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Murcko scaffold

Ring system with 3 rings and 17 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
14
With full pages
8
Scaffold SMILES

c1ccc(Cc2ccc3cccnc3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2ccc3cccnc3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

GNF-Pf-3257 chemical structure, C20H19ClN2O2, CAS 5923-95-5
GNF-Pf-3257
CAS 5923-95-5C20H19ClN2O2
N-[(4-Dimethylaminophenyl)-(8-hydroxyquinolin-7-yl)methyl]acetamide chemical structure, C20H21N3O2, CAS 5926-67-0
N-[(4-Dimethylaminophenyl)-(8-hydroxyquinolin-7-yl)methyl]acetamide
CAS 5926-67-0C20H21N3O2
N-[(8-Hydroxy-7-quinolinyl)(phenyl)methyl]propanamide chemical structure, C19H18N2O2, CAS 332173-48-5
N-[(8-Hydroxy-7-quinolinyl)(phenyl)methyl]propanamide
CAS 332173-48-5C19H18N2O2
Acetamide, N-[(5-chloro-8-hydroxy-7-quinolinyl)(2-methoxyphenyl)methyl]- chemical structure, C19H17ClN2O3, CAS 332939-49-8
Acetamide, N-[(5-chloro-8-hydroxy-7-quinolinyl)(2-methoxyphenyl)methyl]-
CAS 332939-49-8C19H17ClN2O3
N-[(2,4-Dichloro-phenyl)-(8-hydroxy-quinolin-7-yl)-methyl]-butyramide chemical structure, C20H18Cl2N2O2, CAS 332939-26-1
N-[(2,4-Dichloro-phenyl)-(8-hydroxy-quinolin-7-yl)-methyl]-butyramide
CAS 332939-26-1C20H18Cl2N2O2
N-((8-Hydroxyquinolin-7-yl)(4-isopropylphenyl)methyl)acetamide chemical structure, C21H22N2O2, CAS 332939-29-4
N-((8-Hydroxyquinolin-7-yl)(4-isopropylphenyl)methyl)acetamide
CAS 332939-29-4C21H22N2O2
N-((5-Chloro-8-hydroxyquinolin-7-yl)(phenyl)methyl)acetamide chemical structure, C18H15ClN2O2, CAS 332939-46-5
N-((5-Chloro-8-hydroxyquinolin-7-yl)(phenyl)methyl)acetamide
CAS 332939-46-5C18H15ClN2O2
N-[(8-Hydroxy-5-nitroquinolin-7-yl)-(2-methoxyphenyl)methyl]propanamide chemical structure, C20H19N3O5, CAS 333315-16-5
N-[(8-Hydroxy-5-nitroquinolin-7-yl)-(2-methoxyphenyl)methyl]propanamide
CAS 333315-16-5C20H19N3O5
N-[(5-Chloro-8-hydroxyquinolin-7-yl)[4-(diethylamino)phenyl]methyl]butanamide chemical structure, C24H28ClN3O2, CAS 333318-69-7
N-[(5-Chloro-8-hydroxyquinolin-7-yl)[4-(diethylamino)phenyl]methyl]butanamide
CAS 333318-69-7C24H28ClN3O2
N-[(8-Hydroxy-7-quinolinyl)(3-nitrophenyl)methyl]-2-methylpropanamide chemical structure, C20H19N3O4, CAS 332173-88-3
N-[(8-Hydroxy-7-quinolinyl)(3-nitrophenyl)methyl]-2-methylpropanamide
CAS 332173-88-3C20H19N3O4
N-[(5-Chloro-8-hydroxyquinolin-7-yl)[4-(dimethylamino)phenyl]methyl]-2-methylpropanamide chemical structure, C22H24ClN3O2, CAS 333445-77-5
N-[(5-Chloro-8-hydroxyquinolin-7-yl)[4-(dimethylamino)phenyl]methyl]-2-methylpropanamide
CAS 333445-77-5C22H24ClN3O2
N-((8-Hydroxyquinolin-7-yl)(phenyl)methyl)isobutyramide chemical structure, C20H20N2O2, CAS 5925-62-2
N-((8-Hydroxyquinolin-7-yl)(phenyl)methyl)isobutyramide
CAS 5925-62-2C20H20N2O2
Ethyl ((5-chloro-8-hydroxyquinolin-7-yl)(4-(dimethylamino)phenyl)methyl)carbamate chemical structure, C21H22ClN3O3, CAS 2817309-82-1
Ethyl ((5-chloro-8-hydroxyquinolin-7-yl)(4-(dimethylamino)phenyl)methyl)carbamate
CAS 2817309-82-1C21H22ClN3O3
1-(8-(Methoxymethoxy)quinolin-7-yl)-N-methyl-1-phenylmethanamine chemical structure, C19H20N2O2, CAS 2449224-48-8
1-(8-(Methoxymethoxy)quinolin-7-yl)-N-methyl-1-phenylmethanamine
CAS 2449224-48-8C19H20N2O2