrrolidine-1-carboxylate chemical structure, C12H21NO3, CAS 1824027-69-1
tert-Butyl 2-cyclopropyl-4-hydroxypyrrolidine-1-carboxylate
CAS 1824027-69-1C12H21NO3
tert-Butyl 2-(2-(mercaptomethyl)cyclopropyl)pyrrolidine-1-carboxylate chemical structure, C13H23NO2S, CAS 1823863-48-4
tert-Butyl 2-(2-(mercaptomethyl)cyclopropyl)pyrrolidine-1-carboxylate
CAS 1823863-48-4C13H23NO2S
tert-Butyl 2-[2-(aminomethyl)cyclopropyl]pyrrolidine-1-carboxylate chemical structure, C13H24N2O2, CAS 1823983-00-1
tert-Butyl 2-[2-(aminomethyl)cyclopropyl]pyrrolidine-1-carboxylate
CAS 1823983-00-1C13H24N2O2
2-(1-Acetylpyrrolidin-2-yl)cyclopropane-1-carboxylic acid chemical structure, C10H15NO3, CAS 1824277-90-8
2-(1-Acetylpyrrolidin-2-yl)cyclopropane-1-carboxylic acid
CAS 1824277-90-8C10H15NO3
1-(2-(2-(Hydroxymethyl)cyclopropyl)pyrrolidin-1-yl)ethanone chemical structure, C10H17NO2, CAS 1824264-44-9
1-(2-(2-(Hydroxymethyl)cyclopropyl)pyrrolidin-1-yl)ethanone
CAS 1824264-44-9C10H17NO2
1-(2-(2-(Bromomethyl)cyclopropyl)pyrrolidin-1-yl)ethanone chemical structure, C10H16BrNO, CAS 1824277-96-4
1-(2-(2-(Bromomethyl)cyclopropyl)pyrrolidin-1-yl)ethanone
CAS 1824277-96-4C10H16BrNO
1-(2-(2-(Methylamino)cyclopropyl)pyrrolidin-1-yl)ethanone chemical structure, C10H18N2O, CAS 1824264-73-4
1-(2-(2-(Methylamino)cyclopropyl)pyrrolidin-1-yl)ethanone
CAS 1824264-73-4C10H18N2O
(2-(1-Methylpyrrolidin-2-yl)cyclopropyl)methanol chemical structure, C9H17NO, CAS 1823250-90-3
(2-(1-Methylpyrrolidin-2-yl)cyclopropyl)methanol
CAS 1823250-90-3C9H17NO
2-(2-(Bromomethyl)cyclopropyl)-1-methylpyrrolidine chemical structure, C9H16BrN, CAS 1823250-95-8
2-(2-(Bromomethyl)cyclopropyl)-1-methylpyrrolidine
CAS 1823250-95-8C9H16BrN
2-(2-(Iodomethyl)cyclopropyl)-1-methylpyrrolidine chemical structure, C9H16IN, CAS 1824264-81-4
2-(2-(Iodomethyl)cyclopropyl)-1-methylpyrrolidine
CAS 1824264-81-4C9H16IN
(2-(1-Methylpyrrolidin-2-yl)cyclopropyl)methanethiol chemical structure, C9H17NS, CAS 1824054-06-9
(2-(1-Methylpyrrolidin-2-yl)cyclopropyl)methanethiol
CAS 1824054-06-9C9H17NS
N-Ethyl-2-(1-methylpyrrolidin-2-yl)cyclopropanamine chemical structure, C10H20N2, CAS 1824271-35-3
N-Ethyl-2-(1-methylpyrrolidin-2-yl)cyclopropanamine
CAS 1824271-35-3C10H20N2
N-Isopropyl-2-(1-methylpyrrolidin-2-yl)cyclopropanamine chemical structure, C11H22N2, CAS 1824054-15-0
N-Isopropyl-2-(1-methylpyrrolidin-2-yl)cyclopropanamine
CAS 1824054-15-0C11H22N2